Many challenges remain. Kaplan and Omenetto say that key questions include how to fully replicate native silk assembly in the lab, how best to mimic silk protein sequences via genetic engineering to scale-up materials production, and how to use silk as a model polymer to spur new synthetic polymer designs that mimic natural silk's green chemistry.
Techniques for reprocessing natural silk protein in the lab continue to advance. Silks are also being cloned and expressed in a variety of hosts, including E. coli bacteria, fungi, plants and mammals, and through transgenic silkworms.
One day, efficient transgenic plants could be used to crop silk in much the same way that cotton is harvested today, the Tufts researchers note in their paper. In some regions, silk production might create a new microeconomy, as demand grows and production techniques improve.
"Based on the recent and rapid progression of silk materials from the ancient textile use into a host of new high-technology applications, we anticipate growth in the use of silks in a wide platform of applications will continue as answers to these remaining questions are obtained," say Omenetto and Kaplan.
|Contact: Kim Thurler|