Navigation Links
Blue light culprit in red tide blooms
Date:2/23/2012

San Diego, Calif. Each year, phytoplankton blooms known as "red tides" kill millions of fish and other marine organisms and blanket vast areas of coastal water around the world. Though the precise causes of red tides remain a mystery, a team of researchers in the United States and Spain has solved one of the main riddles about these ecological disasters by uncovering the specific mechanism that triggers phytoplankton to release their powerful toxins into the environment.

"Previous theories about how phytoplankton release toxins proposed a rather awkward, untested 'exudation' mechanism," said researcher Pedro Verdugo of the University of Washington in Friday Harbor. "The true mechanism has been a very exciting riddle to crack and it provides a handle on understanding the development of huge phytoplankton blooms, eventually affecting several square miles of the ocean's upper surface."

Verdugo and his colleagues, Kellie L. Vigna also of the University of Washington and Ivan Quesada of the Universidad Miguel Hernandez in Alicante, Spain, will present their research at the 56th Annual Meeting of the Biophysical Society (BPS), held Feb. 25-29 in San Diego, Calif.

Red tides appear when naturally occurring algae including Karenia brevis multiply very rapidly, becoming so concentrated that the ocean surface takes on a reddish hue. Karenia produces brevetoxin, a powerful neurotoxin that binds to nerve and muscle cells, leading to substantial marine life mortality and human morbidity. The blooms are triggered by some as yet unknown fluctuations in ocean temperature, salinity, and available nutrients.

The researchers discovered that Karenia and other unicellular microalgae function very much like the secretory cells we have in our bodies. Namely, they store inside membrane-lined microscopic vesicles their active chemicals such as hormones, antibacterial products, and, in Karenia's case, toxins. When properly stimulated, these cells release their cargo by a process known as exocytosis.

Secretory cells store high concentrations of active chemicals in their vesicles by "caging" them in a gel matrix, as Verdugo's lab discovered more than a decade ago. This trick offers a clever thermodynamic advantage as storage across membrane-lined vesicles would otherwise require large amounts of osmotic work. According to the researchers, these microscopic gels found inside virtually all secretory vesicles remain in a condensed gel phase with their cargo virtually immobilized until they are released from the cell, when they undergo drastic swelling and release their payload. "Swelling results from a polymer gel phase transition, a characteristic property of both natural and synthetic polymer gels, which has been further applied in our lab to engineer high payload drug delivery vesicles," said Verdugo.

The cargo in phytoplankton vesicles are toxins. They are caged in a gel matrix made up of a biopolymer very similar to alginate, one of the constituents of algae cell walls. The researchers discovered that phytoplankton release their toxin-loaded gels when exposed to sunlight, particularly the blue portion of the spectrum.

"We do not know why phytoplankton respond to blue light, but it might be associated with the fact that blue light penetrates deeper in seawater," said Verdugo. "Often, plants and animals release toxins as a defense mechanism. Whether this is the case in phytoplankton remains speculative. However, blue light stimulation implies that these cells must have a photoreceptor most likely associated with the cell structures known as chloroplasts, which are responsible for photosynthesis. This is in fact one of the riddles we'll tackle next."

These observations support the notion that Karenia brevis functions as a typical secretory cell, which the researchers believe opens the way to a better understanding of red tide bloom dynamics.

The presentation, "Exocytic mechanisms of storage and release of brevotoxin in the dinoflagellate Karenia brevis," is at 1:45 p.m. on Monday, Feb. 27, 2012, in the San Diego Convention Center, Hall FGH. ABSTRACT: http://tinyurl.com/6nuttzl


'/>"/>

Contact: Ellen R. Weiss
eweiss@biophysics.org
240-290-5606
American Institute of Physics
Source:Eurekalert

Related biology news :

1. VIB-BGI Genomics Meeting highlights growing impact of large-scale genomics in life sciences
2. New study sheds light on genetics of rice metabolism
3. Highlights of the Biophysical Society 56th Annual Meeting
4. Study shines light on ways to cut costs for greenhouse growers
5. New study sheds light on evolutionary origin of oxygen-based cellular respiration
6. Research highlights key role grandmothers play in mother and child nutrition and health
7. Anti-malaria drug synthesized with the help of oxygen and light
8. Powering electric vehicles with sunlight
9. AGU journal highlights -- Jan. 13, 2012
10. Light makes write for DNA information-storage device
11. Sunlight and bunker oil a fatal combination for Pacific herring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... LIVERMORE, Calif. , March 21, 2017 ... recognition analytics company serving law enforcement agencies, announced today ... Sheridan as director of public safety business development. ... of diversified law enforcement experience, including a focus on ... Vigilant. In his most recent position, Mr. Sheridan served ...
(Date:3/9/2017)... Australia , March 9, 2017 4Dx ... prestigious World Lung Imaging Workshop at the University of ... was invited to deliver the latest data to world ... recognised event brings together leaders at the forefront of ... in lung imaging. "The quality of ...
(Date:3/2/2017)... 2, 2017 Summary This report provides ... its partnering interests and activities since 2010. ... Read the full report: ... since 2010 report provides an in-depth insight into the partnering ... On demand company reports are prepared upon purchase ...
Breaking Biology News(10 mins):
(Date:3/22/2017)... Denmark , March 22, 2017  Ascendis ... utilizes its innovative TransCon technology to address significant ... financial results for the full year ended December ... significant year for our company as we broadened ... a leading, integrated rare disease company with an ...
(Date:3/22/2017)... , March 22, 2017 The ... states a research report by Transparency Market Research (TMR). ... Amgen Inc., and AbbVie Inc., accounted for a share ... prominent players in this market are focusing aggressively on ... portfolio, which is likely to lead to market consolidation ...
(Date:3/22/2017)... ... March 21, 2017 , ... Premier executive recruitment firm, Slone ... Search Firm by Hunt Scanlon Media. , Hunt Scanlon Media is one ... widely referenced global news source in the human capital sector. , “It is a ...
(Date:3/22/2017)... ... 21, 2017 , ... The Conference Forum has announced the launch of the ... May 10-11, 2017, at the Colonnade Hotel in Boston, MA. The CMO Summit is ... learning, benchmarking and support. , “The Chief Medical Officer faces a unique set of ...
Breaking Biology Technology: