Navigation Links
Biochemists manipulate fruit flavor enzymes
Date:8/20/2008

neration of HPL.

AOS and HPL are part of a super family of enzymes called cytochrome P450. P450 family enzymes are found in most bacteria and all known plants and animals. Although AOS or HPL are not found in humans, there are related P450 family members that help metabolize nearly half of the pharmaceuticals currently in use. In plants, AOS and HPL break down naturally-occurring, organic peroxides into GLV and jasmonate molecules. "Each flavor has a different chemical profile," Raman said.

"A notable strength of this manuscript is the combined use of structural and evolutionary biology to draw new insights regarding enzyme function. These insights led to the striking demonstration that a single amino acid substitution converts one enzyme into another, thereby showing how a single point mutation can contribute to the evolution of different biosynthetic pathways. This begins to answer the long-standing question as to how the same starting molecule can be converted into different products by enzymes that look strikingly similar," said Rodney E. Kellems, Ph.D., professor and chairman of the Department of Biochemistry & Molecular Biology at the UT Medical School at Houston.

The study dispels the earlier view that these flavor-producing enzymes are only found in plants, Raman said. "We have discovered that they are also present in marine animals, such as sea anemone and corals. However, we do not know what they do in these organisms."


'/>"/>

Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3042
University of Texas Health Science Center at Houston
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biochemists reveal details of mysterious bacterial microcompartments
2. New chemical tool kit manipulates mitochondria, reveals insights into drug toxicity
3. Consortium develops new method to manipulate genetic material
4. Researchers find new taste in fruit flies: carbonated water
5. Sugary drinks, not fruit juice, may be linked to insulin
6. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
7. The reservoir of Marburg virus identified in a species of fruit bat
8. Chemical in red wine, fruits and vegetables stops cancer, heart disease, depending on the dose
9. Ripe fruit preferred
10. International team compares 12 fruit fly genomes
11. Genome comparison of 12 fruit fly species
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... , June 27, 2014  The American Academy ... Institute of Standards and Technology (NIST) and the ... academic research and forensic science expert members to ... is an element of the NIST,s Organization of ... among the first appointments made to the new ...
(Date:7/10/2014)... , July 2, 2014  Unisys Corporation,s (NYSE: ... , Unisys Nederland N.V., today announced that it has been ... implement and manage a new Basic Provision Biometrics solution for ... Unisys won the contract with a solution based on ... software. The term of the contract is up to seven ...
(Date:7/10/2014)... 3, 2014 Research and Markets ( ... "Global Gesture Recognition & Touch-Less Sensing (2D, ... 2020" report to their offering ... Recognition & Touch-Less Sensing Market to Grow Exponentially. ... while, but the companies were unable to leverage ...
Breaking Biology News(10 mins):Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3Unisys Delivers New Basic Provision Biometrics Solution to Dutch Custodial Institutions Service 2Unisys Delivers New Basic Provision Biometrics Solution to Dutch Custodial Institutions Service 3Global Gesture Recognition & Touch-Less Sensing (2D, 3D, Ultrasonic, IR, Capacitive) Market - Forecasts to 2020 2
... Cold Spring Harbor, N.Y. -- A key item in the ... an axis that makes a leaf,s top half distinct from ... function: it ensures that the leaf develops a flattened blade ... for light harvesting and a bottom surface containing tiny pores ...
... CA Ever since insects developed a taste for ... resources to out-compete their neighbors for light to grow, ... an international team of scientists at the Salk Institute ... y Ecolgicas Vinculadas a la Agronoma (IFEVA) has discovered ...
... PARTEQ Innovations, the technology commercialization office of Queen,s ... federal government towards the establishment of a National ... of Green Chemistry technologies. The first ... Canada will bring together Canada,s leading Green Chemistry ...
Cached Biology News:Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants 2Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants 3Understanding natural crop defenses 2Understanding natural crop defenses 3Queen's receives $9.1 million to establish National Center of Excellence in green chemistry 2Queen's receives $9.1 million to establish National Center of Excellence in green chemistry 3
(Date:7/10/2014)... July 10, 2014 /PRNewswire-iReach/ -- Tute Genomics, ... today announced an agreement with Lineagen, Inc., ... Lineagen,s NextStep Dx PLUS.  Lineagen, focused ... neurological disorders, currently offers FirstStep Dx ... service used by healthcare providers as a ...
(Date:7/10/2014)... April 15, 2014 -- According to the International ... nuclear security comes from terrorists acquiring sufficient quantities ... construct a crude nuclear explosive device. The IAEA ... trafficking have involved gram-level quantities, which can be ... According to a new study appearing this week ...
(Date:7/10/2014)... in the journal PNAS (Proceedings of the National ... day and sleep deprivation have a significant effect on ... at the best time of day to test for ... administering medicines effectively. , Researchers from the University of ... the links between sleep deprivation, body clock disruption and ...
(Date:7/10/2014)... power our laptops and electric vehicles could store more ... the help of a sponge-like silicon material. , ... traditionally used in one of the battery,s electrodes, as ... capacity of graphite. A paper describing the material,s performance ... Nature Communications . , "Silicon has long been ...
Breaking Biology Technology:Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4Sensitive detection method may help impede illicit nuclear trafficking 2Time of day crucial to accurately test for diseases, new research finds 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3
... Medco Health,Solutions, Inc. (NYSE: MHS ) Chairman ... members of his senior management team, will present an,overview ... and institutional investors during its annual Analyst Day,conference on ... of Pharmacy," is scheduled to begin at 8 a.m. ...
... Abercrombie, Pfizer R&D Head Martin,Mackay, HHS Deputy Secretary Tevi ... Agenda at FDA/CMS Summit 2007, WASHINGTON, Nov. 15 ... drug approvals. Unfortunately for the biopharma sector and,investors, it,s ... on track,to grant marketing approval to 18 or fewer ...
... Brad Thompson, President,and CEO of Oncolytics Biotech Inc. ... of the company at Toronto CFA Society on ... at the National Club, 303 Bay,Street, Toronto at ... Oncolytics is a Calgary-based biotechnology company focused on ...
Cached Biology Technology:Medco to Webcast Annual Analyst Day Conference 2So Long, Old Friend: The End of the Blockbuster Drug Era? What 2008 Holds for Bringing Drugs to Market 2So Long, Old Friend: The End of the Blockbuster Drug Era? What 2008 Holds for Bringing Drugs to Market 3Media Advisory - Oncolytics Biotech Inc. to Present at Toronto CFA Society 2
... GeneBLAzer cell-based assays utilize the membrane-permeant ... the negatively charged fluorescent beta-lactamase substrates, ... readily enter the cell, where cleavage ... them into their negatively charged forms, ...
1M stock solution (238mg/ml)...
Request Info...
Chicken polyclonal to ADI1 ( Abpromise for all tested applications). Antigen: Full length native protein (purified), corresponding to amino acids 1-179 of Human ADI1. Entrez GeneID: 55256 ...
Biology Products: