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Body rebuilding: Researchers regenerate muscle in mice
Date:11/29/2011

muscle fibers, may encourage resident mouse progenitor cells to migrate into the wound and begin restoring the tissue (they may also forestall the natural inflammatory response that leads to scarring after a major injury).

This surprise finding suggests that fibrin microthreads alone could be used to treat major muscle trauma while research on enhancing regeneration with reprogrammed human cells continues. "The contribution of the fibrin microthreads alone to wound healing should not be understated," the authors wrote. "While this clearly points to room for improving cell delivery techniques, it suggests that fibrin microthreads alone have tremendous potential for reducing fibrosis and remodeling large muscle injuries. Future studies will address, more completely, the capability of microthreads alone and determine, at what point, a combinational cell therapy is required for full functional tissue restoration."


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Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute
Source:Eurekalert  

Page: 1 2 3

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