Navigation Links
Biomarker MIA shows presence of neurofibromas
Date:7/3/2011

Neurofibromatosis (NF1) is a genetic condition which affects one in every 3,000 people. The severity of symptoms can range from benign 'caf au lait' patches on the skin, through small tumors under the skin and deep plexiform neurofibromas, to malignant tumors of the nerve sheath. New research published in BioMed Central's open access journal BMC Medicine shows that a simple blood test for the protein melanoma-inhibitory activity (MIA) could be used to indicate the presence of neurofibromas even if they cannot be seen.

When researchers compared the levels of MIA from blood of patients with NF1 and unaffected controls they discovered that the patients with NF1 had much higher serum levels of MIA and that the level of MIA depended on the number and size of neurofibromas and plexiform neurofibromas the patient had. Tumor biopsies also showed an increase in MIA at the cellular level.

Dr Kolanczyk said, "Using the biomarker MIA to test for the presence and growth of plexiform neurofibromas would be an easier and cheaper way of monitoring clinical course of the patients and would allow the early detection of tumors so improving the treatment, management and outcome. Detection of deep plexiform neurofibroma is currently only possible using MRI scan and since these tumors can become malignant it is important to monitor their growth closely and detect signs of malignant transformation as early as possible."


'/>"/>

Contact: Dr. Hilary Glover
hilary.glover@biomedcentral.com
44-203-192-2370
BioMed Central
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers identify biomarkers of poor outcomes in preemies
2. Scientists discover powerful biomarker panel for the early detection of breast cancer
3. Motor Neurone Disease Association study identifies MND biomarker
4. New biomarker may help diagnose ectopic pregnancies
5. Reportlinker Adds Biomarkers - technologies, markets and companies
6. New biomarker for raw milk quality detection
7. Duke, LabCorp combine forces to create the Biomarker Factory
8. New biomarkers for predicting the spread of colon cancer
9. Pacific Biomarkers, Inc. Schedules Second Quarter Conference Call for Friday, February 12, 2010
10. Assessing lead time of selected ovarian cancer biomarkers
11. Pacific Biometrics, Inc. Stockholders Approve Company Name Change to Pacific Biomarkers, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... According to the new market research report, ... (Optical Prism, Pizeoelectric, Capacitive, and Adhesives), Application (Mobile Devices, ... and Geography - Global Trends & Forecasts to 2014 ... Market is projected to cross $14.35 Billion by 2020, ... to 2020. Browse more than 78 market ...
(Date:7/10/2014)... , July 7, 2014 Fingerprint Cards, ... major design win (DW). A Chinese Top 5 smartphone OEM ... start of mass production in October 2014.   ... Top 5 smartphone OEM, which has a planned date for ... target sales volume for this phone of 3 million units. ...
(Date:7/10/2014)... Fingerprint Cards, (FPC,s) new ... (DW). An Asian OEM has selected FPC1021 for a flagship ... August 2014.   FPC is proud to announce ... planned date for start of mass production in August 2014. ... 5M, for delivery in the first half of July. The ...
Breaking Biology News(10 mins):Fingerprint Sensors Market worth $14.35 Billion by 2020 2Fingerprint Sensors Market worth $14.35 Billion by 2020 3FPC Wins DW for 1021 Touch Sensor for Flagship Smartphone from Chinese Top 5 Smartphone OEM 2FPC Wins DW and Initial Ramp Order for FPC1021 Touch Sensor for Flagship Smartphone from Asian OEM 2
... from two universities in Italy and Virginia Tech in ... protein that is responsible for the production xanthurenic acid ... plays a key role in the sexual reproduction of ... Interfering with the formation of XA could be an ...
... Results from a new, five-year study show that regular use ... breast cancer by up to 71 percent and may offer ... cancers. , The study findings were released today at ... in Washington, D.C. , "We believe this is the ...
... you ever tried to do the limbo? For ants it's ... have discovered that ants are able to learn how to ... can successfully crawl under it without slowing down. Tobias Seidl ... Meeting for the Society for Experimental Biology on Tuesday 4th ...
Cached Biology News:Oxidation defense in mosquitoes benefits malaria parasite 2COX-2 inhibitors significantly reduce risk of cancer 2
(Date:7/10/2014)... 10, 2014 EvoDerma ’s NOOME Anti-Aging ... rejuvenating device now comes with a second treatment cup to ... , The new cup is thinner on the edges for ... target rough, thin and uneven surfaces on the face, neck ... a stimulating treatment on areas such as the cheeks and ...
(Date:7/10/2014)... 10, 2014 /PRNewswire-iReach/ -- Tute Genomics, the ... announced an agreement with Lineagen, Inc., to ... NextStep Dx PLUS.  Lineagen, focused on ... disorders, currently offers FirstStep Dx PLUS, ... used by healthcare providers as a first-line ...
(Date:7/10/2014)... D.C., June 17, 2014 Using microscopic polymer ... specific gases, researchers at MIT,s Quantum Photonics Laboratory ... levels in the parts-per-billion range. Optical sensors are ... their high signal-to-noise ratio, compact, lightweight nature, and ... gas sensors had been developed before, the MIT ...
(Date:7/10/2014)... geckos and spiders can sit upside down forever. Nanophysics makes ... this in an article just published in Physical Review ... , Geckos and spiders that seem to be able to ... researchers worldwide for many years. We will soon be able ... as the gecko,s foot. But the fact is, sooner or ...
Breaking Biology Technology:Introducing a New Bonus Treatment Cup for EvoDerma’s NOOME Anti-Aging Motion 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4Swell new sensors 2Even geckos can lose their grip 2
... Hayden, secretary of the Wisconsin Department of Health ... chief administrative officer for Dean Health Systems , ... use of health information technology, particularly Wisconsin's eHealth ... IT adoption. , ,His 23-year career in healthcare administration ...
... attack on multiple flanks. Google , the Internet utility and ... March 2007, according to Hitwise , is drawing out entrepreneurs ... can slay the giant. One intriguing possibility is evident in the ... talking about a merger or other sharing of capabilities, according to ...
... has announced that Berbee Information Networks , which is ... $250,000 in state Technology Zone tax credits. , ,Berbee, founded ... building and a 51,500-square-foot data center in the New Venture ... , ,The project is expected to cost $1.9 million and ...
Cached Biology Technology:DHC 2007: Hayden says technology creates magic moment for healthcare delivery 2DHC 2007: Hayden says technology creates magic moment for healthcare delivery 3DHC 2007: Hayden says technology creates magic moment for healthcare delivery 4Outflanking the Google, Yahoo, MSN juggernaut 2Outflanking the Google, Yahoo, MSN juggernaut 3Outflanking the Google, Yahoo, MSN juggernaut 4Outflanking the Google, Yahoo, MSN juggernaut 5Outflanking the Google, Yahoo, MSN juggernaut 6
... template is designed to allow kanamycin/neomycin ... It combines a prokaryotic promoter (gb2) ... E.coli with a eukaryotic promoter (PGK) ... cells. The prokaryotic promoter gb2 is ...
... The loxP-PGK-gb2-neo-loxP template is designed ... and eukaryotic cells. The loxP-PGK-gb2-neo-loxP ... which combines a prokaryotic promoter (gb2) ... E.coli with a eukaryotic promoter (PGK) ...
... This depletion cocktail is ... T cells from suspensions of ... separated using the StemSep (or ... cell selection system. The CD4+ ...
Standard Fluka For microscopy (Hist.) redox indicator...
Biology Products: