Navigation Links
Biosensors reveal how single bacterium gets the message to split into a swimming and a stay-put cell
Date:6/3/2010

Some species of bacteria perform an amazing reproductive feat. When the single-celled organism splits in two, the daughter cell - the swarmer - inherits a propeller to swim freely. The mother cell builds a stalk to cling to surfaces.

University of Washington (UW) researchers and their colleague at Stanford University designed biosensors to observe how a bacterium gets the message to divide into these two functionally and structurally different cells. The biosensors can measure biochemical fluctuations inside a single bacteria cell, which is smaller than an animal or plant cell.

During cell division, a signaling chemical, found only in bacteria, helps determine the fate of the resulting two cells. The signal is a tiny circular molecule called cyclic diguanosine monophosphate or c-di-GMP.

By acting as an inside messenger responding to information about the environment outside the bacteria cell, c-di-GMP is implicated in several bacterial survival strategies. In harmless bacteria, some of these tactics keep them alive through harsh conditions. In disease-causing bacteria, c-di-GMP is thought to regulate antibiotic resistance, adhesiveness, biofilm formation, and cell motility.

In their study, the UW-led team of scientists looked at cell division in a species of disease bacteria that fends off treatment and establishes a stronghold by using these defenses, Pseudomonas aeruginosa. This is the rod-shaped pathogen that causes life-shortening, chronic lung infections in people with cystic fibrosis, burns, and suppressed immune systems associated with cancer. The researchers also examined cell-division in a harmless lake and stream dwelling bacteria, Caulobacter crescentus.

The researchers' findings will be published in the June 4 Science. The senior author is Dr. Samuel Miller, UW professor of medicine, microbiology, immunology, and genome science. Miller directs the Northwest Regional Center of Excellence for Bi
'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. UCLA researchers show how worlds smallest coffee ring may help biosensors detect disease
2. New biosensors reveal workings of anti-psychotic drugs in the living brain
3. Photonic crystal biosensors detect protein-DNA interactions
4. Animal study reveals new target for antidepressants
5. Powerful genome barcoding system reveals large-scale variation in human DNA
6. Revealing the ancient Chinese secret of sticky rice mortar
7. Queens researchers reveal parasitic threat to animals and the environment
8. New study reveals ways to better inhibit blood clots
9. New study reveals link between climate footprints and mass mammal
10. New research reveals Hurricane Katrinas impact on ecological and human health
11. Odd mosaic of dental features reveals undocumented primate
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biosensors reveal how single bacterium gets the message to split into a swimming and a stay-put cell
(Date:9/30/2014)... Munich report that a new class of chemical ... drugs. They have also pinpointed the relevant target ... agents. , Researchers led by LMU,s Professor ... Technische Universitt Mnchen have identified a class of ... the fight against malignant tumors. The compound is ...
(Date:9/30/2014)... 2014  Spectra Automation, a trusted supplier ... and power generation industries, announced today the ... an easy-to-use and cost-effective data collection, analysis ... laboratories. Most upstream process ... systems. Accessing and consolidating data from these ...
(Date:9/29/2014)... Clostridium ramosum , coupled with a high-fat diet, may ... week in mBio , the online open-access journal of ... from the German Institute of Human Nutrition Potsdam-Rehbruecke in Nuthetal ... ramosum gained weight when fed a high-fat diet. Mice ... obese even when consuming a high-fat diet, and mice that ...
Breaking Biology News(10 mins):Cancer therapy: Driving cancer cells to suicide 2Spectra Automation Introduces RECONN Bioprocess Manager 2Gut bacteria promote obesity in mice 2
... press release is available in German . (Jena) ... Armstrong and Buzz Aldrin created arguably the most famous footprints ever. ... onto the surface of our satellite their footprints remain almost unchanged. ... blow them away they will be visible forever. Not quite ...
... February 7, 2013 The Vilcek Foundation is pleased to ... of the 2013 Vilcek Prize for Biomedical Science. Drs. Flavell ... and investigators with the Howard Hughes Medical Institute, were selected ... innate immune system. "We are pleased to ...
... Medical Center scientists have synthesized a peptide that shows ... neurodegenerative disorders, and cancer through an ability to induce ... fundamental recycling process in which intracellular enzymes digest unneeded ... building blocks, which are then reassembled into new parts. ...
Cached Biology News:Waste dump at the end of the world 2Waste dump at the end of the world 3Vilcek Prize for Biomedical Science split between 2 giants of immunology 2Vilcek Prize for Biomedical Science split between 2 giants of immunology 3Vilcek Prize for Biomedical Science split between 2 giants of immunology 4Unique peptide could treat cancers, neurological disorders, and infectious diseases 2
(Date:10/1/2014)... 2014 METTLER TOLEDO’s newly improved XS ... balances as well as a dual range ... the new SmartPan™ weighing pan delivers results up to ... all balances, ergonomic design details mean users no longer ... for long periods in front of the balance. Barbara ...
(Date:10/1/2014)... 2014 Pfanstiehl has announced the launch ... in the USA under ... recognized for playing a key role in protein ... evidence that media supplementation with mannose can improve ... according to Dr. Christopher Wilcox , VP, ...
(Date:10/1/2014)... 30, 2014 New applications of structures ... have evolved in nature over millennia are featured in ... for applications in biophotonics in the October issue ... journal is published by SPIE, the international society for ... of the peer-reviewed articles are accessible via open access. ...
(Date:10/1/2014)... 2014 This report analyzes the ... Million by the following Product Segments: Proteases, ... end-use segments also analyzed are Pharmaceuticals & ... report provides separate comprehensive analytics for the ... and Latin America. Annual estimates and forecasts ...
Breaking Biology Technology:METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 2METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 3Pfanstiehl Launches cGMP-produced Mannose for Cell Culture Media Optimization & Glycoprotein Biosynthesis 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 2Biomimetic and bioinspired materials enable new healthcare options, reports Journal of Biomedical Optics 3Global Specialty Enzymes Industry 2Global Specialty Enzymes Industry 3Global Specialty Enzymes Industry 4Global Specialty Enzymes Industry 5Global Specialty Enzymes Industry 6Global Specialty Enzymes Industry 7Global Specialty Enzymes Industry 8Global Specialty Enzymes Industry 9Global Specialty Enzymes Industry 10Global Specialty Enzymes Industry 11Global Specialty Enzymes Industry 12Global Specialty Enzymes Industry 13Global Specialty Enzymes Industry 14Global Specialty Enzymes Industry 15Global Specialty Enzymes Industry 16Global Specialty Enzymes Industry 17Global Specialty Enzymes Industry 18Global Specialty Enzymes Industry 19Global Specialty Enzymes Industry 20Global Specialty Enzymes Industry 21Global Specialty Enzymes Industry 22Global Specialty Enzymes Industry 23Global Specialty Enzymes Industry 24Global Specialty Enzymes Industry 25Global Specialty Enzymes Industry 26
... , MORRISVILLE, N.C. , April 23 Asymchem Laboratories ... as Director of Formulation Development, Dr. Pingzhong Huang as Director of Chemical ... Development. , , , ... (George) Xu joined Asymchem on February 1, 2010 .  He ...
... ... Awards Program recognizes these organizations for their outstanding innovations and excellence in the use ... research, and clinical trials. , ... Needham, Mass. (PRWEB) April 23, 2010 -- Bio-IT World magazine announced ...
... ... ISSSEEM conference will be of interest only to those who are going to ... live a life of happiness and value.” The International Society for ... annual conference, Evidence-based Spirituality for the 21st Century, June 25-29, 2010 at the ...
Cached Biology Technology:Asymchem Laboratories Hires Three New Employees: Guojie Xu, Pingzhong Huang, and Xiaojun Huang 2BIO-IT World Announces the Winners of its 2010 Best Practices Awards Program 2BIO-IT World Announces the Winners of its 2010 Best Practices Awards Program 3BIO-IT World Announces the Winners of its 2010 Best Practices Awards Program 4BIO-IT World Announces the Winners of its 2010 Best Practices Awards Program 5BIO-IT World Announces the Winners of its 2010 Best Practices Awards Program 620th Annual ISSSEEM Conference – Evidence-based Spirituality for the 21st Century 220th Annual ISSSEEM Conference – Evidence-based Spirituality for the 21st Century 3
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Request Info...
Biology Products: