Navigation Links
Blame your parents for bunion woes
Date:5/19/2013

A novel study reports that white men and women of European descent inherit common foot disorders, such as bunions (hallux valgus) and lesser toe deformities, including hammer or claw toe. Findings from the Framingham Foot Studythe first to estimate the heritability of foot disorders in humansappear in Arthritis Care & Research, a journal published by Wiley on behalf of the American College of Rheumatology (ACR).

Previous studies show that as many as 60% of older adults have foot disorders which may limit mobility and reduce their quality of life. In fact, bunions affect 23% of individuals 18 to 65 years of age and 36% of those over 65 years according to a study by Nix et al. While experts suggest that women, older adults and those with a higher body mass index (BMI) are at greater risk for foot disorders, there is little understanding of the genetics involved in their development.

The study, led by Arthritis Care & Research Editor-in-Chief, Dr. Marian Hannan from Hebrew SeniorLife and Harvard Medical School in Boston, Mass, included 1,370 participants enrolled in the Framingham Foot Study. Participants had a mean age of 66 years and 57% were female. Foot exams to identify hallux valgus, lesser toe deformities and plantar soft tissue atrophy were conducted between 2002 and 2008. The team estimated heritability using software that performs genetic analyses of familial data (pedigree structures).

Results show the prevalence of bunions, lesser toe deformities and plantar soft tissue atrophy was 31%, 30% and 28%, respectively. Hallux valgus and lesser toe deformity, two of the most common structural foot disorders that affect up to half of older adults in the U.S. and Europe, were found to be highly heritable depending on age and sex. The team reports that plantar soft tissue atrophy did not demonstrate significant heritability in the study cohort.

"Our study is the largest investigation of the heritability of common foot disorders in older adults, confirming that bunions and lesser toe deformities are highly inheritable in Caucasian men and women of European descent," concludes Dr. Hannan. "These new findings highlight the importance of furthering our understanding of what causes greater susceptibility to these foot conditions, as knowing more about the pathway may ultimately lead to early prevention or early treatment."


'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Related biology news :

1. Gene sequencing project finds new mutations to blame for a majority of brain tumor subtype
2. Scientists conclude high fructose corn syrup should not be blamed for obesity
3. Viruses not to blame for chronic fatigue syndrome after all
4. Sick from stress? Blame your mom… and epigenetics
5. CU-Boulder study looks at microbial differences between parents, kids and dogs
6. Disappearing nannies force parents to accept their duties
7. Environment schemes for kids influence parents behavior
8. Parents talking to their teens about being overweight
9. Questionnaire completed by parents may help identify 1-year-olds at risk for autism
10. Parents seen as critical stakeholders in expanding newborn screening
11. Parents say that healthy eating is challenging for youth who play sports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2017)... 18, 2017  Socionext Inc., a global expert in SoC-based imaging ... server, the M820, which features the company,s hybrid codec technology. A ... Tera Probe, Inc., will be showcased during the upcoming Medtec Japan ... at the Las Vegas Convention Center April ... Click here for ...
(Date:4/13/2017)... According to a new market research report "Consumer IAM Market by ... Service, Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast to ... USD 14.30 Billion in 2017 to USD 31.75 Billion by 2022, at ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... 11, 2017 No two people are ... the New York University Tandon School of Engineering ... found that partial similarities between prints are common ... mobile phones and other electronic devices can be ... vulnerability lies in the fact that fingerprint-based authentication ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... ... June 22, 2017 , ... Ovation Fertility supports the American ... bringing new hope for prospective parents who are challenged with costs of treatment. ... World Health Organization’s designation in hopes of changing the way health insurers, governments ...
(Date:6/22/2017)... ... June 22, 2017 , ... RURO, Inc., a ... version 6.5, a content-packed update to the Limfinity® framework. , LimitLIS® and other ... more diverse base of customers among labs and other businesses. Limfinity® 6.5 adds ...
(Date:6/20/2017)... ... 20, 2017 , ... HorizonScan is providing food and ingredient ... likely threat to their products at the annual IFT conference in Las Vegas, ... expo attracts over 20,000 attendees representing food science professionals from over 90 countries ...
(Date:6/20/2017)... ... June 20, 2017 , ... GigaGen Inc ., ... immune repertoires, announces launch of its new Surge(TM) Discovery service at ... of GigaGen, will present on Surge at the conference. , Surge is the ...
Breaking Biology Technology: