Navigation Links
Bleeding, not inflammation, is major cause of early lung infection death
Date:8/27/2007

Researchers believe they have discovered why a bacterial lung infection is so lethal in the early stages, and its not what medical authorities had thought, according to research published August 23 in the journal Immunity. The study reveals for the first time that a toxin released by bacteria causes severe bleeding in the lungs by patients with pneumococcal pneumonia. It is the bleeding, the authors argue, not inflammation as once thought, which makes the infections deadly. The same study also reveals why antibiotics often fail to help prevent early death.

Also called pneumococcus, the bacteria Streptococcus pneumoniae infects the upper respiratory tracts of the elderly and young children mostly. There are 500,000 cases of pneumococcal pneumonia annually in the United States, with about 40,000 of them fatal, according to the Centers of Disease Control and Prevention. Those numbers would be worse in children younger than 2 years if not for the 2000 introduction of the pneumococcal vaccine (Prevnar), according to one report. The picture remains far more serious outside of the United States, however, where pneumococcal infections take the lives of at least one million children each year, according to the World Health Organization

Our finding provides a better understanding of what makes a major global bacterial infection deadly, and marks the beginning of realistic efforts to save lives worldwide, said Jian-Dong Li, M.D., Ph.D., professor of Microbiology & Immunology at the University of Rochester Medical Center and an author on the Immunity paper. The power of understanding this mechanism is that it not only suggests how better to treat this disease, but also that we should think twice about whether standard drug treatments are doing more harm than good, said Li, also senior and corresponding author on the paper.

A Medical Mystery

Recognizing molecules as self, versus foreign invaders to be labeled for destruction, is
'/>"/>

Contact: Greg Williams
Greg_Williams@urmc.rochester.edu
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Columbia research lifts major hurdle to gene therapy for cancer
2. Researchers uncover sequence of major rice pathogen
3. Emergence of cancer as major cause of childhood death in developing countries is not being adequately addressed
4. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
5. Virologists make major step towards understanding the process of HIV infection
6. Major new UNC-based drinking water study suggests pregnancy fears may be overstated
7. Major breakthrough in the treatment of cancers and infectious diseases
8. Major advance made on DNA structure
9. Major link in brain-obesity puzzle found
10. Biota makes major antiviral discovery
11. New gene scanning technology marks a major advance in disease research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... NEW YORK , Aug. 27, 2014 /PRNewswire/ ... report is available in its catalogue: ... http://www.reportlinker.com/p02316674/Law-Enforcement-Biometrics-Market-in-North-America-2014-2018.html ... to assess individuals on the basis of their ... and identification of both physiological traits such as ...
(Date:8/27/2014)... PITTSBURGHLearning a new skill is easier when it is ... a trained pianist might learn a new melody more ... , Neural engineers from the Center for the Neural ... of Pittsburgh and Carnegie Mellon Universityhave discovered a fundamental ... happens. Published as the cover story in the Aug. ...
(Date:8/27/2014)... the greatest risk to Europe based upon a proxy ... researchers using a ,big data, approach to scientific research. ... and Global Health ranked the top 100 pathogens affecting ... a system which, they believe, will help governments across ... of infectious diseases, including as a result of climate ...
Breaking Biology News(10 mins):Law Enforcement Biometrics Market in North America 2014-2018 2Law Enforcement Biometrics Market in North America 2014-2018 3Law Enforcement Biometrics Market in North America 2014-2018 4Law Enforcement Biometrics Market in North America 2014-2018 5Pitt and Carnegie Mellon engineers discover why learning can be difficult 2Pitt and Carnegie Mellon engineers discover why learning can be difficult 3Big data approach identifies Europe's most dangerous human and domestic animal pathogens 2
... as 50 percent of all human protein-coding genes are ... onset and progression of cancer, others can actually suppress ... cancer therapy. They can also serve as potential biomarkers ... Cancer Biomarkers , investigators report on non-coding miRNAs ...
... have created stunning images of the branching patterns of individual ... eLife on Dec. 18, details the arrangement of ... branching patterns define ten distinct groups that, the researchers say, ... could hold clues for pain management and other areas of ...
... inexpensive new source of a widely used chemical for plastics, ... Succinic acid, traditionally drawn from petroleum, is one focus of ... 2004, the Department of Energy named succinic acid one of ... biological means and turned into high-value materials. Several ...
Cached Biology News:MicroRNAs present exciting opportunities for cancer therapy and diagnosis 2MicroRNAs present exciting opportunities for cancer therapy and diagnosis 3Why our backs can't read braille 2Why our backs can't read braille 3Soybeans a source of valuable chemical 2
(Date:8/27/2014)... 2014 “We are honored to be ... Ven Thangaraj, CEO of Radiant Sage. “We are offering ... the imaging corelab market to a different level. ... organizations to efficiently and effectively manage the massive amounts ... be analyzed and read by trained physicians. Being recognized ...
(Date:8/27/2014)... , Aug. 27, 2014 Research and ... "Global Enzyme for Pulp & Paper Industry Report 2014" ... Global Enzyme for Pulp & Paper Industry Report 2014 ... state of the global enzyme for pulp & paper ... of the industry including definitions, classifications, applications and industry ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 Riviera ... is announcing the creation of the Sancilio Scientific ... take the SCI’s philosophy of looking to nature ... and development actions are based on sound scientific ... Scientific Advisory Board provides a vehicle for SCI ...
(Date:8/27/2014)... August 27, 2014 Remcom announces an ... with new features for the biomedical industry. The ... Biological Thermal Sensor, exclusive to the Bio-Pro version of ... of XFdtd, developed to calculate the biological effects of ... been added to all versions to expand engineers’ post-processing ...
Breaking Biology Technology:Radiant Sage Named to CIOReview List of 100 Most Promising Technology Companies 2Global Enzyme for Pulp & Paper Industry Report 2014 2New Sancilio & Company, Inc. Scientific Board 2New Sancilio & Company, Inc. Scientific Board 3Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 2Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 3
... attract the presence of major pharmaceutical companies from out ... own environment, said a panel assembled Monday night by ... building the future today in Wisconsin has to do ... CEO Irene Hrusovsky. , ,Woody Hydrick, a senior consultant ...
... the next ten years, according to a proposal that has ... Senate for a vote this month. State Senator Joe Leibham, ... that would be regulated similarly to airports. , ,Leibhams bill, ... private space travel in the area, receive any potential federal ...
... the lineup for DEMO 2006 nears, Ive had plenty of ... launch. , ,Does a product in "beta" variously defined ... qualify as launch-ready? Must I have customers in the queue ... a shipping product that we've only talked about with our ...
Cached Biology Technology:Panel stresses drawing outside biotech firms to state 2Space port could open in Sheboygan in next 10 years 2Space port could open in Sheboygan in next 10 years 3When do you go from "beta" to "product launch"? 2When do you go from "beta" to "product launch"? 3
... in heart tissues, and is produced ... conditions. Treatment of cells with ... TIMP-4 in some cell types, but ... require concentration of cell culture media ...
Goat polyclonal to HSPC150 ( Abpromise for all tested applications). entrezGeneID: 29089...
Anti-MMP-13 Collagenase-3, amino terminal end of active enzyme; rabbit host...
...
Biology Products: