Navigation Links
Biological warfare in bacteria offers hope for new antibiotics
Date:7/2/2009

Scientists are to study a group of proteins that are highly effective at killing bacteria and which could hold the key to developing new types of antibiotics.

Researchers from the Universities of York and Leeds have been awarded 3.3m from the Biotechnology and Biological Sciences Research Council (BBSRC) to find out how a family of proteins known as colicins force their way into bacterial cells before destroying them.

The team, led by Professor Colin Kleanthous, from the University of York's Department of Biology, will develop earlier research that suggests colicins use decoys to mimic key parts of the cells' own protein machinery to evade their defences.

Professor Kleanthous said: "Colicins are the weapon used in the biological warfare that takes place between competing bacteria. Understanding how this group of proteins work could help scientists develop new drug delivery methods to target the bacteria that cause diseases in people."

"It's as though the colicins are carrying the equivalent of hand grenades which they can deploy without harming themselves," said Professor Sheena Radford of the University of Leeds' Faculty of Biological Sciences.

The five year programme of research aims to discover how colicins specifically penetrate Gram-negative bacteria which are protected by two membrane barriers.

It will involve collaboration between six groups of scientists from the Departments of Biology and Chemistry at the University of York and the Astbury Centre for Structural and Molecular Biology, Faculty of Biological Sciences, at the University of Leeds.


'/>"/>

Contact: James Reed
jr576@york.ac.uk
44-019-044-32029
University of York
Source:Eurekalert

Page: 1

Related biology news :

1. Keck Foundation funds study of biological interactions with nanomaterials
2. New insight into the mechanisms of voltage sensing and transduction in biological processes
3. Biological warfare: What do you need to know?
4. A mechanism to explain biological cross-talk between 24-hour body cycle and metabolism
5. Story ideas from the Journal of Biological Chemistry
6. Emerging field of neuroecology is showcased in December issue of the Biological Bulletin
7. Story ideas from the Journal of Biological Chemistry
8. Systems biologist finds novel solutions to fundamental biological problems
9. MIT applies engineering approach to studying biological pathways
10. Lensless camera uses X-rays to view nanoscale materials and biological specimens
11. Systems biology approach identifies nutrient regulation of biological clock in plants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/4/2017)... -- For the thousands of attendees at this year,s International Consumer Electronics Show ... biometric measurement devices and services, will be featuring its new line of ... Medical,s special CES Exhibit Suite , the new upper arm and ... WellnessConnected product platform.  Continue ... ...
(Date:12/22/2016)... , Dec. 20, 2016  As part of its longstanding ... leading personal genetics company, recently released its latest children,s book, ... The book focuses on the topics of inheritance and variation ... Standards (NGSS) taught in elementary school classrooms in the US. ... series by illustrator Ariana Killoran , whose previous book ...
(Date:12/20/2016)... and GENEVA, Dec, 20, 2016   Valencell ... sensor technology, and STMicroelectronics (NYSE: STM), a ... of electronics applications, announced today the launch of ... for biometric wearables that includes ST,s compact ... Valencell,s Benchmark™ biometric sensor system. Together, SensorTile ...
Breaking Biology News(10 mins):
(Date:1/17/2017)... ... January 17, 2017 , ... ... Drug Safety Technology Consortium™ (SafeTEC™), $3 million in investment towards 15+ TEC Validation ... tools and assays, and their applicability in drug safety assessment, for the industry ...
(Date:1/16/2017)... NY (PRWEB) , ... January 16, 2017 , ... ... New Jersey laws precedential publication its decision on the appeal filed by India-based ... lawsuit of breach of contract against DPCL and one of its Dishman Group’s ...
(Date:1/14/2017)... , Jan. 13, 2017  The Alliance for ... in response to FDA final guidance on ... its continued leadership in emphasizing the importance of distinct ... keenly aware of the benefits biosimilars will bring to ... Yet the portion of the Guidance dealing ...
(Date:1/13/2017)... Island, NY (PRWEB) , ... January 13, 2017 ... ... teamed up with several companies to offer its customers three new solutions for ... probe would come in handy if a customer has an oddly-shaped sample that ...
Breaking Biology Technology: