Navigation Links
Blood signatures to diagnose infection
Date:9/6/2010

Coughing and wheezing patients could someday benefit from quicker, more accurate diagnosis and treatment for respiratory infections such as flu, through a simple blood test, according to scientists.

Dr. Aimee Zaas, presenting her work at the Society for General Microbiology's autumn meeting in Nottingham describes how simply looking at an individuals blood 'signature' can be used to quickly diagnose and treat ill patients and could even predict the onset of a pandemic.

The team, from the Duke Institute for Genome Sciences & Policy and Duke University Medical Center in the US, looked at the blood of otherwise healthy individuals who had been exposed to rhinovirus, respiratory syncytial virus or influenza. The team found each viral infection stimulated the body to produce a very specific set of immune molecules that could be detected in the blood. Recording the distinct blood signatures for each virus in a database and matching them against blood samples from other ill patients pinpointed the cause of disease with more than 95% accuracy.

Respiratory infections, including colds and flu are a common reason for seeking medical help. As Dr. Zaas highlighted, "Current methods for accurate diagnosis are time and labour intensive and are not always accurate. This means GPs are sometimes overcautious and may prescribe antibiotics unnecessarily, for viral infections. During a pandemic, this has real consequences as there is an increased risk of spreading infection."

Dr. Zaas explained how her test works completely differently to current diagnostic tests as it analyses each individual's immune response to infection, rather than the actual micro-organism responsible. "We effectively look at the imprint in the blood that the virus makes, which is as individual as a signature," she said. "Not only is this much more accurate than traditional testing, it also works much faster as it can be done through a simple blood test."

This work was sponsored by the US Defense Department Advanced Research Projects Agency and is part of a large team effort. If developed further, the findings could be used in emergency departments and primary care clinics to diagnose respiratory viral illness. "This could allow patients quicker access to antiviral drugs, but could also give an accurate warning of an upcoming pandemic," explained Dr. Zaas.


'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert

Related biology news :

1. Scientist plans to test for blood pressure genes affected by age
2. Discovery of natural compounds that could slow blood vessel growth
3. New blood test for Down syndrome
4. On the trail of a targeted therapy for blood cancers
5. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
6. Building the blood-brain barrier
7. Apelin hormone injections powerfully lower blood sugar
8. Battling bacteria in the blood: Researchers tackle deadly infections
9. Femtomolar optical tweezers may enable sensitive blood tests
10. Drops in blood oxygen levels may be key to sudden death in some epilepsy patients
11. Scripps research scientists identify blood component that turns bacteria virulent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... , June 22, 2016 On Monday, ... call to industry to share solutions for the Biometric ... U.S. Customs and Border Protection (CBP), explains that CBP ... are departing the United States , ... and to defeat imposters. Logo - ...
(Date:6/16/2016)... 16, 2016 The global ... to reach USD 1.83 billion by 2024, according ... Inc. Technological proliferation and increasing demand in commercial ... to drive the market growth.      ... The development of advanced multimodal techniques for biometric ...
(Date:6/9/2016)... , June 9, 2016 ... Police deploy Teleste,s video security solution to ensure the safety ... France during the major tournament Teleste, ... communications systems and services, announced today that its video security ... to back up public safety across the country. ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016   Ginkgo Bioworks , ... industrial engineering, was today awarded as one of ... of the world,s most innovative companies. Ginkgo Bioworks ... for the real world in the nutrition, health ... work directly with customers including Fortune 500 companies ...
(Date:6/24/2016)... Raleigh, NC (PRWEB) , ... June 24, 2016 , ... ... find the most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings ... here to read it now. , Diagnostic biomarkers are signposts in the blood, ...
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)... Prostate Cancer Foundation (PCF) is pleased to announce 24 new Young ... cancer. Members of the Class of 2016 were selected from a pool of ... More About the Class of 2016 PCF Young Investigators ... ... ...
Breaking Biology Technology: