Navigation Links
Blood vessel forming potential of stem cells from human placenta and umbilical cord blood
Date:7/19/2012

Tampa, Fla. (July 19, 2012) A study comparing whether endothelial colony-forming cells (ECFCs) derived from human placenta or those derived from human umbilical cord blood are more proliferative and better for forming new blood vessels has found that ECFCs derived from human placenta are more vasculogenic.

The study, carried out by researchers at the Indiana School of Medicine, is published in a recent issue of Cell Medicine [2(3)] and is freely available on-line at: http://www.ingentaconnect.com/content/cog/cm.

"Circulating ECFCs isolated from umbilical cord blood and those isolated from human placenta are phenotypically identical and have equivalent proliferative potential," said study lead author Michael P. Murphy, MD of the Indiana University's Department of Surgery. "After transplantation, the circulating placenta-derived ECFCs formed significantly more blood vessels in vivo than the ECFCs derived from umbilical cord blood, indicating not only that there are inherent functional differences between resident and circulating ECFC populations, but that the placenta-derived cells are more vasculogenic."

Umbilical cord blood and the extra-embryonic membranes of placenta are ideal sources of progenitor cells, said the researchers, because the tissues are discarded as medical waste and ethical concerns facing embryonic stem cells are avoided. The quantity of cells that can be derived from placenta, however, is much greater than the amount that can be derived from umbilical cord blood, making the placenta the more abundant source.

They concluded that the placenta represents an abundant source of ECFCs that could provide a therapeutic dose of cells.

"The potential volume of placenta-derived ECFCs that can be harvested from a single placenta would provide a sufficient dose of cells without the necessity of expansion," noted Murphy.

According to the researchers, the role
'/>"/>

Contact: David Eve
cellmedicinect@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. True blood: SLU scientist investigates clotting factors
2. Dinosaurs were warm-blooded reptiles
3. Blood-brain barrier building blocks forged from human stem cells
4. Boosting blood system protein complex protects against radiation toxicity
5. New study: Snacking on raisins significantly reduces overall post-meal blood sugar levels
6. Manipulating chromatin loops to regulate genes may offer future treatments for blood diseases
7. Common genetic mutation increases sodium retention, blood pressure
8. John Theurer Cancer Center presents significant blood cancer research at 2012 ASCO Annual Meeting
9. New microscope uses rainbow of light to image the flow of individual blood cells
10. VolitionRX Raises Over $1 Million To Begin Clinical Trials of Blood Based Diagnostic Tests
11. Leeches are DNA bloodhounds in the jungle
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... Why do male ... reproduce? And why are there two sexes anyway? These and ... the research journal Molecular Human Reproduction published today ... University Bielefeld has compiled this special issue on sperm competition. ... copulate with several males in quick succession – chimpanzees are ...
(Date:10/17/2014)... . To date, ... overdoses, doctors are often limited to supportive therapy such as ... combination of drugs involved. So what can be done if ... ETH professor Jean-Christophe Leroux from the Institute of Pharmaceutical Sciences ... question. "The task was to develop an agent that could ...
(Date:10/16/2014)... William and Mary,s Virginia Institute of Marine Science ... Environmental Protection Agency to identify the streams and ... develop tools to help local governments and citizens ... critically on a dataset of tidal-marsh observations first ... with this historical baseline can today,s researchers accurately ...
Breaking Biology News(10 mins):Sperm wars 2Emergency aid for overdoses 2Emergency aid for overdoses 3EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3
... bacterial community living under extreme conditions almost two miles ... mine. It is the first microbial community demonstrated to ... and one of the few ecosystems found on Earth ... in any way. The discovery, appearing in the October ...
... An examination of 4 cases of botulism following cosmetic ... a highly concentrated, unlicensed preparation that resulted in toxin ... dose, according to a report in the November 22/29 ... paralytic illness caused by the toxins of the spore-forming ...
... further than the air around you. It could be ... to a first-of-its-kind census of airborne microbes recently conducted ... Berkeley National Laboratory (Berkeley Lab). , The team ... in air samples taken from the Texas cities of ...
Cached Biology News:Otherworldly bacteria discovered two miles down 2Highly concentrated botulinum preparation for cosmetic injections can result in severe illness 2Highly concentrated botulinum preparation for cosmetic injections can result in severe illness 3Study finds the air rich with bacteria 2Study finds the air rich with bacteria 3Study finds the air rich with bacteria 4
(Date:10/22/2014)... NJ (PRWEB) October 22, 2014 ... and services – has been working with a team ... and New Haven Farms Community Farming Collaborative to provide ... ePRO solution. The study, which started in May, ... program that provides participants weekly exposure to and participation ...
(Date:10/22/2014)... ROCKVILLE, Md. , Oct. 22, 2014   ... company developing novel pathogen-specific therapies for serious infections and ... Office has issued a Notice of Allowance for a ... product in its C. difficile program, SYN-004. This ... to SYN-004 in the U.S. and adds to the ...
(Date:10/20/2014)... The report “Pharmacy Automation Systems ... and Labeling Systems, Table-top Counters) by End-user (Inpatient ... & Trends to 2019” analyzes and studies the ... America, Europe, Asia-Pacific, and the Rest of the ... 30 figures spread through 300 pages and in-depth ...
(Date:10/20/2014)... -- , A major pan-European survey into ... of care has revealed changing trends in many important ... provision of healthcare services across the continent. The results ... Gastroenterology (UEG), have been announced today and led to ... burden of GI disorders across Europe ...
Breaking Biology Technology:myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 2myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 2Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 4Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 2Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5
... , , , VILNIUS, Lithuania, ... a provider of high-precision biometric identification technologies, has released new versions of the ... identification. The latest SDK versions, VeriFi n ger 6.1 ... VeriE y e 2.1 and MegaM ...
... Aug. 24 In response to the quickly emerging need ... for their members or constituents, tech startup Engageon LLC officially ... The first launch was developed for the National Lipid Association ... . lipid.org . Typically, most organizations have a ...
... NORWOOD, Mass., Aug. 24 Advanced Instruments has introduced ... business experience when purchasing osmometers, cryoscopes, and microbiological laboratory instruments. ... i es.com , was developed from the perspective ... and application information, scientific materials, and technical support. , ...
Cached Biology Technology:New Product Versions from Neurotechnology Enable Tri-modal Biometrics 2New Product Versions from Neurotechnology Enable Tri-modal Biometrics 3Engageon Releases First Peer-to-Peer Medical Association Social Network 2Advanced Instruments Introduces Next-Generation Web Site 2