Navigation Links
Behind the scenes of genetics, leukemia in Down syndrome
Date:8/8/2014

Children affected by trisomy 21 (or Down syndrome) are 50 to 500 times more likely to develop leukemia than other children. A group of geneticists working in the Faculty of Medicine at the University of Geneva (UNIGE) focused for many years on the genetic characteristics of Down syndrome. They have sequenced the exome, a specific part of our genome, in a cohort of patients affected both by Down Syndrome and Acute Lymphoblastic Leukaemia (DS-ALL), a type of cancer relative to the cells of the immune system in the bone marrow. They were able to sketch an outline of the "genetic identity card" of this disease. They found that RAS, an important oncogene in many cancers, is involved in the tumorigenesis of one third of DS-ALL cases. This work is being published in the latest issue of the journal Nature Communications.


'/>"/>
Contact: Stylianos Antonarakis
stylianos.antonarakis@unige.ch
41-223-795-708
Universit de Genve
Source:Eurekalert

Page: 1

Related biology news :

1. Revealed: The mystery behind starling flocks
2. Behind a marine creatures bright green fluorescent glow
3. The genes behind immunity
4. Scientists study biomechanics behind amazing ant strength
5. Scripps Florida scientists reveal molecular secrets behind resveratrols health benefits
6. Behind the scenes of the IPCC report, with Stanford scientists
7. Researchers reveal the dynamics behind Arctic ecosystems
8. Technofossils -- an unprecedented legacy left behind by humans
9. Is a buttery molecule behind cystic fibrosis flare-ups?
10. UA researchers find culprit behind skeletal muscle disease
11. Sharks prefer to sneak up from behind, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/4/2017)... , Jan. 4, 2017  CES 2017 – ... biometric sensor technology, today announced the launch of ... sensor systems, the highly-accurate biometric sensor modules that ... biometric technology, experience and expertise. The two new ... designed specifically for hearables, and Benchmark BW2.0, a ...
(Date:12/20/2016)... The rising popularity of mobility services ... stoking significant interest in keyless access systems. Following ... energy (BLE), biometrics and near-field communication (NFC) are ... wireless technologies in the automotive industry. This evolution ... systems opens the market to specialist companies such ...
(Date:12/16/2016)... Research and Markets has announced the addition of the "Biometric ... to their offering. ... The biometric vehicle access system market, in terms of value, ... to 2021. The market is estimated to be USD 442.7 Million ... The growth of the biometric vehicle access system market is fueled ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... , Jan. 18, 2017   Boston Biomedical ... compounds designed to target cancer stemness pathways, will feature ... compound, napabucasin, at the 2017 ASCO Gastrointestinal Cancers Symposium, ... . Napabucasin is an orally-administered ... targeting STAT3. i Cancer stem cells (CSCs) possess ...
(Date:1/18/2017)... ... January 18, 2017 , ... Total ... successfully implanted SpineFrontier’s A-CIFT™ Solofuse-P™. The operation took place on Wednesday, January 11, ... The procedure was an anterior cervical discectomy and fusion on a 42 year ...
(Date:1/18/2017)... ... , ... Researchers from a new study are stating that if levels of the ... treatment, this indicates there is still remaining prostate cancer cells that are more likely to ... has always been an indicator of whether a man’s prostate cancer is growing or ...
(Date:1/18/2017)... ... January 18, 2017 , ... Thirty-six startup companies in University City ... Pennsylvania Department of Community and Economic Development in 2016 as part of the Keystone ... University City Keystone Innovation Zone and represent the highest number of awards to the ...
Breaking Biology Technology: