Navigation Links
Blood signatures to diagnose infection
Date:9/6/2010

Coughing and wheezing patients could someday benefit from quicker, more accurate diagnosis and treatment for respiratory infections such as flu, through a simple blood test, according to scientists.

Dr. Aimee Zaas, presenting her work at the Society for General Microbiology's autumn meeting in Nottingham describes how simply looking at an individuals blood 'signature' can be used to quickly diagnose and treat ill patients and could even predict the onset of a pandemic.

The team, from the Duke Institute for Genome Sciences & Policy and Duke University Medical Center in the US, looked at the blood of otherwise healthy individuals who had been exposed to rhinovirus, respiratory syncytial virus or influenza. The team found each viral infection stimulated the body to produce a very specific set of immune molecules that could be detected in the blood. Recording the distinct blood signatures for each virus in a database and matching them against blood samples from other ill patients pinpointed the cause of disease with more than 95% accuracy.

Respiratory infections, including colds and flu are a common reason for seeking medical help. As Dr. Zaas highlighted, "Current methods for accurate diagnosis are time and labour intensive and are not always accurate. This means GPs are sometimes overcautious and may prescribe antibiotics unnecessarily, for viral infections. During a pandemic, this has real consequences as there is an increased risk of spreading infection."

Dr. Zaas explained how her test works completely differently to current diagnostic tests as it analyses each individual's immune response to infection, rather than the actual micro-organism responsible. "We effectively look at the imprint in the blood that the virus makes, which is as individual as a signature," she said. "Not only is this much more accurate than traditional testing, it also works much faster as it can be done through a simple blood test."

This work was sponsored by the US Defense Department Advanced Research Projects Agency and is part of a large team effort. If developed further, the findings could be used in emergency departments and primary care clinics to diagnose respiratory viral illness. "This could allow patients quicker access to antiviral drugs, but could also give an accurate warning of an upcoming pandemic," explained Dr. Zaas.


'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert

Related biology news :

1. Scientist plans to test for blood pressure genes affected by age
2. Discovery of natural compounds that could slow blood vessel growth
3. New blood test for Down syndrome
4. On the trail of a targeted therapy for blood cancers
5. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
6. Building the blood-brain barrier
7. Apelin hormone injections powerfully lower blood sugar
8. Battling bacteria in the blood: Researchers tackle deadly infections
9. Femtomolar optical tweezers may enable sensitive blood tests
10. Drops in blood oxygen levels may be key to sudden death in some epilepsy patients
11. Scripps research scientists identify blood component that turns bacteria virulent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/9/2016)... , UAE, May 9, 2016 ... it comes to expanding freedom for high net worth ... Even in today,s globally connected world, there is still ... system could ever duplicate sealing your deal with a ... second passports by taking advantage of citizenship via investment ...
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
(Date:4/13/2016)... CHICAGO , April 13, 2016  IMPOWER physicians ... are setting a new clinical standard in telehealth ... By leveraging the higi platform, IMPOWER patients can ... weight, pulse and body mass index, and, when they ... quick and convenient visit to a local retail location ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... May 25, 2016 , ... Founder of the ... in surgery and surgery of the hand by the National Board of Physicians ... going above and beyond in his pursuit of providing the most comprehensive, effective ...
(Date:5/25/2016)... ... May 25, 2016 , ... Biohaven Pharmaceutical ... (FDA) has granted the company’s orphan drug designation request covering BHV-4157 for the ... granted by the FDA. , Spinocerebellar ataxia is a rare, debilitating neurodegenerative ...
(Date:5/23/2016)... ... 2016 , ... The need for blood donations in South Texas and across the nation is ... & Tissue Center, blood donations are on the decline. In fact, donations across the country ... percent in South Texas in the last four years alone. , There is no substitute ...
(Date:5/23/2016)... Carolina (PRWEB) , ... May 23, 2016 , ... ... and building management solutions and services based in Aurora, Ohio, has broken ground ... established business in the Research Triangle Park area, this new location solidifies a ...
Breaking Biology Technology: