Navigation Links
Blueberries help fight artery hardening, lab animal study indicates

This release is available in Spanish.

Blueberries may help fight atherosclerosis, also known as hardening of the arteries, according to results of a preliminary U.S. Department of Agriculture (USDA)-funded study with laboratory mice. The research provides the first direct evidence that blueberries can help prevent harmful plaques or lesions, symptomatic of atherosclerosis, from increasing in size in arteries.

Principal investigator Xianli Wu, based in Little Rock, Ark., with the USDA Agricultural Research Service (ARS) Arkansas Children's Nutrition Center and with the University of Arkansas for Medical Sciences, led the investigation. The findings are reported in the current issue of the Journal of Nutrition.

Atherosclerosis is the leading cause of two forms of cardiovascular disease--heart attacks and strokes. Cardiovascular disease is the number one killer of Americans.

The study compared the size, or area, of atherosclerotic lesions in 30 young laboratory mice. Half of the animals were fed diets spiked with freeze-dried blueberry powder for 20 weeks; the diet of the other mice did not contain the berry powder.

Lesion size, measured at two sites on aorta (arteries leading from the heart), was 39 and 58 percent less than that of lesions in mice whose diet did not contain blueberry powder.

Earlier studies, conducted elsewhere, have suggested that eating blueberries may help combat cardiovascular disease. But direct evidence of that effect has never been presented previously, according to Wu.

The blueberry-spiked diet contained 1 percent blueberry powder, the equivalent of about a half-cup of fresh blueberries.

All mice in the investigation were deficient in apolipoprotein-E, a trait which makes them highly susceptible to forming atherosclerotic lesions and thus an excellent model for biomedical and nutrition research.

Wu's group wants to determine the mechanism or mechanisms by which blueberries helped control lesion size. For example, by boosting the activity of four antioxidant enzymes, blueberries may have reduced the oxidative stress that is a known risk factor for atherosclerosis.

In followup studies, Wu's group wants to determine whether eating blueberries in infancy, childhood and young adulthood would help protect against onset and progression of atherosclerosis in later years. Early prevention may be especially important in light of the nation's epidemic of childhood obesity. Overweight and obesity increase atherosclerosis risk.


Contact: Marcia Wood
United States Department of Agriculture -- Research, Education and Economics

Related biology news :

1. Plums poised to give blueberries run for the money
2. Proteins to yield new clues in fight against osteoporosis
3. New infrared light may open new frontier in fighting cancer, Tay Sachs
4. U of Alberta researchers discover important mechanism in fighting infection
5. U of M researchers identify 2 FDA approved drugs that may fight HIV
6. How corals fight back
7. Coastal creatures may have reduced ability to fight off infections in acidified oceans
8. Middle school students co-author research on enzyme for activating promising disease-fighters
9. Biology, computer science combine efforts to fight cancer
10. Dairy farmers can fight growing disease threat with chlorine and stainless steel
11. WPI research shows how cranberry juice fights bacteria at the molecular level
Post Your Comments:
(Date:11/17/2015)... , November 17, 2015 ... 19 novembre  2015.  --> Paris , ... --> DERMALOG, le leader de l,innovation biométrique, a ... fois passeports et empreintes sur la même surface de ... passeports et l,autre pour les empreintes digitales. Désormais, un ...
(Date:11/17/2015)... 17, 2015 Pressure BioSciences, Inc. (OTCQB: PBIO) ... and sale of broadly enabling, pressure cycling technology ("PCT")-based ... today announced it has received gross proceeds of $745,000 ... Placement (the "Offering"), increasing the total amount raised to ... additional closings are expected in the near future. ...
(Date:11/12/2015)... 2015  A golden retriever that stayed healthy despite ... has provided a new lead for treating this muscle-wasting ... Institute of MIT and Harvard and the University of ... Cell, pinpoints a protective gene that ... effects. The Boston Children,s lab of Lou Kunkel ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... November 25, 2015 2 nouvelles études ... les différences entre les souches bactériennes retrouvées dans ... des êtres humains . Ces recherches  ouvrent une ... la prise en charge efficace de l,un des ... les chats .    --> 2 nouvelles ...
(Date:11/25/2015)... ... 2015 , ... A long-standing partnership between the Academy of ... formalized with the signing of a Memorandum of Understanding. , AMA Executive Director ... Minter and Capt. Albert Glenn Tuesday, November 24, 2015, at AMA Headquarters in ...
(Date:11/24/2015)... ... November 24, 2015 , ... The United States Golf Association (USGA) ... USGA Green Section Award. Presented annually since 1961, the USGA Green Section Award recognizes ... with turfgrass. , Clarke, of Iselin, N.J., is an extension specialist of ...
(Date:11/24/2015)... ... 24, 2015 , ... International Society for Pharmaceutical Engineering (ISPE) ... annual events for pharmaceutical manufacturing: 2015 Annual Meeting. The conference took place in ... largest number of attendees in more than a decade. , “The 2015 ...
Breaking Biology Technology: