Navigation Links
Better blood transfusions for preterm babies
Date:11/26/2012

Results of new research from the University of Adelaide are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood.

Blood transfusions are among the most common medical procedures experienced by preterm babies, who are often anemic and suffer blood loss.

Researchers from the University of Adelaide's Robinson Institute studied 28 preterm babies (at 28 weeks' gestation or less) who were given packed red blood cell transfusions. The results of this study are now published in the journal Pediatric Research.

"Blood transfusions are a safe and life-saving medical procedure - they are an important part of modern-day medical care," says the lead author, Dr Michael Stark from the University of Adelaide's Robinson Institute.

"It has been suggested that blood transfusions themselves may be associated with medical complications that are unrelated to the reason for which the transfusion is given, and we don't really know why that is.

"These associations include bronchopulmonary dysplasia and necrotizing entercolitis, inflammatory conditions that affect the lungs and gut of very preterm babies."

The researchers have found a potential mechanism associated with the inflammatory response in the body.

"Within two to four hours of preterm babies receiving a blood transfusion, we have seen elevated levels of cytokines and chemokines - signaling cells - that stimulate inflammatory responses in the body," Dr Stark says.

"We believe that the bioactive components of packed red blood cell transfusions are initiating or amplifying these inflammatory processes in the body.

"We hope that by better understanding how the body responds to the blood, we can make improvements to blood transfusions that will reduce the likelihood of inflammatory responses. In this way, the patient will benefit from a life-saving procedure and also experience less complications as a result of that procedure.

"More research is now needed to determine exactly how this response is triggered, and how we might be able to prevent it," he says.


'/>"/>

Contact: Michael Stark
michael.stark@adelaide.edu.au
61-883-131-325
University of Adelaide
Source:Eurekalert

Related biology news :

1. Better protection for forging dies
2. A better thought-controlled computer cursor
3. A better route to xylan
4. Barley genome could hold key to better beer
5. Charting the Biosimilar and Biobetter Development Pipeline
6. Computer simulations for multiscale systems can be faster, better, more reliable
7. Engineering a better hip implant
8. New gene could lead to better bug-resistant plants
9. Ancient, bottom-dwelling critter proves: Newer isnt always better
10. Early activation of immune response could lead to better vaccines
11. For mitochondria, bigger may not be better
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/14/2017)... N.C. , Feb. 14, 2017  Wake Forest ... M.D., as its new chief executive officer (CEO). Freischlag ... CEO John D. McConnell , M.D., who last ... position at the Medical Center, after leading it since ... the full scope of Wake Forest Baptist,s academic health ...
(Date:2/10/2017)... Feb 10, 2017 Research and ... "Personalized Medicine - Scientific and Commercial Aspects" to ... ... Diagnosis is integrated with therapy for selection of treatment as ... detection and prevention of disease in modern medicine. Biochip/microarray technologies ...
(Date:2/8/2017)... BEDFORD, Mass., Feb. 7, 2017  Aware, Inc. (NASDAQ: ... services, today reported financial results for its quarter and year ... fourth quarter of 2016 was $3.9 million compared to $6.9 ... the fourth quarter of 2016 was $0.6 million compared to ... in the fourth quarter of 2016 was $0.5 million, or ...
Breaking Biology News(10 mins):
(Date:3/22/2017)... , March 22, 2017  Ascendis Pharma A/S ... innovative TransCon technology to address significant unmet medical ... for the full year ended December 31, 2016. ... for our company as we broadened our pipeline ... integrated rare disease company with an initial focus ...
(Date:3/22/2017)... -- Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ... ), a clinical-stage pharmaceutical company focused on the ... that Dr. Miriam Kidron , Oramed,s Chief ... Insulin for Diabetes Treatment: Bypassing the Roadblock," at ... Therapeutics (OPT) Boston Conference in Cambridge, Massachusetts ...
(Date:3/22/2017)... 22, 2017 MarketNewsUpdates.com News Commentary  ... The traditional ... being pressured as of late due to the rise of ... has a dramatic impact on patient,s quality of life as ... for identifying new forms of opioid formulations that prevent abuse. ...
(Date:3/22/2017)... 2017   VWR (NASDAQ: VWR), ... and service solutions to laboratory and production ... EPL Archives, Inc., an international biorepository services ... regulated product research, development and commercialization lifecycle ... ancillary services. EPL Archives is widely recognized ...
Breaking Biology Technology: