Navigation Links
Better tissue healing with disappearing hydrogels
Date:6/6/2014

from donor bone fragments, so that the tissue regeneration could be accomplished only by the stem cells.

In order to track the progress of the research, the stem cells were genetically modified to include genes that give off fluorescence signals. The bone material was then coated with the hydrogels, which contained the fluorescently labeled stem cells, and implanted into the defect of the damaged mouse bone. At that point, the researchers began monitoring the repair process with longitudinal fluorescence to determine if there would be an appreciable loss of stem cells in the in vivo samples, as compared to the static, in vitro, environments. They found that there was no measurable difference between the concentrations of stem cells in the various samples, despite the fact that the in vivo sample was part of a dynamic environmentwhich included enzymes and blood flowmaking it easier for the stem cells to migrate away from the target site. That means virtually all the stem cells stayed in place to complete their work in generating new bone tissue.

"Some types of tissue repair take more time to heal than do others," said Benoit. "What we needed was a way to control how long the hydrogels remained at the site."

Benoit and her team were able to manipulate the time it took for hydrogels to dissolve by modifying groups of atomscalled degradable groupswithin the polymer molecules. By introducing different degradable groups to the polymer chains, the researchers were able to alter how long it took for the hydrogels to degrade.

Benoit believes degradable hydrogels show promise in many research areas. For example, it may be possible to initiate tissue regeneration after heart attacks without having a patient undergo difficult, invasive surgery, but a great deal of additional research is required.


'/>"/>

Contact: Peter Iglinski
peter.iglinski@rochester.edu
585-273-4726
University of Rochester
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Toward a better drug against malaria
2. New research provides better understanding of endometriosis
3. Building a better blood vessel
4. Engineering a better way to rebuild bone inside the body
5. Imaging scientists develop a better tool for tracking MS
6. New insights into premature ejaculation could lead to better diagnosis and treatment
7. Better science for better fisheries management
8. Making better medicines with a handful of chemical building blocks
9. Silly Putty material inspires better batteries
10. Understanding the 1918 flu pandemic can aid in better infectious disease response
11. Green-energy community projects need better government backing
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Better tissue healing with disappearing hydrogels
(Date:7/25/2014)... molecular testing panel developed at UPMC greatly increases ... for patients with thyroid nodules and cancer, report ... (UPCI), partner with UPMC CancerCenter., The test, available ... diagnostic testing agencies, improved the chances of patients ... according to the study published this month in ...
(Date:7/24/2014)... 2014 -- Keryx Biopharmaceuticals, Inc. (Nasdaq:KERX) (the "Company") announced ... control Phase 3 study of Zerenex (ferric citrate), the ... treatment of hyperphosphatemia in patients with end-stage renal disease ... iRon delivery with FErric CiTrate in EsrD) was published ... Society of Nephrology ( JASN ). ...
(Date:7/24/2014)... disturbance has different effects on different species of ... Universities of Bristol and Exeter which tested fish ... to a flying seagull predator model when exposed ... in European minnows. , Lead author Dr ... said: "Noise levels in many aquatic environments have ...
Breaking Biology News(10 mins):Test increases odds of correct surgery for thyroid cancer patients 2Test increases odds of correct surgery for thyroid cancer patients 3Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 2Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 3Zerenex™ (ferric citrate) long-term Phase 3 study results published in JASN 4
... conditions based on results from the previous day,s sample. Scientists ... lab to culture them for analysis a process that ... engineers from the UCLA Henry Samueli School of Engineering and ... concentrations to under one hour, through the development of a ...
... A new University of Illinois study touts the ... for starterssaying that it reduces the inflammation associated with ... fiber changes the personality of immune cellsthey go from ... help us recover faster from infection," said Gregory Freund, ...
... CAMBRIDGE, Mass., March 2, 2010 Fictional candy maker ... chocolate eggs from bad, an eggucator. Likewise, by determining ... discard, scientists are aiming to find their own golden ... Toward that end, Harvard researchers and a team ...
Cached Biology News:UCLA engineers develop faster method to detect bacterial contamination in coastal waters 2UCLA engineers develop faster method to detect bacterial contamination in coastal waters 3An apple a day? Study shows soluble fiber boosts immune system 2An apple a day? Study shows soluble fiber boosts immune system 3Sorting device for analyzing biological reactions puts the power of a lab in a researcher’s pocket 2Sorting device for analyzing biological reactions puts the power of a lab in a researcher’s pocket 3
(Date:7/25/2014)... (PRWEB) July 25, 2014 WABC Radio show ... Pet with Lorry Young will be hosting California-based Vet-Stem, ... about stem cell therapy in pets. Dr. Harman first ... of stem cell therapy for pets suffering from osteoarthritis and ... Regenerative Veterinary Medicine industry forward. , Young has invited Dr. ...
(Date:7/25/2014)...  Galmed Pharmaceuticals Ltd. (Nasdaq: GLMD ) ... and commercialization of a once-daily, oral therapy for the ... financial results for the period ended June 30, 2014. ... Reported cash and cash equivalents totaling $37.4 million on ... 2013.  , Reported a net loss of $3.9 ...
(Date:7/25/2014)... 25, 2014 Sinovac Biotech Ltd. (Nasdaq: ... China , today announced that it will release ... 30, 2014, after market close on Thursday, August 14, 2014 ... the market opening on Friday, August 15, 2014, at 8:00 ... Standard Time) to review the Company,s financial results and provide ...
(Date:7/24/2014)... July 24, 2014 Gain recognition ... Supply Chain of the biotech industry. Nominations are ... Awards, brought to you by the Bio ... of supply chain management professionals for the past ... stakeholders of the Biotech industry – Manufacturers, Service ...
Breaking Biology Technology:Robert J. Harman, DVM, Founder and CEO of Vet-Stem, Inc. to Join New York Radio Host Lorry Young in Upcoming Episode of A “Paws” For Your Pet 2Robert J. Harman, DVM, Founder and CEO of Vet-Stem, Inc. to Join New York Radio Host Lorry Young in Upcoming Episode of A “Paws” For Your Pet 3Galmed Pharmaceuticals Reports First Half 2014 Financial Results 2Galmed Pharmaceuticals Reports First Half 2014 Financial Results 3Galmed Pharmaceuticals Reports First Half 2014 Financial Results 4Galmed Pharmaceuticals Reports First Half 2014 Financial Results 5Galmed Pharmaceuticals Reports First Half 2014 Financial Results 6Sinovac to Host Conference Call to Report Second Quarter 2014 Unaudited Financial Results 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 3
... , , , LEXINGTON, Mass. ... holding gmbh announced today the launch of the first human cancer ... targeted Next-Generation Sequencing (NGS). The new catalog cancer biochip features 115 ... of cancer by the Wellcome Trust Sanger Institute. , ...
... , , RARITAN, N.J., July 13 ... can accurately predict the prognosis and survival in patients ... published report in the July 10 issue of the ... retrospective study compared how well CTCs and a more ...
... , SAN MARINO, Calif., July 13 ... compounds for HIV/AIDS, autoimmune diseases, and cancer, has retired the majority ... other debt and recently issued new shares. , ... financing through the issuance of shares. This transaction originally was disclosed ...
Cached Biology Technology:First Catalog Cancer Biochip for Sequence Capture Now Available from febit 2Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer 2Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer 3Monitoring Circulating Tumor Cells With the CellSearch(R) System Can Predict Prognosis in Metastatic Breast Cancer 4Viral Genetics Retires Nearly $3.5 Million Convertible Debt and Provides Updates on Capital Structure and Stock Issuances 2Viral Genetics Retires Nearly $3.5 Million Convertible Debt and Provides Updates on Capital Structure and Stock Issuances 3
... number is a new product number, created ... showing no availability yet, please order under ... customer service for assistance. ID ... D H 100 20 mm ...
BD BioCoat Gelatin 100 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of gelatin....
Mouse monoclonal antibody raised against a full length recombinant ATF3. NCBI Entrez Gene ID = ATF3...
... Delivers 4,600 to Over 3 Million Genotypes ... is capable of performing 4,600 to over ... the GenomeLab family of products*, this automated, ... 48 SNPs in each well of an ...
Biology Products: