Navigation Links
Bitter orange SRMs: Tools for product analysis/quality
Date:5/16/2008

The National Institute of Standards and Technology (NIST) has developed Standard Reference Materials (SRMs) for bitter orange, long used in folk medicine and now increasingly used in herbal weight-loss products. Researchers can use the new materials to develop and test analytical methods for compounds in bitter orange, or as control materials for quality assurance of their measurements. The NIST samples do not offer scientific evidence to address the use of bitter orange for health purposes.

Also known as Seville orange, sour orange, and Zhi shi, bitter orange has been used in traditional Chinese medicine and by indigenous people of the Amazon rain forest for nausea, indigestion and constipation. Current uses of bitter orange are for heartburn, loss of appetite, nasal congestion and weight loss. Users also apply it to skin for fungal infections such as ringworm and athletes foot.

Bitter orange has been used as a substitute for ephedra, a dietary supplement for weight loss now banned by the U.S. Food and Drug Administration (FDA). The dried fruit and peel of bitter orange (and sometimes the flowers and leaves) are taken by mouth in extracts, tablets and capsules. Bitter orange oil also can be applied to the skin. NIST supplies standardized samples of bitter orange in three forms that represent different analytical measurement challenges: ground fruit, extract and solid oral dosage form (tablets).

The National Institute of Healths (NIH) National Center for Complementary and Alternative Medicine (NCCAM) affirms that there is not enough scientific evidence to support the use of bitter orange for health purposes. It notes many herbal weight-loss products now use bitter orange peel in place of ephedra. However, bitter orange contains the chemical synephrine, which is similar to the main chemical in ephedra. The U.S. FDA banned ephedra because it raises blood pressure and is linked to heart attacks and strokes: it is unclear whether bitter orange has similar effects. There is currently little evidence that bitter orange is safer to use than ephedra.

The new bitter orange reference materials include SRM 3258 (ground fruit), SRM 3259 (extract) and SRM 3260 (solid oral dosage form). In addition the three SRMs are packaged together as SRM 3261. The SRM materials for analysis and measurement come with certified concentration values for synephrine, octopamine, tyramine, N-methylytramine, hordenine, total alkaloids and caffeine.


'/>"/>

Contact: John Blair
john.blair@nist.gov
301-975-4261
National Institute of Standards and Technology (NIST)
Source:Eurekalert

Related biology news :

1. Introducing Orange Bulldog
2. Ginkgo SRMs: Tools for product analysis/quality
3. Research leading to tools for managing bovine respiratory disease complex
4. Positron emission tomography superior to standard evaluation tools in measuring treatment response
5. Smithsonian study: Sediment prediction tools off the mark
6. Building the future -- 21st century nano tools to repair the nervous system
7. NAS report offers new tools to assess health risks from chemicals
8. Interacting protein theory awaits test from new neutron analysis tools
9. New caledonian crows find 2 tools better than 1
10. New study links fate of personal care products to environmental pollution and human health concerns
11. bioMETRX, Inc. Introduces New Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/18/2016)... --> --> Competitive Landscape Analysis ... Physical infrastructure and Perimeter Surveillance & Detection Systems ... and the continuing migration crisis in the Middle ... led visiongain to publish this unique report, which is crucial ... & security companies in the border security market and the ...
(Date:3/14/2016)... , Allemagne, March 14, 2016 ... http://www.apimages.com ) - --> - Renvoi : ... - --> --> ... solutions biométriques, fournit de nouveaux lecteurs d,empreintes digitales ... LF10 de DERMALOG sera utilisé pour produire des ...
(Date:3/9/2016)... March 9, 2016 This BCC Research report ... of the RNA Sequencing (RNA Seq) market for the ... instruments, tools and reagents, data analysis, and services. ... of the RNA-Sequencing market such as RNA-Sequencing tools and ... main factors affecting each segment and forecast their market ...
Breaking Biology News(10 mins):
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... Summit for ... to support the development of a patient-specific stem cell therapy for the treatment of ... lab of Dr. Jeanne Loring at The Scripps Research Institute in San Diego, CA. ...
(Date:4/29/2016)... April 29, 2016 Elekta is ... update to its industry-leading treatment planning software, is available ... Monaco version 5.11 provides significant performance ... calculation speeds up to four times faster than in ... the industry,s gold standard Monte Carlo ...
(Date:4/28/2016)... NEW YORK , April 28, 2016 /PRNewswire/ ... biotechnology acceleration company reports the Company,s CEO  was ... capital titled Accelerators Enter When VCs Fear To ... Life Science Leader magazine is an ... work for everything from emerging biotechs to Big ...
(Date:4/28/2016)... ... April 28, 2016 , ... Next week on May ... its first-in-class technologies for tissue stem cell counting and expansion to gene-editing scientists ... Reprogramming & CRISPR-based Genome Engineering in Burlington, Massachusetts. , The attention of most ...
Breaking Biology Technology: