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Biophysical Society announces New and Notable Symposium speakers
Date:1/17/2012

Rockville, MD The Biophysical Society has announced the speakers for the New and Notable Symposium at the Society's 56th Annual Meeting in San Diego, California. The New and Notable Symposium highlights the latest and most exciting discoveries in biophysics. Speakers are nominated by the Society's membership and selected by the Program Committee. Over 250 nominations were received this year. The session will take place on Sunday, February 26, 2012, 10:45 AM to 12:45 PM in Ballroom 20D of the San Diego Convention Center.

In putting the session together, William Zagotta and Sharona Gordon, both of the University of Washington and Co-Chairs of the Symposium and the Program Committee, noted, "We are excited by the diverse new work that will be presented at this year's New and Notable Symposium. From single-molecule studies through male fertility, the seven presentations will show off the breadth of fields represented by the Biophysical Society and the rigor of the biophysical approach. We are particularly proud to feature a number of junior investigators."

New and Notable Symposium Speakers and Information:

SINGLE-BASE PAIR UNWINDING AND ASYNCHRONOUS RNA RELEASE BY THE HEPATITIS C VIRUS NS3 HELICASE

Wei Cheng, University of Michigan

Nonhexameric helicases use adenosine triphosphate (ATP) to unzip base pairs in double-stranded nucleic acids (dsNAs). Studies have suggested that these helicases unzip dsNAs in singlebase pair increments, consuming one ATP molecule per base pair, but direct evidence for this mechanism is lacking. Dr. Cheng and his colleagues used optical tweezers to follow the unwinding of double-stranded RNA by the hepatitis C virus NS3 helicase. Singlebase pair steps by NS3 were observed, along with nascent nucleotide release that was asynchronous with base pair opening. Asynchronous release of nascent nucleotides rationalizes various observations of its dsNA unwinding and may be used to coordinate the
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Contact: Erica Retrosi
eretrosi@biophysics.org
240-290-5600
Biophysical Society
Source:Eurekalert

Page: 1 2 3 4 5

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