Navigation Links
Biotherapeutic Innovations on Display at AAPS National Biotechnology Conference
Date:5/11/2010

ARLINGTON, VA (May 11, 2010) Advancement in the treatment of cocaine overdoses and a new defense in the fight against HIV are just two examples of the groundbreaking research that will be unveiled at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference (NBC). The conference takes place Sunday, May 16 -Thursday, May 20 at the Hilton San Francisco Union Square in San Francisco, Calif.

A Possible Treatment for Cocaine Addiction

Researchers from the University of Kentucky have discovered high-activity mutants of human butyrylcholinesterase (BChE) that have potential value in the development of anti-cocaine medication. The ideal treatment accelerates cocaine metabolism by producing biologically inactive metabolites via a route similar to the primary cocaine-metabolizing pathway.

"Cocaine addiction and overdose are well-known public health problems; there is no FDA (Food and Drug Administration)-approved medication specifically for cocaine abuse treatment," said Chang-Guo Zhan, Ph.D., research team leader and professor of pharmaceutical sciences at Kentucky. "In this research, we aim to design and discover an efficient cocaine hydrolase, which can be used for therapeutic treatment of cocaine overdose, and we have discovered one by engineering BChE."

The design has been successfully tested in mice. Zhan will present this research during the Sunrise Session on "Computational Approaches to Protein Drug Discovery and Development," from 7 a.m. to 8 a.m. on Tuesday, May 18, and at the Roundtable Session on "Rational Design of Protein Drug Stabilization," from 10:30 a.m. to 12:00 p.m. on Wednesday, May 19.

Developing Countries See Hope in the Battle against HIV

The possibility for a microbiocide-based HIV prevention measure holds particular promise for developing countries, particularly in sub-Saharan Africa, where the number of people living with HIV, as of 2008, was 22.4 million according to a report by the Joint United Nations Programme on HIV/AIDS and the World Health Organization . Microbiocides gives women, particularly in patriarchal societies, a level of confidence and control when it comes to contraception use; this particular microbiocide would be a dissolving film as opposed to microbiocides that require a plastic applicator, which makes for more discreet usage and less waste.

These studies and other novel research will be presented during a week of educational programming devoted to advancing health through biotherapeutics. Conference programming consists of a Plenary Session, symposia, roundtables, posters, hot topics, and concludes with two short courses. Additionally, the Exposition Hall will be hosting over 100 companies.


'/>"/>

Contact: Joseph Catapano
catapanoj@aaps.org
703-248-4772
American Association of Pharmaceutical Scientists
Source:Eurekalert

Related biology news :

1. Leaders from the National Academies gather to discuss engineering innovations in health care
2. MIT student develops new innovations to selectively kill cancer cells
3. New research program for energy innovations
4. Innovations in Pediatric Medicine International Conference brings together pediatrics experts
5. Innovations in Pediatric Medicine CME conference brings together national pediatrics experts
6. Improving industry efficiency through environmental innovations
7. New chemical radar among national security innovations in ACS podcast
8. Sonic Innovations Celebrates 10-Year Anniversary
9. Synaptics SecurePad(TM) Selected as CES Innovations 2008 Design and Engineering Award Honoree
10. OHSU turns innovations into commercial opportunities at record pace
11. Touch the Earth to display at Earth Day on National Mall
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... , April 28, 2016 First quarter ... (139.9), up 966% compared with the first quarter of 2015 ... totaled SEK 589.1 M (loss: 18.8) and the operating margin was ... (loss: 0.32) Cash flow from operations was SEK 249.9 ... 2016 revenue guidance is unchanged, SEK 7,000-8,500 M. The ...
(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
(Date:3/29/2016)... LegacyXChange, Inc. (OTC: LEGX ... Protect are pleased to announce our successful effort to ... of writing instruments, ensuring athletes signatures against counterfeiting and ... athletes on LegacyXChange will be assured of ongoing proof ... Bill Bollander , CEO states, "By inserting ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... Cancer ... what they believe could be a new and helpful biomarker for malignant pleural ... Click here to read it now. , Biomarkers are components in the ...
(Date:6/27/2016)... NC (PRWEB) , ... June 27, 2016 , ... ... mission to bring innovative medical technologies, services and solutions to the healthcare market. ... and implementation of various distribution, manufacturing, sales and marketing strategies that are necessary ...
(Date:6/27/2016)... PHILADELPHIA , June 27, 2016  Liquid ... today announced the funding of a Sponsored Research ... study circulating tumor cells (CTCs) from cancer patients.  ... changes in CTC levels correlate with clinical outcomes ... therapies. These data will then be employed to ...
(Date:6/24/2016)... -- Regular discussions on a range of subjects including policies, debt ... said Poloz. Speaking at a lecture to the ... pointed to the country,s inflation target, which is set by ... "In certain areas there needs to ... goals, why not sit down and address strategy together?" ...
Breaking Biology Technology: