Navigation Links
Biologists use mathematics to advance our understanding of health and disease
Date:2/20/2010

les in biology, such as from interactions between sick and healthy people to the spread of global pandemics. Whereas models of this sort can inform public health decisions on a global scale, Tyson's research addresses basic science at the smallest scale bridging the gap from molecules to cells. "We have to first understand the molecular basis of normal cell behavior; then we have a chance of figuring out how the system is broken in diseased cells," said Tyson.

"What decision-making processes tell a cell when to grow and divide and when to just hang-out? It is mistakes in this decision process that cause cancer. Tumors are cells growing when and where they shouldn't. Cancer is a collection of diseases caused by faulty decision-making at the cellular level. The cells are no longer obeying the rules. We know the cause is in the molecules that are supposed to be enforcing these rules."

During the course of his research, Tyson and colleagues have used computer simulations to test their math models. "If the math model behaves in the computer the way cells behave in the lab, we gain confidence that we understand the molecular interactions correctly. If not, we can be sure that our models are missing something important."

Tyson will talk about the control of cell division in yeast and in mammalian cells. "Yeast cells are easy to work with in the lab, and their molecular control systems are very similar to the control systems in mammalian cells," he said As a result of the success that Tyson and his colleagues have had in modeling yeast cell growth and division, they are now making the transition to mammalian cells and cancer.

"We do not yet have an engineer's understanding of normal mammalian cell proliferation and of what goes wrong in cancer cells," Tyson said. "Cancer treatment is still a matter of cutting out, blasting, or poisoning cancer cellsand any normal cells that get in the way. We could be more subtle and perhaps more effec
'/>"/>

Contact: Susan Trulove
strulove@vt.edu
540-231-5646
Virginia Tech
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Biologists image birth of blood-forming stem cells in embryo
2. Penn biologists determine microRNA activity is suppressed in mouse ovum
3. CCNY biologists identify new spiny pocket mouse species
4. Penn biologists explain how organisms can tolerate mutations, yet adapt to environmental change
5. Biologists merge methods, results from different disciplines to find new meaning in old data
6. New handbook for biologists who need more competence or confidence in statistics
7. Biologists discover bacterial defense mechanism against aggressive oxygen
8. Beyond genomics, biologists and engineers decode the next frontier
9. Biologists, educators recognize excellence in evolution education
10. NIMBioS hosts tutorial on optimal control and optimization for biologists
11. Biologists discover death stench is a universal ancient warning signal
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Biologists use mathematics to advance our understanding of health and disease
(Date:7/9/2014)... Bacteria found in the bladders of healthy women ... form of incontinence, according to researchers from Loyola ... These findings, published July 9, 2014, in the ... , suggest that bacterial communities may play a ... incontinence (UUI) is a common, yet poorly understood, ...
(Date:7/9/2014)... shifts the geographic ranges in which animals can be ... their parasites. Does an increased range for a host ... Not necessarily, says a team of UC Santa Barbara ... a study published in the Journal of Biogeography ... species, the opposite may happen: Hosts may actually lose ...
(Date:7/9/2014)... nature,s ability to split the water molecule during ... artificial photosynthesis for clean, green and renewable energy ... scientists led by researchers with the Lawrence Berkeley ... Accelerator Laboratory. , Working at SLAC,s Linac ... x-ray laser, the researchers were able to take ...
Breaking Biology News(10 mins):Not at home on the range 2Not at home on the range 3Not at home on the range 4Postcards from the photosynthetic edge 2Postcards from the photosynthetic edge 3
... A study supported by the U.S. Department of Health ... findings that suggested the presence of one of several viruses ... The new study also could not find the viruses in ... not have the viruses., The HHS-supported study examined the validity ...
... 22, 2011) -- Maintaining fluid balance in the body ... the mightiest of mammals. By researching recent genomic data, ... intricate process to a turning point in evolution. ... Emeritus, University of Lausanne, along with colleagues Romain A. ...
... E.coli that plays a critical role in defending the ... have the shape of a seahorse by researchers with the ... This discovery holds far more implications for your own health ... protect you from infections by bacteria, viruses, toxins and other ...
Cached Biology News:XMRV, related viruses not confirmed in blood of healthy donors or chronic fatigue syndrome patients 2XMRV, related viruses not confirmed in blood of healthy donors or chronic fatigue syndrome patients 3XMRV, related viruses not confirmed in blood of healthy donors or chronic fatigue syndrome patients 4Fluid equilibrium in prehistoric organisms sheds light on a turning point in evolution 2Close up look at a microbial vaccination program 2Close up look at a microbial vaccination program 3Close up look at a microbial vaccination program 4
(Date:1/15/2014)... PA (PRWEB) January 15, 2014 The Pittcon ... publisher of Food Safety Tech , an e-Journal and ... signed an agreement for the second year for the co-location ... Pittcon 2014. The partnership provides that the registration fee to ...
(Date:1/15/2014)... MINNEAPOLIS , Jan. 15, 2014 ­ RedBrick ... and behavior change technology, today announces that EmblemHealth ... insurer and wellness company, is now providing the RedBrick ... digital coaching program, to all of its members. EmblemHealth ...
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains how ... latent viruses is the Epstein Barr Virus (EBV), and one ... is a chronic inflammatory disease that destroys the body’s joints. ... patients have high concentrations of EBV DNA in their bodies ...
(Date:1/15/2014)... 2014 TaiGen Biotechnology Company, Limited ("TaiGen") today announced ... a leading Russian pharmaceutical company, to develop and commercialize ... Federation , Turkey and ... a novel antibiotic for the treatment of bacterial infections ...
Breaking Biology Technology:Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4
... NEW YORK, Jan. 20, 2011 Reportlinker.com announces ... in its catalogue: Hospital General ... This is the most comprehensive ... General Radiology and radiology IT systems (PACS) in ...
... using new image and cell technologies have for the ... invading red blood cells. The researchers, from the Walter ... University of Technology, Sydney (UTS), achieved this long-held aim ... microscopy, a technology platform new to Australia. The ...
... German . Development of efficient battery systems for ... Ulm Helmholtz Institute for Electrochemical Energy Storage (HIU). Today, this ... Helmholtz Institute for Electrochemical Energy Storage in Ulm shall be ... high importance to Germany as a location of technology and ...
Cached Biology Technology:Reportlinker Adds Hospital General Radiology Census 2Malaria parasite caught red-handed invading blood cells 2Malaria parasite caught red-handed invading blood cells 3Start of the Ulm Helmholtz Institute 2Start of the Ulm Helmholtz Institute 3
... Simplify the process and you reduce ... built into the CEQ 8000. Developed using ... and leadership in capillary electrophoresis technology, the ... analysis system. This system automatically fills the ...
The external laser upgrade for the Molecular Imager FX adds a 635 nm external laser; the 555 nm long pass filter is replaced with a 605 nm band pass filter to distinguish Cy5 from 532 nm excitable dy...
... The APO-BRDU Kit is a 2-color ... total cellular DNA to detect apoptotic cells ... instructions and reagents required for measuring apoptosis ... cells for assessing reagent performance; washing, reaction ...
... The BioGenex VISION Sytem is a ... comes with proprietary digital imaging and ... digital image acquisition, analysis, archving/retrieval and ... a state-of-the-art digital imaging system that ...
Biology Products: