Navigation Links
Blueberry's effects on cholesterol examined in lab animal study
Date:5/31/2011

This release is available in Spanish.

Laboratory hamsters that were fed rations spiked with blueberry peels and other blueberry-juice-processing leftovers had better cholesterol health than hamsters whose rations weren't enhanced with blueberries. That's according to a study led by U.S. Department of Agriculture (USDA) chemist Wallace H. Yokoyama.

Yokoyama pointed out that further research is needed to confirm whether the effects observed in hamsters hold true for humans. He works at the Western Regional Research Center operated in Albany Calif., by the Agricultural Research Service (ARS), the principal scientific research agency of USDA.

In the investigation, hamsters were fed high-fat rations. For some animals, those rations were supplemented with one of three different kinds of juice byproducts: blueberry skins-that is, peels leftover when berries are pressed to make juice; fiber extracted from the peels; or natural compounds known as polyphenols, also extracted from the peels. Blueberry polyphenols give the fruit its purple, blue, and red coloration.

In an article published in the Journal of Agricultural and Food Chemistry in 2010, Yokoyama and his coinvestigators reported that all the hamsters that were fed blueberry-enhanced rations had from 22 to 27 percent lower total plasma cholesterol than hamsters fed rations that didn't contain blueberry juice byproducts.

Levels of VLDL (very low density lipoprotein-a form of "bad" cholesterol) were about 44 percent lower in the blueberry-fed hamsters.

Yokoyama and his coinvestigators used a procedure known as real-time reverse transcription polymerase chain reaction, or RT-PCR, to learn about the genes responsible for these effects. This approach allowed the scientists to pinpoint differences in the level of activity of certain liver genes.

In hamsters-and in humans-the liver both makes cholesterol and helps get rid of excessive levels of it. Results suggest that activity of some liver genes that either produce or use cholesterol resulted in the lower blood cholesterol levels.

The study is apparently the first published account of cholesterol-lowering effects in laboratory hamsters fed blueberry peels or fiber or polyphenols extracted from those peels.

Of course, some pieces of the cholesterol puzzle are not yet in place. For example, the researchers don't know which berry compound or compounds activated the liver genes, or which parts of the berry have the highest levels of these compounds.


'/>"/>

Contact: Marcia Wood
marcia.wood@ars.usda.gov
301-504-1662
United States Department of Agriculture - Research, Education and Economics
Source:Eurekalert

Related biology news :

1. Effects of celiac disease on bone mineral density are pronounced in lumbar spine than femoral neck
2. Heredity behind subjective effects of alcohol
3. Studies focus on feed ingredients effects on levels of E. coli O157:H7 in cattle
4. A new research report shows effects of climate change in the Arctic are more extensive than expected
5. Webcam technology used to measure medications effects on the heart
6. Lollipops with side effects
7. Louisiana, Florida residents differ on views of long-term effects of oil spill
8. Nanopolymer shows promise for helping reduce cancer side effects
9. Epidemiological study demonstrates climate change effects on forests
10. New study shows you can have your candy and eat it too -- without adverse health effects
11. Good cholesterol structure identified, could help explain protective effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2017)... The biometrics market has reached a ... organizations, desires to better authenticate or identify users ... challenge questions), biometrics is quickly working its way ... is driven by use cases, though there traditionally ... uses cases, with consumer-facing use cases encompassing authentication, ...
(Date:2/6/2017)... Feb. 6, 2017 According to Acuity ... driving border authorities to continue to embrace biometric ... are 2143 Automated Border Control (ABC) eGates and ... at more than 163 ports of entry across ... 2016 achieving a combined CAGR of 37%. APC ...
(Date:2/2/2017)... 2017  Central to its deep commitment to ... The Japan Prize Foundation today announced the laureates ... the envelope in their respective fields of Life ... are being recognized with the 2017 Japan Prize ... contribute to the advancement of science and technology, ...
Breaking Biology News(10 mins):
(Date:2/22/2017)... Linda, Ca (PRWEB) , ... February 22, 2017 , ... ... innovators, engineers, and scientists from around the world, is pleased to announce the launch ... science, technology, engineering and mathematics (STEM) fields. , This merit-based scholarship is open to ...
(Date:2/22/2017)... DIEGO , Feb. 22, 2017 Aethlon ... the results of a study that validated the ability ... that are associated with increased mortality in immune-suppressed sepsis ... patients. The objective of the study ... of Cytomegalovirus (CMV), Epstein-Barr virus (EBV) and Herpes Simplex ...
(Date:2/22/2017)... and SAN DIEGO , Feb. ... "Company") (OTCQB:CELZ) announced today expansion of its translational ... cell product through establishment of laboratory facilities in ... at the San Diego BioLabs facility, a biotechnology ... Novartis, and Sanofi. In November 2016, ...
(Date:2/21/2017)... 2017 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or the "Company") (TSX-V: ... the three months ended December 31, 2016. ... and diagnostics company that develops and commercializes proprietary technologies and ... ... the commercial milestones achieved in fiscal 2016," said Andrew ...
Breaking Biology Technology: