Navigation Links
Blood 'fingerprints' for cancer
Date:9/3/2008

Serum microRNAs (miRNAs) can serve as biomarkers for the detection of diseases including cancer and diabetes, according to research published online this week in Cell Research. The findings pave the way for a revolutionary non-invasive diagnostic tool.

miRNAs are a class of naturally occurring small non-coding RNAs that have been linked with cancer development. Recent studies reporting individual miRNAs as diagnostic biomarkers of specific cancers were unable to rule out the possibility that these miRNAs appeared as a result of contamination.

Chen-Yu Zhang and colleagues are the first to comprehensively characterize entire blood miRNA profiles of healthy subjects and patients with lung cancer, colorectal cancer and diabetes, ruling out contamination. They propose that the specific serum miRNA expression profiles they identified constitute fingerprints for cancer and disease.

Although tumour markers greatly improve diagnosis, current diagnostic techniques are prohibitively invasive and therefore have limited clinical application. The new approach is non-invasive and has the potential to transform the clinical management of various cancers and diseases through improving disease diagnosis, cancer classification, prognosis estimation, prediction of therapeutic efficacy, maintenance of surveillance following surgery, and the ability to forecast disease recurrence. The new technique will also be useful to pharmacological companies in identifying population subgroups who are responsive to drugs that have failed in phase III clinical trials.


'/>"/>

Contact: Chen-Yu Zhang
cyzhang@nju.edu.cn
86-258-368-6234
Nanjing University School of Life Sciences
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers devise means to create blood by identifying earliest stem cells
2. Researchers link cocoa flavanols to improved brain blood flow
3. Blood pressure response to daily stress provides clues for better hypertension treatment
4. People with heart disease still have trouble controlling blood lipid levels
5. OSU study shows exposure to bad air raises blood pressure
6. Vitamin A pushes breast cancer to form blood vessel cells
7. Mobilizing white blood cells to the lung: New discovery could lead to an improved influenza vaccine
8. Counting tumor cells in blood predicts treatment benefit in prostate cancer
9. New technology enhances therapeutic potential of cord blood stem cells
10. Natural compounds in cocoa tied to blood flow improvements for adults with type 2 diabetes
11. New cell-based sensors sniff out danger like bloodhounds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/4/2017)... --  EyeLock LLC , a leader of iris-based identity ... and Trademark Office (USPTO) has issued U.S. Patent No. ... iris image with a face image acquired in sequence ... th issued patent. "The issuance ... multi-modal biometric capabilities that have recently come to market ...
(Date:3/30/2017)... March 30, 2017 The research team of ... three-dimensional (3D) fingerprint identification by adopting ground breaking 3D fingerprint minutiae ... realm of speed and accuracy for use in identification, crime investigation, ... cost. ... A research ...
(Date:3/28/2017)... , March 28, 2017 ... Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video ... and Region - Global Forecast to 2022", published by ... in 2016 and is projected to reach USD 75.64 ... 2017 and 2022. The base year considered for the ...
Breaking Biology News(10 mins):
(Date:5/22/2017)... ... May 22, 2017 , ... Cancer ... exhibiting in booth B2 at the Association for Pathology Informatics Annual Summit ... In addition to demonstrating its Cancer Diagnostic Cockpit and Consultation Portal, Inspirata will ...
(Date:5/19/2017)... ... May 19, 2017 , ... In response to the strong base ... Medical Systems, Inc. announces the release of their Gait Trainer 3 with an Integrated ... a biomedical system to aid in rehabilitating individuals with cerebral palsy, traumatic brain injury, ...
(Date:5/18/2017)... ... May 18, 2017 , ... Lajollacooks4u has added another option ... two-hour team-building package designed for groups of 10-30 people. Guests can choose ... items, such as Blackened Shrimp with Edamame Salad, Pizza Rolls with Pepperoni and ...
(Date:5/18/2017)... , ... May 17, 2017 ... ... standards with psychonneuroendocrine stress expertise, and further enhances its scientific power by ... Douglas A. Granger, Ph.D., has agreed to join the scientific advisory board. ...
Breaking Biology Technology: