Navigation Links
Biomarkers for identifying infant infections
Date:10/14/2008

Infection is the leading cause of infant deaths worldwide, and particularly a common killer of weaker, pre-term infants. Current diagnostic tests can be slow and non-specific, but researchers have now identified potential biomarkers in the blood that can rapidly identify both the onset of infection and type of microbe.

The circulatory system is a major hotbed of immune system activity, so Stephen Kingsmore and colleagues analyzed plasma samples from 107 infected and non-infected premature infants to try and identify proteins that could reliably identify an infected state.

Their analysis revealed eight proteins, associated with immune responses like inflammation and blood coagulation, which were consistently over-expressed in infected neonates. In addition, the relative levels of these serum proteins could provide insight into the type of infection (for example, the inflammatory proteins IL-6 and IL-8 were 1000-fold higher in streptococcus infections compared to other types).

Kingsmore and colleagues do note that these biomarkers are not completely accurate and thus not ready for any routine use, but with additional studies using larger numbers on infants and different types of analysis (some of which are already underway), a reliable set of infection biomarkers may soon become available.


'/>"/>

Contact: Nick Zagorski
nzagorski@asbmb.org
301-634-7366
American Society for Biochemistry and Molecular Biology
Source:Eurekalert  

Page: 1

Related biology news :

1. A search for biomarkers for early detection of colorectal cancer
2. Genetic Engineering & Biotechnology News reports on cancer biomarkers
3. Biomarkers allow doctors to match therapy to patient
4. Scientists find potential protein biomarkers for growth hormone
5. Urologists identify 7 biomarkers that may help pinpoint prostate cancer recurrence
6. Oil palm research in context: Identifying the need for biodiversity assessment
7. Researchers devise means to create blood by identifying earliest stem cells
8. Monkeys use baby talk to interact with infants
9. Soy isoflavone may inhibit common gastrointestinal illness in infants
10. Breastfeeding boost IQ in infants with helpful genetic variant
11. Study suggests new way to screen infants for fetal alcohol syndrome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biomarkers for identifying infant infections
(Date:11/21/2016)... , Nov. 21, 2016   Neurotechnology ... object recognition technologies, today announced that the MegaMatcher ... cards was submitted for the NIST Minutiae ... passed all the mandatory steps of the evaluation ... is a continuing test of fingerprint templates used ...
(Date:11/15/2016)... Md. , Nov. 15, 2016  Synthetic ... company developing therapeutics focused on the gut microbiome, ... offering of 25,000,000 shares of its common stock ... common stock at a price to the public ... proceeds to Synthetic Biologics from the offering, excluding ...
(Date:6/22/2016)... , June 22, 2016  The American College of Medical ... Show Executive Magazine as one of the fastest-growing trade ... 25-27 at the Bellagio in Las Vegas ... highest percentage of growth in each of the following categories: ... companies and number of attendees. The 2015 ACMG Annual Meeting ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... , ... December 02, 2016 ... ... a consortium of pharmaceutical and biotechnology companies dedicated to collaboratively developing improved ... interested in supplying a vendor-supported, portable online UHPLC, with robust, probe-based sampling. ...
(Date:12/2/2016)... The immunohistochemistry (IHC) market is projected ... of 7.3% during the forecast period of 2016 to 2021 dominated ... accounted for the largest share of immunohistochemistry (IHC) market, by end ... , , ... market spread across 225 pages, profiling 10 companies and supported with ...
(Date:11/30/2016)... today announced the appointment of Joshua F. Coleman , ... Dr. Coleman will oversee clinical content development and curation of ... software suite empowers molecular pathologists with a seamless workflow for ... from quality control through reporting. ... , , ...
(Date:11/30/2016)... RATON, Fla. , Nov. 30, 2016 ... biotherapeutic products, is pleased to announce the addition of ... Avenue Kearney, Nebraska . The 15,200 ... business on November 29th, 2016 and brings the total ... Ileana Carlisle , BPC,s Chief Executive ...
Breaking Biology Technology: