Navigation Links
Ben-Gurion U. researchers reveal connection between cancer and human evolution
Date:7/2/2009

BEER-SHEVA, ISRAEL, July 2, 2009 Researchers at Ben-Gurion University of the Negev (BGU) have discovered that gene mutations that once helped humans survive may increase the possibility for diseases, including cancer.

The findings were recently the cover story in the journal Genome Research.

The team of researchers from BGU's National Institute for Biotechnology in the Negev (NIBN) set out to look for mutations in the genome of the mitochondria, a part of every cell responsible for energy production that is passed exclusively from mothers to their children. The mitochondria are essential to every cell's survival and our ability to perform the functions of living.

"Our ancestors responded to environmental changes, such as climate shift, with mutations that increased their chances of survival. But today, these same mutations predispose us toward complex diseases such as cancer," according to researcher Dr. Dan Mishmar, a molecular biologist from the Department of Life Sciences at BGU. "Although mitochondria's role in the emergence of new species has been investigated recently, the idea that they are responsible for our susceptibility to illness startles many."

To test this hypothesis, the researchers analyzed the genome mitochondria mutations from 98 unrelated individuals. Combinations of mutations tended to occur in tumors in precisely the same DNA building blocks that changed during evolution. The team also found that the mitochondrial genome of humans who migrated out of Africa to Europe 100,000 years ago carried seven mutations found in almost all of today's Europeans.

"The concept that the same principles that drive evolution toward the emergence of new species govern the emergence of diseases is new," Mishmar explains. "A clinician looks at the genome of a tumor, or other disease, and compares it to the normal population, looking for new mutations that do not occur there. I assume the mutations are already part of the populat
'/>"/>

Contact: Andrew Lavin
andrewlavin@alavin.com
212-290-9540
American Associates, Ben-Gurion University of the Negev
Source:Eurekalert

Page: 1 2

Related biology news :

1. Ben-Gurion University research and technology used in new solar energy farm
2. Ben-Gurion University of the Negev signs collaborative contract with Bayer CropScience
3. Ben-Gurion University engineers develop technique to help combat nuclear proliferation
4. Ben-Gurion University of the Negev researchers develop new reversible, green window technology
5. Ben-Gurion University of the Negev to host
6. Ben-Gurion University of the Negev researchers help find that hypnosis can induce synesthesia
7. Environmental peace treaty between Israel and Palestinians unveiled at Ben-Gurion University
8. University of Leicester researchers discover new fluorescent silicon nanoparticles
9. OJ worse for teeth than whitening says Eastman Institute researchers
10. Stanford researchers publish comprehensive model for medical device development
11. Researchers see evidence of memory in the songbird brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... RALEIGH, N.C. , Dec. 9, 2014  Valencell, ... announced it is seeing a staggering demand from its ... demand, the Company revealed, is not solely coming from ... industries as well. "A wearable is only ... a result, accuracy is the ultimate driver in long-term ...
(Date:12/10/2014)... , Dec. 08, 2014 Research and Markets ... addition of the "Biometrics Market in Japan ... http://photos.prnewswire.com/prnh/20130307/600769 The ... such as rural banking and upgradation of the ... witnessed in the market. Besides the aforementioned projects, ...
(Date:12/5/2014)... PROVO, Utah , Dec. 4, 2014  Tute ... has raised $2.3 million in Series A1 funding led ... angel investors also participated in the investment round. ... as the healthcare community adopts next-generation sequencing and seeks ... disease," said Reid Robison , MD MBA, and ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3
... , KIEV, Ukraine, Nov. 17 Fraud and counterfeiting of ... gems, antiques and fine art, has emerged as a multi-billion ... The International Chamber of Commerce estimates that seven percent of ... new technology can give brands and consumers peace of mind ...
... of the nation,s leading public and private research universities, ... Congress, today announced the launch of ScienceWorksForUS, an initiative ... that have been made possible by the American Recovery ... the stimulus. The centerpiece of the initiative ...
... new study finds that a species of sea star stays cool ... sea stars soak up cold sea water into their bodies during ... direct sunlight at low tide. "Sea stars were assumed to ... the study,s lead author, Sylvain Pincebourde of Franois Rabelais University in ...
Cached Biology News:Innovative Document Security Technology Proves Powerful in Avoiding Counterfeit Products 2Innovative Document Security Technology Proves Powerful in Avoiding Counterfeit Products 3Members of Congress, university leaders, scientists launch ScienceWorksForUS 2Members of Congress, university leaders, scientists launch ScienceWorksForUS 3Members of Congress, university leaders, scientists launch ScienceWorksForUS 4Study: Sea stars bulk up to beat the heat 2
(Date:12/19/2014)... iLab Solutions, the global leader in core ... as the new Director of Institutional Implementations and Sarah ... two new leadership positions were created to support iLab’s ... iLab continues to meet the needs of its growing ... has been deployed at over 450 core facilities across ...
(Date:12/19/2014)... The empty capsules market is experiencing growth primarily ... innovations in the empty capsules market. The fast-growing ... of the empty capsules market. , Get Full ... Report , The report will enrich both established ... gauge the pulse of the market which in ...
(Date:12/19/2014)... 2014  Decision Resources Group finds that the ... grow moderately through 2023 as the aging population, increasing ... dental biomaterials all spur procedure volumes. Growth will be ... China and India , ... reach for a larger proportion of the population. ...
(Date:12/19/2014)... , Dec. 18, 2014   ISN has ... Safety Performance Indicators publication series. With data ... activity reported in 2013 within its online contractor management ... safety key performance indicator (KPI) statistics. ... U.S. publication is available in two industry ...
Breaking Biology Technology:iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3
... Today the National Collegiate Inventors and Innovators Alliance ... recognizing undergraduate excellence in biomedical innovation. BMEStart stands ... because of its focus on younger inventors who ... development. , The BMEStart competition welcomes submissions ...
... NEW YORK, Oct. 7 /PRNewswire-FirstCall/ - Healthnostics, Inc. ... company, announced today details regarding the social networking ... Using the Facebook(C) model that gives individuals greater ... an interactive layer that allows users to comment ...
... ... the NRA, Mike Fuljenz, President of Universal Coin & Bullion is equipping children ... Eagle GunSafe® Program. In an effort to equip law enforcement officers, teachers ... is teaming up to translate, duplicate and distribute Eddie Eagle training DVDs in ...
Cached Biology Technology:NCIIA Announces New Undergraduate Competition 2Healthnostics' Medbioworld.com Portal Web Site to Include Social Networking Features 2Mike Fuljenz and Universal Coin & Bullion Sponsors the NRA Eddie Eagle GunSafe Program 2
... unit with motorized heated lid and skirted inner ... for microarrays and chips. The four screw-down points ... force of the motorized lid is set with ... results. This interchangeable Moto Alpha unit functions on ...
... These skirted micro test tubes are ... of polypropylene, these tubes have uniform walls ... nonsterile, with separate O-ring screw caps. The ... and have an operating range from -55 ...
... carriers to suit the widest possible range ... science laboratory. Labware carriers can be placed ... is simple for the user, thanks to ... are correctly guided into position. This allows ...
... For affinity chromatography, Affi-Prep protein ... (IgG), selectively remove IgG prior to ... adsorb immune complexes for antigen purification. ... region of immunoglobulins, especially IgG from ...
Biology Products: