Navigation Links
Bisphenol A affects sex-specific reproductive behaviors in a monogamous animal species

Parents, teachers and psychologists know boys and girls behave differently. However, that difference isn't taken into account by most methods used to assess the risk to children from chemical exposure, according to Cheryl Rosenfeld, associate professor of biomedical sciences in the University of Missouri's Bond Life Sciences Center. A series of experiments by Rosenfeld studied the effects of prenatal exposure to bisphenol A (BPA) on later reproductive-associated behaviors using a socially and genetically monogamous rodent, the California mouse, which may better mirror most human societies than other rodents.

She observed harmful alterations to behaviors that affect the likelihood of successfully attracting a mate and reproducing. However, developmental exposure to BPA altered the behaviors of males differently than females. In females, BPA reduced exploratory behavior that is essential for them to forage to provide nutritional support to her offspring. In contrast, California mice males exposed to BPA demonstrated reduced territorial marking, which is essential for them to defend a home range and their mate. Rosenfeld suggests that these animal findings might provide a framework to guide human risk assessment studies in the sense that such studies may need to consider that pre- and post-natal exposure to BPA might differentially impact boys' versus girls' behaviors.

The American public comes into daily contact with the chemical bisphenol A (BPA) as it is present in a wide assortment of products, including some types of paper receipts, plastic containers and canned goods, including beer and soda cans. The concern of many scientists is that the chemical can mimic the effect of female hormones in the human body. Studies looking for behavioral effects of BPA in children often focus on expression of general behaviors, such as aggression, anxiety or other traits, but more refined assessments are needed for boys versus girls, according to Rosenfeld.

"We use animal models to provide informative decisions about our own health and the risks associated with BPA," Rosenfeld said. "What we have observed in those models is that BPA affects male rodents differently than females. Risk assessment studies examining the impacts of BPA in humans could be more accurate if they took sex into account when monitoring for changes in children's behavioral patterns."

Rosenfeld's most recent study observed the influence of prenatal BPA exposure on California mice, whereas earlier studies had used deer mice. The two rodent species have contrasting mating behaviors. California mice are monogamous, as opposed to the polygamous deer mice. Although BPA affected the California mice differently than the deer mice, both rodent species' behaviors were altered in ways that would decrease their ability to successfully mate and pass on their genes to future generations. Since two species of rodents with different mating patterns were both affected, it suggests that BPA disrupts essential reproductive-associated behaviors that are species- and sex-specific.


Contact: Tim Wall
University of Missouri-Columbia

Related biology news :

1. Dung beetle diversity affects Florida livestock producers
2. Genetically modified corn affects its symbiotic relationship with non-target soil organisms
3. Dartmouth researchers are learning how exercise affects the brain
4. Zebrafish study explains why the circadian rhythm affects your health
5. Study finds how BPA affects gene expression, anxiety; Soy mitigates effects
6. Study reveals how common gene mutation affects kids with autism spectrum disorders
7. Combined pesticide exposure affects bumblebee colony success
8. Stirred not mixed: How seawater turbulence affects marine food webs
9. Worries about dementia how hospitalization affects the elderly
10. Reproductive health providers should discuss environmental exposure risks with patients
11. Highly exposed to phthalates as fetuses, female mice have altered reproductive lives
Post Your Comments:
(Date:6/2/2016)... 2016 The Department of Transport Management ... 44 million US Dollar project, for the , ... Personalization, Enrolment, and IT Infrastructure , to ... and implementation of Identity Management Solutions. Numerous renowned international vendors ... Decatur was selected for the most compliant and ...
(Date:5/20/2016)... , May 20, 2016  VoiceIt is ... partnership with VoicePass. By working together, ... experience.  Because VoiceIt and VoicePass take slightly different ... engines increases both security and usability. ... excitement about this new partnership. "This ...
(Date:4/28/2016)... , April 28, 2016 Infosys ... (NYSE: INFY ), and Samsung SDS, a global ... that will provide end customers with a more secure, fast ...      (Logo: ) , ... but it also plays a fundamental part in enabling and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
(Date:6/23/2016)... 23, 2016 Andrew ... Published recently in ... journal from touchONCOLOGY, Andrew D Zelenetz , ... cancer care is placing an increasing burden on ... biologic therapies. With the patents on many biologics ...
(Date:6/23/2016)... San Francisco, CA (PRWEB) , ... June 23, ... ... capture (EDC) software, is exhibiting at the Pennsylvania Convention Center and will showcase ... DIA Annual conference. ClinCapture will also be presenting a scientific poster on Disrupting ...
(Date:6/23/2016)... Connecticut (PRWEB) , ... June 23, 2016 , ... ... introduce a new line of intelligent tools designed, tuned and optimized exclusively for ... September 12–17 in Chicago. The result of a collaboration among several companies with ...
Breaking Biology Technology: