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Bovine genome provides clues to possible new developments
Date:4/23/2009

ew avenues in cattle research that were not available to us previously," Womack says. "It's a huge step in the field of cattle research."

His colleague in much of the work was Dr. Loren Skow, also a faculty member in the CVM.

Gill hosted the DNA repository from cattle around the world. Gill is using the SNP resources generated in this study to tie information into the agency's own cattle mapping resource at the AgriLife Research Center in McGregor.

Gill also led a team that annotated the genes detailed in "Science" and received contributions from students in her applied animal genomics graduate-level course. Contributing to the research were graduate students Carl Muntean, Cody Gladney, Natasha Romero and Jungwoo Choi. Undergraduates Clayton Boldt and Jennifer Chapin contributed annotations, as well as Kris Wunderlich (doctoral candidate) and Colette Abbey (research associate). AgriLife Research scientists Drs. Penny Riggs and Tom Welsh also contributed to the annotation process.

Womack said the cattle sequence took six years to complete, annotate and analyze with more than 300 scientists from 25 countries. Most of more than 25 companion reports describing detailed analyses of the two projects by the Bovine Sequencing Project and the Bovine Hapmap Consortia appear online at www.biomedcentral.com in a special electronic issue of the BioMed Central journal group.

"The future challenge will be to explore the bovine genome sequence in greater depth to fully understand the genetic basis of the evolutionary success of ruminants as this will provide opportunities to address some of the crucial issues of the present time efficient and sustainable food production for a rapidly increasing human population," said Dr. Richard Gibbs, director of the BCM Human Genome Sequencing Center and principal investigator on the project.

The authors concluded that the bovine genome, consisting of at least 22,000 genes, is more similar to that of human
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Contact: Blair Fannin
b-fannin@tamu.edu
979-845-2259
Texas A&M University
Source:Eurekalert

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