Navigation Links
Bone grafting improvements with the help of sea coral
Date:11/28/2013

t can cause discomfort, pain and long-term impairment in the area that the bone is taken from.

In their study, the researchers, from the UK and China, harvested sea coral from South China and partially converted the calcium carbonate into CHA to form CHACC.

According to the paper, the CHACC composition, which contains 15 per cent of CHA in a thin layer around the calcium carbonate, has the strong, porous structure that has made CHA commercially successful, but contains significantly improved biodegrading properties to support natural bone healing.

In their study, the researchers constructed CHACC and tested its physical and chemical properties using a number of microscopic and spectroscopic techniques. The CHACC was then mixed with human mesenchymal stem cells and implanted subcutaneously in mice for 10 weeks. The results showed that new bone formation was visible on the surface of the CHACC.

In a preliminary clinical study, 16 patients (11 male and five female) with a range of four different bone defects were surgically implanted with CHACC. Results showed there was clinical bone healing four months after surgery and the majority of the implanted CHACC degraded after 18 to 24 months in each patient.

Bone remodelling can be a complex and slow process by which old bone is continuously replaced by new bone tissue. In the case of fracture healing, the complete remodelling phase can take between three and five years depending on the individual, so a synthetic bone graft must biodegrade within a time window that relates to the natural bone remodelling cycle.

The researchers acknowledge that there is some way to go until the material can match the benefits of an autograft and be used on the several million people worldwide who undergo bone grafting procedures each year.

"Although our study has provided promising results, the CHACC material does not contain a bone organic matrix, living cells and the ability to
'/>"/>

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UTSA, Southwest Research Institute to develop drug-loaded scaffold for bone grafting
2. Lake Mead aquatic-science research documents substantial improvements in ecosystem
3. Unraveling the threads: Simplest cotton genome offers clues for fiber improvements
4. New Study Shows That Improvements in Employee Health Behaviors Persist Over Two Years
5. Blue Ribbon Panel unveils findings on logistical improvements to support Antarctic science
6. Research on improvements in diagnosing and treating tuberculosis
7. EWiND facility aimed at improvements in wind energy
8. Large study shows pollution impact on coral reefs -- and offers solution
9. Safety in numbers? Not so for corals
10. The Gorgons of the eastern Pacific: scientists describe 2 new gorgonian soft coral species
11. New study suggests coral reefs may be able to adapt to moderate climate change
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... Research and Markets  has announced the addition of ... to their offering. Biometrics is a ... of their physical or behavioral patterns. It involves the ... fingerprints, face recognition, DNA, palm print, hand geometry, and ... and speech pattern/voice recognition. The data ...
(Date:10/22/2014)... -- Leading identity analyst firm Acuity Market Intelligence forecasts that ... will have a chip-based National eID card, including near-complete ... Asia , with its vast population, is ... 60% of all National eID cards issued between 2014 ... National eID Industry Report: 2014 Edition" — ...
(Date:10/18/2014)... 19th October 2014 Psychological stress and stress-related psychiatric ... aging-related diseases, but the molecular mechanisms underlying ... may contribute to the development of targeted ... for these devastating diseases. This work is ... congress in Berlin., Now an international group ...
Breaking Biology News(10 mins):Biometrics Market in Europe 2014-2018: Key Vendors are 3M Cogent, Cognitec, NEC and Safran 2Biometrics Market in Europe 2014-2018: Key Vendors are 3M Cogent, Cognitec, NEC and Safran 3Half the World's Population Will Have Chip-Based National Electronic Identity (eID) Cards by 2018 2Researchers find why depression and aging linked to increased disease risk 2
... the atmosphere and moving into marine systems, the world,s ... To address the growing concern for acidifying marine systems, ... under the Ocean Acidification theme of its Climate Research ... Office of Polar Programs, Directorate for Geosciences, and Directorate ...
... October 13, 2010) Before Alzheimer,s patients experience memory loss, ... A new study in mouse models by researchers ... mitochondria -- the powerhouses of the cell -- are one ... appeared in the online Early Edition of PNAS, also found ...
... North American comb jellyfish can sneak up on its ... successful predator. Researchers, including one from the University of ... jellyfish makes itself hydrodynamically ,invisible,. The North American ... known to consume vast quantities of zooplankton. A few ...
Cached Biology News:NSF awards grants to study effects of ocean acidification 2NSF awards grants to study effects of ocean acidification 3NSF awards grants to study effects of ocean acidification 4NSF awards grants to study effects of ocean acidification 5NSF awards grants to study effects of ocean acidification 6NSF awards grants to study effects of ocean acidification 7NSF awards grants to study effects of ocean acidification 8NSF awards grants to study effects of ocean acidification 9NSF awards grants to study effects of ocean acidification 10Early role of mitochondria in AD may help explain limitations to current beta amyloid hypothesis 2Voracious comb jellyfish 'invisible' to prey 2
(Date:10/22/2014)... YORK , Oct. 22, 2014 New ... in the in vitro diagnostic (IVD) test industry, especially ... Information. The healthcare market researcher listed more than 25 testing ... could be the future of IVD products. Kalorama details the ... The Worldwide Market for In Vitro Diagnostic Tests ...
(Date:10/22/2014)... The North American crystal oscillator market report defines ... and forecast of revenue. This market was valued at ... $623.6 million by 2018, at a CAGR of 3.3% ... of the North American crystal oscillator market report, to ... also provides a glimpse of the segmentation of the ...
(Date:10/22/2014)... San Diego, CA (PRWEB) October 22, 2014 ... laboratory balances from Sartorius, A & D Weighing, ... Sartorius CPA Semi-Micro Balance . The Sartorius ... looking for an affordable high-quality, precise, and user-friendly ... in manufacturing of laboratory equipment, their laboratory balances ...
(Date:10/22/2014)...   Synthetic Biologics, Inc. (NYSE MKT: SYN), ... infections and diseases, announced today that the U.S. Patent ... for a composition of matter patent application that covers ... SYN-004. This is Synthetic Biologics, first allowed patent application ... to the Company,s extensive C. difficile patent ...
Breaking Biology Technology:Report: Radical New IVD Test Approaches Key To Growth 2Report: Radical New IVD Test Approaches Key To Growth 3The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 2The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 3The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 4Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 2Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 2Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 4
... Sangamo BioSciences, Inc. (Nasdaq: SGMO ) today ... and year-end 2008 financial results on Wednesday, February 4, ... be followed by a conference call at 5:00 p.m. ... telephone and webcast. During the conference call, the company ...
... a,subsidiary of KV Pharmaceutical (NYSE: KVa/KVb), is issuing, ... 26, 2009, a nationwide,voluntary recall of the products ... a wholesale or a retail level as a ... conditions that did not,sufficiently comply with current Good ...
... Japan,s first second-generation drug-eluting stentNATICK, Mass., Jan. 28 ... ) announced today that it has received approval ... Welfare (MHLW) to market its TAXUS(R) Liberte(R) Paclitaxel-Eluting ... launch the product as soon as reimbursement approval ...
Cached Biology Technology:Sangamo BioSciences Announces Fourth Quarter and Year-End 2008 Conference Call and Webcast 2Sangamo BioSciences Announces Fourth Quarter and Year-End 2008 Conference Call and Webcast 3ETHEX Corporation Issues Nationwide Voluntary Recall of Products 2ETHEX Corporation Issues Nationwide Voluntary Recall of Products 3ETHEX Corporation Issues Nationwide Voluntary Recall of Products 4ETHEX Corporation Issues Nationwide Voluntary Recall of Products 5ETHEX Corporation Issues Nationwide Voluntary Recall of Products 6Boston Scientific Announces Japanese Approval for TAXUS(R) Liberte(R) Drug-Eluting Stent System 2Boston Scientific Announces Japanese Approval for TAXUS(R) Liberte(R) Drug-Eluting Stent System 3