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Biodegradable polymers show promise for improving treatment of acute inflammatory diseases
Date:8/20/2008

yketal. In a one-step procedure, they mixed the microparticles with the proteins and centrifuged them. That immobilized the proteins on the surface of the polyketals. Laboratory experiments conducted under physiological conditions have shown that half of the bound proteins were released within 24 hours.

Also in collaboration with Davis, the researchers are testing the ability of the protein-bound polyketals to treat heart attacks.

In the next few years, Murthy and his team of graduate students and collaborators plan to continue developing new polyketals and conducting efficacy tests in cell cultures and animal studies.

"In the past few years, we have developed methods to tailor the polyketal's properties, which have already allowed us to target many different medical conditions, but our end goal is to test these treatments in humans," noted Murthy.


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Contact: Abby Vogel
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Georgia Institute of Technology Research News
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