Navigation Links
Behind the scenes of genetics, leukemia in Down syndrome
Date:8/8/2014

Children affected by trisomy 21 (or Down syndrome) are 50 to 500 times more likely to develop leukemia than other children. A group of geneticists working in the Faculty of Medicine at the University of Geneva (UNIGE) focused for many years on the genetic characteristics of Down syndrome. They have sequenced the exome, a specific part of our genome, in a cohort of patients affected both by Down Syndrome and Acute Lymphoblastic Leukaemia (DS-ALL), a type of cancer relative to the cells of the immune system in the bone marrow. They were able to sketch an outline of the "genetic identity card" of this disease. They found that RAS, an important oncogene in many cancers, is involved in the tumorigenesis of one third of DS-ALL cases. This work is being published in the latest issue of the journal Nature Communications.


'/>"/>
Contact: Stylianos Antonarakis
stylianos.antonarakis@unige.ch
41-223-795-708
Universit de Genve
Source:Eurekalert

Page: 1

Related biology news :

1. Revealed: The mystery behind starling flocks
2. Behind a marine creatures bright green fluorescent glow
3. The genes behind immunity
4. Scientists study biomechanics behind amazing ant strength
5. Scripps Florida scientists reveal molecular secrets behind resveratrols health benefits
6. Behind the scenes of the IPCC report, with Stanford scientists
7. Researchers reveal the dynamics behind Arctic ecosystems
8. Technofossils -- an unprecedented legacy left behind by humans
9. Is a buttery molecule behind cystic fibrosis flare-ups?
10. UA researchers find culprit behind skeletal muscle disease
11. Sharks prefer to sneak up from behind, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... and LONDON , ... Finacle, part of EdgeVerve Systems, a product subsidiary ... Onegini today announced a partnership to integrate the ...      (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ) ... provide their customers enhanced security to access and ...
(Date:4/14/2016)... April 14, 2016 BioCatch ... Detection, today announced the appointment of Eyal Goldwerger ... role. Goldwerger,s leadership appointment comes at a ... of the deployment of its platform at several of ... technology, which discerns unique cognitive and physiological factors, is ...
(Date:3/23/2016)... WAKEFIELD, Massachusetts , March 23, 2016 ... kombiniert im Interesse erhöhter Sicherheit Gesichts- und ... Xura, Inc. (NASDAQ: MESG ... heute bekannt, dass das Unternehmen mit SpeechPro ... insbesondere aus der Finanzdienstleistungsbranche, wird die Möglichkeit ...
Breaking Biology News(10 mins):
(Date:5/27/2016)... and READING, England , ... Indegene ( http://www.indegene.com ), ein führender Anbieter ... die Life-Science-Branche, Pharmaunternehmen und Gesundheitsorganisationen, und TranScrip ... von innovativen wissenschaftlichen Support-Services für den gesamten ... IntraScience heute den Ausbau ihrer bestehenden Allianz ...
(Date:5/26/2016)... 26, 2016  Agriculture nutrients are in the news ... is running their nitrate removal system on ... and coastal regions nationwide are painting the ... widespread issue. NECi Superior Enzymes, a biotechnology ... developed a new, easy to use device that fits ...
(Date:5/26/2016)... Q BioMed Inc. (OTCQB: QBIO), a biotechnology acceleration ... at the 5th Annual Marcum MicroCap Conference on Thursday, June ... at the Grand Hyatt Hotel. The Company,s presentation ... scheduled to begin at 11a.m ET in the Broadway Room. ... and outline milestones for the balance of 2016 and beyond. ...
(Date:5/26/2016)... ... May 26, 2016 , ... After several promising treatments in ... the City of Knowledge in Panama, a 6 year-old Duchenne’s muscular dystrophy patient ... this year following FDA approval of a second application for a single patient, ...
Breaking Biology Technology: