Navigation Links
Bitter orange SRMs: Tools for product analysis/quality
Date:5/16/2008

The National Institute of Standards and Technology (NIST) has developed Standard Reference Materials (SRMs) for bitter orange, long used in folk medicine and now increasingly used in herbal weight-loss products. Researchers can use the new materials to develop and test analytical methods for compounds in bitter orange, or as control materials for quality assurance of their measurements. The NIST samples do not offer scientific evidence to address the use of bitter orange for health purposes.

Also known as Seville orange, sour orange, and Zhi shi, bitter orange has been used in traditional Chinese medicine and by indigenous people of the Amazon rain forest for nausea, indigestion and constipation. Current uses of bitter orange are for heartburn, loss of appetite, nasal congestion and weight loss. Users also apply it to skin for fungal infections such as ringworm and athletes foot.

Bitter orange has been used as a substitute for ephedra, a dietary supplement for weight loss now banned by the U.S. Food and Drug Administration (FDA). The dried fruit and peel of bitter orange (and sometimes the flowers and leaves) are taken by mouth in extracts, tablets and capsules. Bitter orange oil also can be applied to the skin. NIST supplies standardized samples of bitter orange in three forms that represent different analytical measurement challenges: ground fruit, extract and solid oral dosage form (tablets).

The National Institute of Healths (NIH) National Center for Complementary and Alternative Medicine (NCCAM) affirms that there is not enough scientific evidence to support the use of bitter orange for health purposes. It notes many herbal weight-loss products now use bitter orange peel in place of ephedra. However, bitter orange contains the chemical synephrine, which is similar to the main chemical in ephedra. The U.S. FDA banned ephedra because it raises blood pressure and is linked to heart attacks and strokes: it is unclear whether bitter orange has similar effects. There is currently little evidence that bitter orange is safer to use than ephedra.

The new bitter orange reference materials include SRM 3258 (ground fruit), SRM 3259 (extract) and SRM 3260 (solid oral dosage form). In addition the three SRMs are packaged together as SRM 3261. The SRM materials for analysis and measurement come with certified concentration values for synephrine, octopamine, tyramine, N-methylytramine, hordenine, total alkaloids and caffeine.


'/>"/>

Contact: John Blair
john.blair@nist.gov
301-975-4261
National Institute of Standards and Technology (NIST)
Source:Eurekalert

Related biology news :

1. Introducing Orange Bulldog
2. Ginkgo SRMs: Tools for product analysis/quality
3. Research leading to tools for managing bovine respiratory disease complex
4. Positron emission tomography superior to standard evaluation tools in measuring treatment response
5. Smithsonian study: Sediment prediction tools off the mark
6. Building the future -- 21st century nano tools to repair the nervous system
7. NAS report offers new tools to assess health risks from chemicals
8. Interacting protein theory awaits test from new neutron analysis tools
9. New caledonian crows find 2 tools better than 1
10. New study links fate of personal care products to environmental pollution and human health concerns
11. bioMETRX, Inc. Introduces New Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/3/2016)... , Feb. 3, 2016 ... the addition of the "Emotion Detection ... Machine Learning, and Others), Software Tools (Facial ... Areas, End Users,and Regions - Global forecast ... --> http://www.researchandmarkets.com/research/d8zjcd/emotion_detection ) has ...
(Date:2/2/2016)... Va. , Feb. 2, 2016   ... award from the U.S. Army Research Office and ... the range and sensitivity of the company,s ... Past Accounting Mission and, more generally, defense-related DNA ... DNA phenotyping capabilities (predicting appearance and ancestry from ...
(Date:1/28/2016)... 2016 Synaptics (NASDAQ: SYNA ), a leading developer ... quarter ended December 31, 2015. --> ... 2016 increased 2 percent compared to the comparable quarter last year ... 2016 was $35.0 million, or $0.93 per diluted share. ... the first quarter of fiscal 2016 grew 9 percent over the ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... , Feb. 10, 2016 NX Prenatal ... its proprietary NeXosome® technology for early warning of ... its most recent study by Dr. Thomas ... the Society for Maternal Fetal Medicine,s (SMFM) annual meeting ... 1-6 th , 2016.  The presentation reported initial ...
(Date:2/10/2016)... 10, 2016  Matchbook, Inc., a company specializing ... biotech companies, announced today the appointment of ... Jim brings nearly 25 years of experience in ... spent nearly two decades in executive level roles ... at Genzyme and, most recently headed global logistics ...
(Date:2/10/2016)... ... February 10, 2016 , ... PatientCrossroads announces that ... secure online PatientCrossroads platform, has exceeded both its one-year and overall recruitment goals ... study, which seeks to advance understanding of the hereditary risks for certain kinds ...
(Date:2/9/2016)... ... February 09, 2016 , ... With a presidential election in ... Care Business Conference will bring together over 500 top healthcare leaders for a night ... transformation. The conference, organized by MBA students of the University of Pennsylvania’s Wharton School, ...
Breaking Biology Technology: