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Boston College names Thomas Chiles the Deluca Professor of Biology
Date:2/28/2012

CHESTNUT HILL, MA -- Boston College Biology Department Chairman Thomas Chiles has been named the Dr. Michael E. and Dr. Salvatore A. DeLuca Professor of Biology, the university announced today.

Chiles, whose research into lymphocyte metabolism and cancer biology is funded by the National Cancer Institute, the National Institutes of Health and private foundations, said he was honored to receive the endowed professorship, which will support his ongoing research, particularly projects involving undergraduates.

"It is a privilege and an honor to be named the DeLuca Professor of Biology," said Chiles, who joined the BC faculty in 1992. "I'm grateful to the University and the DeLuca family for their ongoing support of my lab's work and the advancement of the biological sciences here at BC."

Chiles' research focuses on understanding how a subset of lymphocytes, also known as B cells, grow and survive. The white blood cells play a critical role in the infectious disease-fighting ability of the immune system. Chiles' research has focused on how B cells respond to their environment in order to produce antibodies and regulatory cytokines and are able to adapt to survive while fighting pathogens and infectious agents.

That research led Chiles into an area known as metabolomics to study how the B cell's metabolism changes in response to external cues such as pathogens in order to support its radical transformation to an antibody producing plasma cell. In collaboration with Chemistry Professor Mary Roberts, the research is also providing insight into how energy metabolism is altered in cancer cells to support their growth and survival.

Chiles is also part of a multi-disciplinary team of campus scientists developing the next generation of nanosensors capable of detecting minute amounts of cancer biomarkers that signal the presence of disease. Developed in collaboration with Biology Research Professor Dong Cai and Physics Profes
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Contact: Ed Hayward
ed.hayward@bc.edu
617-552-4826
Boston College
Source:Eurekalert  

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