Navigation Links
Blood pressure control system found in kidney's structural units
Date:1/14/2011

SAN ANTONIO (Jan. 14, 2010) The kidney is made up of roughly 1 million working units called nephrons. These basic structural units remove waste products from the blood, recycle some substances to be reused and eliminate what is left as urine. The end segment of nephrons, called the distal nephron, helps set blood pressure by controlling the amount of sodium in our blood.

Today scientists at The University of Texas Health Science Center San Antonio reported how this essential function of the distal nephron is regulated. They demonstrated that sodium handling by the distal nephron is under the control of a local regulatory system.

Loss or dysfunction of this system leads to hypertension resulting from improper salt retention by the kidneys, the scientists found in mouse studies.

"These studies provide the first unequivocal evidence of a blood pressure control system in the distal nephron of the kidney," said senior author James Stockand, Ph.D., professor of physiology at the Health Science Center. "It turns out control of sodium re-absorption by this system is as important to normal blood pressure regulation as is a better-understood system, called the renin-angiotensin-aldosterone system, which works outside the kidney."

Many medications that treat high blood pressure target salt handling in the kidney. "Our work identifies a possible new therapeutic target," Dr. Stockand said.


'/>"/>

Contact: Will Sansom
sansom@uthscsa.edu
210-567-2579
University of Texas Health Science Center at San Antonio
Source:Eurekalert  

Page: 1

Related biology news :

1. Scientist plans to test for blood pressure genes affected by age
2. Discovery of natural compounds that could slow blood vessel growth
3. New blood test for Down syndrome
4. On the trail of a targeted therapy for blood cancers
5. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
6. Building the blood-brain barrier
7. Apelin hormone injections powerfully lower blood sugar
8. Battling bacteria in the blood: Researchers tackle deadly infections
9. Femtomolar optical tweezers may enable sensitive blood tests
10. Drops in blood oxygen levels may be key to sudden death in some epilepsy patients
11. Scripps research scientists identify blood component that turns bacteria virulent
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Blood pressure control system found in kidney's structural units
(Date:4/11/2017)... 11, 2017 No two people are ... the New York University Tandon School of Engineering ... found that partial similarities between prints are common ... mobile phones and other electronic devices can be ... vulnerability lies in the fact that fingerprint-based authentication ...
(Date:4/5/2017)... SEATTLE , April 5, 2017  The Allen ... the Allen Cell Explorer: a one-of-a-kind portal and dynamic ... large-scale 3D imaging data, the first application of deep ... edited human stem cell lines and a growing suite ... the platform for these and future publicly available resources ...
(Date:4/4/2017)... 4, 2017   EyeLock LLC , a leader ... United States Patent and Trademark Office (USPTO) has issued ... linking of an iris image with a face image ... the company,s 45 th issued patent. ... timely given the multi-modal biometric capabilities that have recently ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... business process optimization firm for the life sciences and healthcare industries, announces a ... in San Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” ...
(Date:10/9/2017)...  BioTech Holdings announced today identification and patenting ... stem cell therapy prevents limb loss in animal ... that treatment with ProCell resulted in more than ... to standard bone marrow stem cell administration.  Interestingly, ... of therapeutic effect.  ...
(Date:10/9/2017)... ... 09, 2017 , ... At its national board meeting in North Carolina, ... University’s Departments of Physics and Astronomy, has been selected for membership in ARCS ... for the 2015 Breakthrough Prize in Fundamental physics for the discovery of the accelerating ...
(Date:10/9/2017)... Texas (PRWEB) , ... October ... ... study published on October 5, 2017, in the medical journal, Epilepsia, Brain ... with the gold standard, video EEG, in detecting generalized tonic-clonic seizures (GTCS) ...
Breaking Biology Technology: