Navigation Links
Biofilms help Salmonella survive hostile conditions, Virginia Tech researchers say
Date:4/10/2013

Virginia Tech scientists have provided new evidence that biofilms bacteria that adhere to surfaces and build protective coatings are at work in the survival of the human pathogen Salmonella.

One out of every six Americans becomes ill from eating contaminated food each year, with over a million illnesses caused by Salmonella bacteria, according to the Centers for Disease Control and Prevention. Finding out what makes Salmonella resistant to antibacterial measures could help curb outbreaks.

Researchers affiliated with the Fralin Life Science Institute discovered that in addition to protecting Salmonella from heat-processing and sanitizers such as bleach, biofilms preserve the bacteria in extremely dry conditions, and again when the bacteria are subjected to normal digestive processes. The study is now online in the International Journal of Food Microbiology and will appear in the April issue.

"Biofilms are an increasing problem in food processing plants serving as a potential source of contamination," said Monica Ponder, an assistant professor of Food Science and Technology in the College of Agriculture and Life Sciences. "We have discovered that Salmonella in biofilms survive on dried foods much better than previously thought, and because of this are more likely to cause disease," Ponder said.

Outbreaks of Salmonella associated with dried foods such as nuts, cereals, spices, powdered milk and pet foods have been associated with over 900 illnesses in the last five years. These foods were previously thought to be safe because the dry nature of the product stops microbial growth.

"Most people expect to find Salmonella on raw meats but don't consider that it can survive on fruits, vegetables or dry products, which are not always cooked," Ponder said.

In moist conditions, Salmonella thrive and reproduce abundantly. If thrust into a dry environment, they cease to reproduce, but turn on genes which produce a biofilm, protecting them from the detrimental environment.

Researchers tested the resilience of the Salmonella biofilm by drying it and storing it in dry milk powder for up to 30 days. At various points it was tested in a simulated gastrointestinal system. Salmonella survived this long- term storage in large numbers but the biofilm Salmonella were more resilient than the free-floating cells treated to the same conditions.

The bacteria's stress response to the dry conditions also made it more likely to cause disease. Biofilms allowed the Salmonella to survive the harsh, acidic environment of the stomach, increasing its chances of reaching the intestines, where infection results in the symptoms associated with food poisoning.

This research may help shape Food and Drug Administration's regulations by highlighting the need for better sanitation and new strategies to reduce biofilm formation on equipment, thus hopefully decreasing the likelihood of another outbreak.


'/>"/>

Contact: Lindsay Key
ltkey@vt.edu
540-231-6594
Virginia Tech
Source:Eurekalert

Related biology news :

1. LSUHSC scientist awarded nearly $2 million to determine role of biofilms in common fungal infection
2. Mechanisms involved in resistance to the bacteria Salmonella studied in a Ph.D. thesis
3. Assessing a new technique for ensuring fresh produce remains Salmonella-free
4. Salmonella infection, but not as we know it
5. UCSB researchers discover particularly dangerous Salmonella
6. UCSB researchers find a way to detect stealthy, hypervirulent Salmonella strains
7. UCI-led study uncovers how Salmonella avoids the bodys immune response
8. Cushion plants help other plants survive
9. Not just cars, but living organisms need antifreeze to survive
10. How do corals survive in the hottest reefs on the planet?
11. Collaring tapirs to help them survive
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... First quarter 2016:   , ... the first quarter of 2015 The gross margin was ... 18.8) and the operating margin was 40% (-13) Earnings ... flow from operations was SEK 249.9 M (21.2) , ... SEK 7,000-8,500 M. The operating margin for 2016 is ...
(Date:4/15/2016)...  A new partnership announced today will help ... in a fraction of the time it takes ... life insurance policies to consumers without requiring inconvenient ... Diagnostics, rapid testing (A1C, Cotinine and HIV) and ... weight, pulse, BMI, and activity data) available at ...
(Date:3/31/2016)... , March 31, 2016   ... ("LegacyXChange" or the "Company") LegacyXChange is excited ... of its soon to be launched online site for ... https://www.youtube.com/channel/UCyTLBzmZogV1y2D6bDkBX5g ) will also provide potential shareholders a ... DNA technology to an industry that is notorious for ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016  The Prostate Cancer Foundation (PCF) is ... treatments and faster cures for prostate cancer. Members of the Class of 2016 ... countries. Read More About the Class of 2016 PCF ... ... ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample tracking software ... State Crime Laboratory, has joined STACS DNA as a Field Application Specialist. , ... Tremblay, President and COO of STACS DNA. “In further expanding our capacity as a ...
(Date:6/23/2016)... June 23, 2016 ... 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 Published recently ... peer-reviewed journal from touchONCOLOGY, Andrew D Zelenetz ... of cancer care is placing an increasing burden ... expensive biologic therapies. With the patents on many ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... new line of intelligent tools designed, tuned and optimized exclusively for Okuma CNC ... in Chicago. The result of a collaboration among several companies with expertise in ...
Breaking Biology Technology: