Biosensor for measuring stress in cells(ues measures the slightest changes in th...)

Date:5/16/2008

ues measures the slightest changes in the oxidation state of glutathione without destroying the cell. Even more relevant, however, is its precise time resolution, as Tobias Dick explains: In order to measure short-term variations of oxidation state, the systems needs to react instantly and dynamically. This is guaranteed with our biosensor, which works down to the scale of seconds. The measuring system allows researchers to determine those short-term variations that occur when reactive oxygen compounds are released as signaling molecules. However, the biosensor is equally suitable for use in pharmaceutical research, for example, to determine the effect of new substances or plant food constituents on oxidative processes and, thus, on the stress status of cells.

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Contact: Dr. Sibylle Kohlstdt s.kohlstaedt@dkfz.de Helmholtz Association of German Research Centres Source:Eurekalert

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