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Best treatment identified to reduce deadly Staph infections
Date:12/3/2007

LAS VEGAS One type of over-the-counter product for topical wound care is more effective than others in killing methicillin-resistant Staphylococcus aureus bacteria, or MRSA, which is potentially deadly and in recent years has moved from its historic hospital setting to a much broader public concern.

A new laboratory study indicates that many antibacterial products have some value, but a product made with benzethonium chloride kills common types of non-hospital or community associated MRSA bacteria better than other compounds. Clinical studies to confirm the results are needed, experts say.

The findings were presented today at a meeting of the American Society of Health-System Pharmacists, by David Bearden, a clinical associate professor in the College of Pharmacy at Oregon State University.

The surge in MRSA infections which have been called a superbug and medical experts say killed more people than AIDS in 2005 has alarmed health professionals. Many new cases are being found in a public, rather than health care setting, and are now attacking younger, healthier individuals. Since many of these systemic infections begin with cuts, minor wounds or skin infections, proper first aid care is taking on greater importance than ever.

A good cleaning with soap and warm water is still the first and best line of defense against infection in the cuts, scrapes and minor wounds that everyone gets, Bearden said. But theres also a place for antibacterial treatments, usually creams or ointments. With the significant increase in community-associated MRSA infections in recent years, we wanted to find out which products might work the best for this concern.

In laboratory studies, OSU scientists compared three types of compounds for their effectiveness in killing four strains of MRSA bacteria that are most commonly found in a public setting. The compounds were those made with neomycin and polymyxin; those made with polymyxin and g
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Contact: David Bearden
beardend@ohsu.edu
503-494-0116
Oregon State University
Source:Eurekalert

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