Navigation Links
Bird flu in live poultry markets are the source of viruses causing human infections
Date:5/13/2013

On 31 March 2013, the Chinese National Health and Family Planning Commission announced human cases of novel H7N9 influenza virus infections. A group of scientists, led by Professor Chen Hualan of the Harbin Veterinary Research Institute at the Chinese Academy of Agricultural Sciences, has investigated the origins of this novel H7N9 influenza virus and published their results in Springer's open access journal Chinese Science Bulletin (SpringerOpen).

Following analysis of H7N9 influenza viruses collected from live poultry markets, it was found that these viruses circulating among birds were responsible for human infections. These results provide a basis for the government to take actions for controlling this public health threat. The novel H7N9 influenza virus was identified in China as the agent, that causes a flu-like disease in humans, resulting in some deaths.

A total of 970 samples were collected from live poultry markets and poultry farms located in Shanghai and Anhui Province. Samples analyzed included drinking water, feces, contaminated soil, and cloacal and tracheal swabs. Of these samples, 20 were positive for the presence of H7N9 influenza viruses. All of the positive samples originated from live poultry markets in Shanghai. Of these 20 positive samples, 10 were isolated from chickens, 3 from pigeons, and 7 were from environmental samples.

The complete genome of three H7N9 isolates, from a chicken, pigeon, and environmental sample, was sequenced and deposited into the GISAID database. Genetic analysis of these isolates revealed high homology across all eight gene segments. The analysis of these novel H7N9 influenza virus isolates showed that that the six internal genes were derived from avian H9N2 viruses, but the ancestor of their hemagglutinin (HA) and neuraminidase (NA) genes is unknown.

HA receptor-binding specificity is a major molecular determinant for the host range of influenza viruses. Within the HA protein of novel H7N9 viruses, there was a leucine residue at position 226, which is characteristic of the HA gene in human influenza viruses. This finding implies that H7N9 viruses have partially acquired human receptor-binding specificity.

The authors conclude: "We suggest that strong measures, such as continued surveillance of avian and human hosts, control of animal movement, shutdown of live poultry markets, and culling of poultry in affected areas, should be taken during this initial stage of virus prevalence to prevent a possible pandemic. Additionally, it is also imperative to evaluate the pathogenicity and transmissibility of these H7N9 viruses, and to develop effective vaccines and antiviral drugs so as to reduce their adverse effects upon human health."


'/>"/>

Contact: Renate Bayaz
renate.bayaz@springer.com
49-622-148-78531
Springer
Source:Eurekalert

Related biology news :

1. £12 million funding to tackle devastating livestock and poultry viruses
2. Promoting poultry health through diet
3. Appetite genes are key to better diets for poultry, study shows
4. New Market Forecasts Available for Critical Global Biotechnology Testing and Screening Markets: Molecular Diagnostics, Hematology, Clinical Chemistry and Nucleic Acid Testing
5. Markets for PCR, DNA Microarray, DNA Sequencing, Mass Spectrometry and Flow Cytometry to Exceed $50 billion by 2015
6. Aldi Süd supermarkets -- energy-optimized
7. Government Emerges As the Biggest Spender on Biometrics in the SEA and ANZ Markets, Finds Frost & Sullivan
8. Molecular Imaging Agents: Targets, Technology, Markets, and Commercial Opportunities
9. Research and Markets Announces the Release of Multi-Factor Authentication Market - by Model/Type [Two, Three, Four & Five-Factor], Application & Geography - Forecasts (2012 - 2017)
10. Current water resources in Europe and Africa
11. Keck award enables Carnegie Mellon and Stanford to dramatically expand crowdsourced RNA design
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... PUNE, India , March 23, 2017 The report ... Equipment, Touchless Biometric), Industry, and Geography - Global Forecast to 2022", published by ... growing at a CAGR of 29.63% between 2017 and 2022. ... ... Logo ...
(Date:3/22/2017)... YORK , March 21, 2017 ... Marketing Cloud used by retailers such as 1-800-Flowers ... its platform — Product Recommendations and Replenishment. Using Optimove,s ... give more personalized product and replenishment recommendations to ... but also on predictions of customer intent drawn ...
(Date:3/20/2017)... March 20, 2017 PMD Healthcare announces the ... and Wellness Management System (WMS), a remote, real-time lung ... 2010, PMD Healthcare is a Medical Device, Digital Health, ... dedicated to creating innovative solutions that empower people to ... intent focus, PMD developed the first ever personal spirometer, ...
Breaking Biology News(10 mins):
(Date:4/21/2017)... , ... April 21, 2017 , ... ... dedicated to nourishing a range of emerging bio and technology start-ups, is hosting ... 21, 2017. This double event will start with libations and networking at 3:30 ...
(Date:4/20/2017)... (PRWEB) , ... April 20, 2017 , ... USDM ... for the life sciences and healthcare industries, is pleased to announce Holger Braemer ... established USDM subsidiary “USDM Europe GmbH” based in Germany. , Braemer is an ...
(Date:4/20/2017)... ... April 20, 2017 , ... Parallel6™ , the leader in mClinical™ technologies ... they were named one of the 2017 Top 10 eClinical Trial Management Solution ... pharmaceutical industry. , “We take pride in honoring Parallel6 as one of the top ...
(Date:4/19/2017)... ... , ... The Vibrating Orifice Aerosol Generator (VOAG) was developed ... of known diameters for research applications such as for calibrating droplet measuring instruments, ... droplets. , The VOAG requires forcing liquid out of an orifice about ...
Breaking Biology Technology: