Navigation Links
Bisphenol A affects sex-specific reproductive behaviors in a monogamous animal species
Date:2/11/2013

Parents, teachers and psychologists know boys and girls behave differently. However, that difference isn't taken into account by most methods used to assess the risk to children from chemical exposure, according to Cheryl Rosenfeld, associate professor of biomedical sciences in the University of Missouri's Bond Life Sciences Center. A series of experiments by Rosenfeld studied the effects of prenatal exposure to bisphenol A (BPA) on later reproductive-associated behaviors using a socially and genetically monogamous rodent, the California mouse, which may better mirror most human societies than other rodents.

She observed harmful alterations to behaviors that affect the likelihood of successfully attracting a mate and reproducing. However, developmental exposure to BPA altered the behaviors of males differently than females. In females, BPA reduced exploratory behavior that is essential for them to forage to provide nutritional support to her offspring. In contrast, California mice males exposed to BPA demonstrated reduced territorial marking, which is essential for them to defend a home range and their mate. Rosenfeld suggests that these animal findings might provide a framework to guide human risk assessment studies in the sense that such studies may need to consider that pre- and post-natal exposure to BPA might differentially impact boys' versus girls' behaviors.

The American public comes into daily contact with the chemical bisphenol A (BPA) as it is present in a wide assortment of products, including some types of paper receipts, plastic containers and canned goods, including beer and soda cans. The concern of many scientists is that the chemical can mimic the effect of female hormones in the human body. Studies looking for behavioral effects of BPA in children often focus on expression of general behaviors, such as aggression, anxiety or other traits, but more refined assessments are needed for boys versus girls, according to Rosenfeld.

"We use animal models to provide informative decisions about our own health and the risks associated with BPA," Rosenfeld said. "What we have observed in those models is that BPA affects male rodents differently than females. Risk assessment studies examining the impacts of BPA in humans could be more accurate if they took sex into account when monitoring for changes in children's behavioral patterns."

Rosenfeld's most recent study observed the influence of prenatal BPA exposure on California mice, whereas earlier studies had used deer mice. The two rodent species have contrasting mating behaviors. California mice are monogamous, as opposed to the polygamous deer mice. Although BPA affected the California mice differently than the deer mice, both rodent species' behaviors were altered in ways that would decrease their ability to successfully mate and pass on their genes to future generations. Since two species of rodents with different mating patterns were both affected, it suggests that BPA disrupts essential reproductive-associated behaviors that are species- and sex-specific.


'/>"/>

Contact: Tim Wall
walltj@missouri.edu
573-882-3346
University of Missouri-Columbia
Source:Eurekalert

Related biology news :

1. Dung beetle diversity affects Florida livestock producers
2. Genetically modified corn affects its symbiotic relationship with non-target soil organisms
3. Dartmouth researchers are learning how exercise affects the brain
4. Zebrafish study explains why the circadian rhythm affects your health
5. Study finds how BPA affects gene expression, anxiety; Soy mitigates effects
6. Study reveals how common gene mutation affects kids with autism spectrum disorders
7. Combined pesticide exposure affects bumblebee colony success
8. Stirred not mixed: How seawater turbulence affects marine food webs
9. Worries about dementia how hospitalization affects the elderly
10. Reproductive health providers should discuss environmental exposure risks with patients
11. Highly exposed to phthalates as fetuses, female mice have altered reproductive lives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/6/2017)... March 6, 2017 Mintigo , ... today announced Predictive Sales Coach TM , its ... sales intelligence into Salesforce. This unique AI application ... sales organizations with deep knowledge of their customers ... intelligent engagement. Predictive Sales Coach extends Mintigo,s existing ...
(Date:3/2/2017)... -- Summary This report provides all the ... its partnering interests and activities since 2010. Download ... Partnering Deals and Alliance since 2010 report provides an ... the world,s leading life sciences companies. On ... inclusion of the most up to date deal and ...
(Date:3/2/2017)... Australia , March 2, 2017 Australian ... Ltd (ASX: CYP), has signed an agreement with ... from the Monash Biomedicine Discovery Institute and Department of ... to conduct a further preclinical study to support the ... treatment of asthma.  Asthma is a ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... , March 27, 2017 DarioHealth Corp. (NASDAQ: ... health and big data solutions, today announced that it ... coverage option for U.S. consumers who want to have ... DarioHealth has signed strategic alliance agreements with partners across ... coverage benefits, and if approved, will supply and bill ...
(Date:3/24/2017)... DUBLIN , Mar. 24, 2017 Research ... Stem Cell (hESC) Research - Global Strategic Business Report" report ... ... Cell (hESC) Research in US$ Million. Annual estimates and forecasts are ... are derived from primary and secondary research. The ...
(Date:3/24/2017)... Agenus Inc. (NASDAQ: AGEN), an immuno-oncology company ... vaccines, today announced participation at the following conferences: ... and Maidstone Life Sciences conference "Cancer Immunotherapy Conference" at ... New York, NY . Agenus will participate in ... am: Robert B. Stein , M.D., Ph.D., President, ...
(Date:3/23/2017)... March 23, 2017  Northwest Biotherapeutics (OTCQB: NWBO) ... immune therapies for solid tumor cancers, today announced ... financing it announced last Friday, March 17, 2017. ... institutional investors securities totaling 28,843,692 shares, comprised of ... 10,000,000 shares of Class C Warrants pre-funded at ...
Breaking Biology Technology: