Navigation Links
Bird flu mutation study offers vaccine clue
Date:4/8/2013

gglutinin enabled the protein to tolerate higher levels of acidity. Viruses with these mutations and others that enabled them to bind to different receptors were able to replicate more efficiently in ferrets and spread from one animal to another.

The results have important implications for designing vaccines against potential pandemic strains of bird flu. Live attenuated flu vaccines (LAIV) might be used in a pandemic situation because it is possible to manufacture many more doses of this type of vaccine than of the killed virus vaccines used to protect against seasonal flu. LAIV are based on weakened viruses that don't cause illness, but they still have to replicate in order to elicit a strong immune response. Viruses with modified haemagglutinin proteins induced strong antibody responses in ferrets in this study, suggesting that vaccines with similar modifications might prove more effective than those tested previously.

"We can't predict how bird flu viruses will evolve in the wild, but the more we understand about the kinds of mutations that will enable them to transmit between humans, the better we can prepare for a possible pandemic," said Professor Barclay.

The research was funded by the Medical Research Council and the Wellcome Trust and published in the Journal of General Virology.


'/>"/>

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London
Source:Eurekalert

Page: 1 2

Related biology news :

1. One gene, many mutations
2. Found a genetic mutation causing mental retardation very similar to Angelman syndrome in Amish
3. Sleator lab identifies single point mutation in Listeria monocytogenes
4. Why a hereditary anemia is caused by genetic mutation in mechanically sensitive ion channel
5. Mutation altering stability of surface molecule in acid enables H5N1 infection of mammals
6. Research discovers gene mutation causing rare eye disease
7. Animal model of human evolution indicates thick hair mutation emerged 30,000 years ago
8. Consumers have few negative reactions to the results of genetic testing for cancer mutations
9. Mitochondrial mutations: When the cells 2 genomes collide
10. Researchers discover mutations linked to relapse of childhood leukemia
11. Gene mutation immortalizes malignant melanoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... Is cancer an inevitable consequence of aging? , Although ... consequence of aging, the risk of developing several common ... puzzled by the apparent decrease with age in the ... possible solution to this puzzle was presented in a ... by Professor James P. Brody of the Department ...
(Date:7/13/2014)... COLUMBUS, Ohio A new study in women suggests ... before eating a single high-fat meal can slow the ... questioned study participants about the previous day,s stressors before ... 60 grams of fat. The scientists then measured their ... to burn calories and fat and took measures ...
(Date:7/11/2014)... fires burning in eastern New South Wales, Australia when ... At 03:35 UTC on July 11 (12:35 p.m. local ... over eastern New South Wales (NSW), the Moderate Resolution ... of the region and spotted smoke (light brown) from ... bands, are outlined in red. , The New South ...
Breaking Biology News(10 mins):Weighty issue: Stress and high-fat meals combine to slow metabolism in women 2Weighty issue: Stress and high-fat meals combine to slow metabolism in women 3Weighty issue: Stress and high-fat meals combine to slow metabolism in women 4
... June 5, 2012 /PRNewswire-iReach/ -- Global Information ... discounted registration for three important international healthcare and biotechnology ... Antibody Engineering Summit 2012 November 6 ... Annual Protein & Antibody Engineering Summit (PEGS Europe) presents ...
... Ph.D., Wellcome Trust Principal Research Fellow and Head, ... of Emmanuel College, Cambridge, has been bestowed the ... recognizing exemplary leadership in the international microbiological community. ... of Virginia, says Smith is "internationally recognized as ...
... (June 6, 2012) Two studies appearing in the ... freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ , evaluate the ... pancreatic tissues, in addition to a clinical study that ... islets are better than cultured islets , A ...
Cached Biology News:Early Bird Offers on Healthcare and Biotechnology Conferences, Save Up To 20% by Registering with Global Information 2Early Bird Offers on Healthcare and Biotechnology Conferences, Save Up To 20% by Registering with Global Information 3The American Society for Microbiology honors Geoffrey L. Smith 2Some factors that impact islet transplantation explored in Cell Transplantation papers 2Some factors that impact islet transplantation explored in Cell Transplantation papers 3Some factors that impact islet transplantation explored in Cell Transplantation papers 4
(Date:7/11/2014)... 2014 , Not for release, publication ... from any jurisdiction where to do so would constitute a ... Shire plc ("Shire" or the "Company") (LSE: SHP, NASDAQ: ... confirms it has held a meeting with representatives of AbbVie. ... the prior agreement or approval of AbbVie. A ...
(Date:7/11/2014)...  Researchers have pioneered a revolutionary new way ... called Virtual Finger, allows scientists to move through ... synapses using the flat surface of their computer ... studies orders of magnitude more efficient, saving time, ... many areas of experimental biology. The software and ...
(Date:7/10/2014)... 10, 2014 Understanding the need for ... lines, and the gap that currently exists in this ... its industry-leading portfolio of validated ion channel and GPCR ... cell lines, as ion channels control many critical physiological ... activity creates the potential to treat a variety of ...
(Date:7/10/2014)... July 10, 2014 EvoDerma ’s NOOME ... This rejuvenating device now comes with a second treatment cup ... time. , The new cup is thinner on the edges ... to target rough, thin and uneven surfaces on the face, ... for a stimulating treatment on areas such as the cheeks ...
Breaking Biology Technology:Shire plc - Statement re: Media Speculation 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2
... BioPharma Have Entered into an Agreement Under, Which Genmab Will ... ... USA, COPENHAGEN, Denmark and REDWOOD CITY, California, February 21, ... ) announced today that they have entered into an agreement,under ...
... a,global provider of products and services that improve the ... by the New York,Department of Health for its public ... to maintain emergency response readiness, New,York has purchased more ... two years., Cardinal Health has already shipped 850 ...
... (OTC,Bulletin Board: SNKTY), a Life Sciences company engaged ... of healthy aging, today announced,that Dr. Mark Nestor ... Symposium in Miami., In his presentation to ... attributes of Pyratine-6(TM) for the treatment of,photodamaged skin ...
Cached Biology Technology:Genmab and PDL BioPharma Sign Purchase Agreement for Antibody Manufacturing Facility 2Genmab and PDL BioPharma Sign Purchase Agreement for Antibody Manufacturing Facility 3Genmab and PDL BioPharma Sign Purchase Agreement for Antibody Manufacturing Facility 4Genmab and PDL BioPharma Sign Purchase Agreement for Antibody Manufacturing Facility 5New York Strengthens Emergency Preparedness with Cardinal Health Ventilators 2Dr. Mark Nestor Presents on Pyratine-6(TM) at the South Beach Symposium 2Dr. Mark Nestor Presents on Pyratine-6(TM) at the South Beach Symposium 3
... Detection System combines the indirect labeling ... and Signets unique formulation of ultra ... reliablility. Signet reagents will achieve excellent ... automated protocols. ,Signets USA Detection ...
6X Loading Buffer is intended for gel electrophoresis of DNA fragments or PCR products....
6X DNA Gel Loading Buffer is intended for gel electrophoresis of DNA fragments or PCR products....
Makes gels easy to load and track during electrophoresis. 10X concentrate of Bromophenol Blue, Xylene Cyanol, glycerol solution in TE...
Biology Products: