Navigation Links
Bitter orange SRMs: Tools for product analysis/quality
Date:5/16/2008

The National Institute of Standards and Technology (NIST) has developed Standard Reference Materials (SRMs) for bitter orange, long used in folk medicine and now increasingly used in herbal weight-loss products. Researchers can use the new materials to develop and test analytical methods for compounds in bitter orange, or as control materials for quality assurance of their measurements. The NIST samples do not offer scientific evidence to address the use of bitter orange for health purposes.

Also known as Seville orange, sour orange, and Zhi shi, bitter orange has been used in traditional Chinese medicine and by indigenous people of the Amazon rain forest for nausea, indigestion and constipation. Current uses of bitter orange are for heartburn, loss of appetite, nasal congestion and weight loss. Users also apply it to skin for fungal infections such as ringworm and athletes foot.

Bitter orange has been used as a substitute for ephedra, a dietary supplement for weight loss now banned by the U.S. Food and Drug Administration (FDA). The dried fruit and peel of bitter orange (and sometimes the flowers and leaves) are taken by mouth in extracts, tablets and capsules. Bitter orange oil also can be applied to the skin. NIST supplies standardized samples of bitter orange in three forms that represent different analytical measurement challenges: ground fruit, extract and solid oral dosage form (tablets).

The National Institute of Healths (NIH) National Center for Complementary and Alternative Medicine (NCCAM) affirms that there is not enough scientific evidence to support the use of bitter orange for health purposes. It notes many herbal weight-loss products now use bitter orange peel in place of ephedra. However, bitter orange contains the chemical synephrine, which is similar to the main chemical in ephedra. The U.S. FDA banned ephedra because it raises blood pressure and is linked to heart attacks and strokes: it is unclear whether bitter orange has similar effects. There is currently little evidence that bitter orange is safer to use than ephedra.

The new bitter orange reference materials include SRM 3258 (ground fruit), SRM 3259 (extract) and SRM 3260 (solid oral dosage form). In addition the three SRMs are packaged together as SRM 3261. The SRM materials for analysis and measurement come with certified concentration values for synephrine, octopamine, tyramine, N-methylytramine, hordenine, total alkaloids and caffeine.


'/>"/>

Contact: John Blair
john.blair@nist.gov
301-975-4261
National Institute of Standards and Technology (NIST)
Source:Eurekalert

Related biology news :

1. Introducing Orange Bulldog
2. Ginkgo SRMs: Tools for product analysis/quality
3. Research leading to tools for managing bovine respiratory disease complex
4. Positron emission tomography superior to standard evaluation tools in measuring treatment response
5. Smithsonian study: Sediment prediction tools off the mark
6. Building the future -- 21st century nano tools to repair the nervous system
7. NAS report offers new tools to assess health risks from chemicals
8. Interacting protein theory awaits test from new neutron analysis tools
9. New caledonian crows find 2 tools better than 1
10. New study links fate of personal care products to environmental pollution and human health concerns
11. bioMETRX, Inc. Introduces New Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... No two people are believed to ... York University Tandon School of Engineering and Michigan ... partial similarities between prints are common enough that ... and other electronic devices can be more vulnerable ... in the fact that fingerprint-based authentication systems feature ...
(Date:4/5/2017)...  The Allen Institute for Cell Science today announces ... portal and dynamic digital window into the human cell. ... application of deep learning to create predictive models of ... a growing suite of powerful tools. The Allen Cell ... publicly available resources created and shared by the Allen ...
(Date:4/4/2017)... April 4, 2017   EyeLock LLC , a ... the United States Patent and Trademark Office (USPTO) has ... the linking of an iris image with a face ... represents the company,s 45 th issued patent. ... very timely given the multi-modal biometric capabilities that have ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... They call it the ... network, a depiction of a system of linkages and connections so complex and ... professor of computer science at Worcester Polytechnic Institute (WPI) and director of the ...
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, a global contract research, ... improve patient outcomes and quality of life, will now be offering its impurity ... to new regulatory requirements for all new drug products, including the finalization of ...
(Date:10/11/2017)... Alto, CA, USA (PRWEB) , ... October 11, 2017 , ... ... set to take place on 7th and 8th June 2018 in San Francisco, CA. ... policy influencers as well as several distinguished CEOs, board directors and government officials from ...
(Date:10/11/2017)... ... 2017 , ... A new study published in Fertility and ... in vitro fertilization (IVF) transfer cycles. The multi-center matched cohort study ... comparing the results from the fresh and frozen transfer cohorts, the authors of ...
Breaking Biology Technology: