Navigation Links
Biomimetic patch to be tested on tricky tendon-to-bone repairs

Two Washington University in St. Louis scientists are imitating nature as they attempt to solve one of the most difficult problems in orthopedic surgery: reattaching tendon to bone.

Their goal is to improve the success rate of rotator cuff repairs. The rotator cuff is the group of four tendons and muscles that surround the shoulder joint. When it is injured, the tendons tear or detach from the bone.

Commonly thought of as a sports injury or perhaps the scourge of orchestra conductors rotator cuff tears actually become more common with age. The highest incidence is in patients older than 60, the scientists say.

For the doctor or surgeon, the big challenge of these injuries is the limited ability of the tendon to repair itself or to reattach to the bone. Reported failure rates for rotator cuff surgeries range from 20 percent to 94 percent.

Younan Xia, PhD, the James M. McKelvey Professor in the School of Engineering & Applied Science, and Stavros Thomopoulos, PhD, associate professor of orthopaedic surgery in the School of Medicine, demonstrated an innovative solution to this problem several years ago, publishing their results in Nano Letters in 2009.

Together with co-principal investigator Leesa M. Galatz, associate professor of orthopaedic surgery in the School of Medicine, the research group has just received more than $2 million from the National Institutes of Health to take the next step toward clinical use of the biomimetic patch.

Over the next few years, they will be testing its success in repairing cuff tears in a small animal model, the rat.

The most flexible of joints

Like your hip, your shoulder is a ball and socket joint. But the head of your femur sits deep in its socket in the pelvis, so your hip joint is stable and hard to dislocate.

Not so your shoulder. The ball at the end of the humerus sits in a shallow indentation in the scapula like a golf ball sitting on

Contact: Diana Lutz
Washington University in St. Louis

Page: 1 2 3 4

Related biology news :

1. NSF funds innovative approach to biomimetic nanofiber bone regeneration
2. Fly eye paves the way for manufacturing biomimetic surfaces
3. Oceanic garbage patch not nearly as big as portrayed in media
4. NIH awards $10 million to advance microneedle patch for flu vaccination
5. Stem cell patch may result in improved function following heart attack
6. New pump created for microneedle drug-delivery patch
7. Ocean stirring and plankton patchiness
8. Even small patches of urban woods are valuable for migrating birds
9. Ancient artifacts reveals as northern ice patches melt
10. Penn team uses self-assembly to make molecule-sized particles with patches of charge
11. Isolated forest patches lose species, diversity
Post Your Comments:
Related Image:
Biomimetic patch to be tested on tricky tendon-to-bone repairs
(Date:7/23/2014)... Honey bees, especially the young, are highly sensitive to ... to maintain temperatures within a narrow range. Recently published ... Tufts University,s School of Arts and Sciences, is the ... within a hive in process similar to how humans ... and skin. , "This study shows how workers ...
(Date:7/23/2014)... Popeye super strength, but it also holds the promise ... the ability to convert sunlight into a clean, efficient ... an international group using spinach to study the proteins ... the sun,s energy into carbohydrates used to power cellular ... the most efficient system ever built, capable of converting ...
(Date:7/23/2014)... the world have no access to clean drinking water. ... people die from water-related diseases every year. ETH student ... contribution to solving this problem. Working with researchers from ... Functional Materials Laboratory, the 23-year-old spent a year researching ... makes our DrinkPure filter unique is that you can ...
Breaking Biology News(10 mins):How honey bees stay cool 2Spinach could lead to alternative energy more powerful than Popeye 2ETH student develops filter for clean water around the world 2
... at the Commerce Department,s National Institute of Standards ... on a process for manufacturing integrated circuits at ... used it to develop a method for engineering ... three-dimensional surfaces. As described in a ...
... 2009] Researchers at the Swedish medical university Karolinska Institutet (KI) ... and parietal parts, to increase the understanding of the capacity ... neurons in the brain interact. One of the findings they ... the brain,s neuronal network that restricts the number of items ...
... help people who are not responding to Anti-Retroviral Therapy, ... of Immunology . Scientists looking at monkeys with the ... virus levels in the blood to undetectable levels, by ... Anti-Retroviral Therapy (ART). Simian Immunodeficiency Virus (SIV) is ...
Cached Biology News:NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces 2NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces 3NIST-Cornell team builds world's first nanofluidic device with complex 3-D surfaces 4Computer simulations explain the limitations of working memory 2Potential new HIV drug may help patients not responding to treatment 2Potential new HIV drug may help patients not responding to treatment 3
(Date:7/22/2014)... N.J. , July 22, 2014 The Board ... BDX ) has declared a quarterly dividend of 54.5 ... holders of record on September 9, 2014. The indicated annual ... About BD BD is a leading medical technology company ... the world,s most pressing and evolving health needs. Our innovative ...
(Date:7/22/2014)... the National Institute of Standards and Technology (NIST) ... a new design for an atomic clock that ... a microcomb. , The microcomb clock, featured on ... new journal Optica ,* is the first ... its accurate conversion of optical frequencies to lower ...
(Date:7/22/2014)... engineering at the University of Texas at Dallas, has ... Texas section of the American Society of Mechanical Engineers ... 158 countries who develop engineering standards and training. They ... the world. , ASME recognized Baughn earlier this year ... Baughn retired as an engineering fellow in 2012 after ...
(Date:7/22/2014)... New York (PRWEB) July 22, 2014 ... world. The heat produced by controlled fission chain reaction ... This steam pressure is used to drive a power- ... approximately 19% of the world’s total electricity production. Nuclear ... to several under construction, planned and proposed nuclear reactor ...
Breaking Biology Technology:'Comb on a chip' powers new NIST/Caltech atomic clock design 2UT Dallas professor receives Engineer of the Year award 2Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 2Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 3
... Diagnostic Imaging,International Corp. (OTCBB: DIIG) announced today that ... Canadian Teleradiology Services,(CTS)., CTS specializes in Teleradiology, ... X-rays. This service allows hospitals in remote areas ... per day. In,large population centers, CTS can assist ...
... to Commence, LA JOLLA, Calif., Nov. ... TDLP),( ) (the "Company"), a specialty ... topically,administered medications, has retained the Investor Relations ... based in New York City, to serve ...
... Exceeds Expectations, MEMPHIS, Tenn., Nov. 10 ... focused on oncology, announced today that its,third ... the company continues,to experience banner growth. "The ... consistently exceed client expectations, and we are,ahead ...
Cached Biology Technology:Diagnostic Imaging - Enters Purchase Agreement to Acquire Teleradiology Company 2Transdel Pharmaceuticals, Inc. Retains The Investor Relations Group 2Transdel Pharmaceuticals, Inc. Retains The Investor Relations Group 3ACORN CRO Continues Growth in Strong Third Quarter 2
Anti-Goat HRP-DAB Cell & Tissue Staining Kit...
Anti-Goat HRP-AEC Cell & Tissue Staining Kit...
... 3243 provides all the materials necessary for the ... CMV antigen studies analysis. Kit Components: ... No. 5122) One bottle containing 220 mL of ... Solution (5X) - (Catalog No. 5113) One bottle ...
... CultureWell cell culture systems provide ... cultured cells for staining and ... silicone gaskets preassembled with standard ... plates. The entire system is ...
Biology Products: