Navigation Links
Beaumont awarded grants to study sports-related injury treatment, improve recovery
Date:4/22/2014

Two orthopedic organizations have presented Beaumont Health System with prestigious, competitive research grants that could improve patients' recovery from both athletic and nonathletic injuries.

The American Orthopaedic Society for Sports Medicine awarded a $40,000 grant to fund stem cell-based research that could help prevent osteoarthritis after sports injuries like a ruptured knee anterior cruciate ligament, or ACL. According to the National Institutes of Health, "An anterior cruciate ligament injury is the over-stretching or tearing of the anterior cruciate ligament in the knee. A tear may be partial or complete." These kinds of injuries typically happen when someone hits the side of an athlete's knee or when an athlete stops quickly and changes direction while running, jumping or turning. This type of injury occurs more frequently in women.

Beaumont researchers and doctors will study how the body's stem cells react to an ACL rupture. Then, they will search for ways to redirect those stem cells to help the injury heal, without removing the stem cells from the patient's body. It's called "in situ" tissue engineering.

"When we say in situ tissue engineering, we are saying that we can initiate the regeneration and/or healing of tissues without doing anything outside of the body. Our approach involves the administration of a drug that causes the patient's stem cells to leave bone marrow temporarily and enter the circulation. We then deliver a signal, called a chemokine, locally that recruits those circulating stem cells to the desired site. Once they get there, we have scaffolds that will give the stem cells cues on how to heal or regenerate an injured tissue," says Orthopaedic Research Laboratories Director Kevin Baker, Ph.D.

At Beaumont Hospital, Royal Oak, orthopedic surgeons perform more than 14,000 surgical procedures every year. Beaumont Health System is leading the research, but also collaborating with the University of Michigan.

In addition, the American Orthopaedic Foot and Ankle Society awarded a $20,000 grant to study another stem cell-based technique that could improve patients' ability to heal from the rupture of an Achilles tendon. According to the NIH, "The Achilles tendon connects your calf muscles to your heel bone. Together, they help you push your heel off the ground and go up on your toes. You use these muscles and your Achilles tendon when you walk, run, and jump." After a rupture, an athlete's recovery time can stretch anywhere from a few weeks to an entire season. All research for this grant will take place at Beaumont Health System.

Dr. Baker expects to have some results from the studies within the next year. However, the research will continue well beyond that timeframe. "I think we have a real potential to bring a new treatment into the clinics and operating rooms, which will require extensive preclinical and clinical testing," Dr. Baker says.

The Following Individuals Collaborated On The Projects:

Post-Traumatic Osteoarthritis (Grant from American Orthopaedic Society for Sports Medicine):

  • Perry Altman, MD (Beaumont)

  • Kyle Anderson, MD (Beaumont)

  • Kevin Baker, Ph.D (Beaumont)

  • Asheesh Bedi, MD (U-Michigan)

  • Tristan Maerz, MS (Beaumont)

Achilles Tendon Repair (Grant from American Orthopaedic Foot & Ankle Society):

  • Erin Baker, MS (Beaumont)

  • Kevin Baker, PhD (Beaumont)

  • Shannon Carpenter, MD (Beaumont)

  • Paul Fortin, MD (Beaumont)


'/>"/>
Contact: Mark Geary
Mark.Geary@beaumont.edu
Beaumont Health System
Source:Eurekalert

Related biology news :

1. Beaumont named to 2013 InformationWeek 500 list of top technology innovators
2. 5 NSF Graduate Research Fellowships awarded to UH students, alumna
3. UTMB scientist awarded $150,000 by March of Dimes
4. Researcher awarded $1 million for stress-associated disease and aging research
5. Scripps Florida scientist awarded $1.5 million to design therapeutics with new RNA approach
6. NJIT professor awarded patent today for new desalination devices, more
7. Scripps Florida scientists awarded $8.4 million grant to develop new anti-smoking treatments
8. Mason environmentalist awarded Blue Planet Prize for lifetime achievement in conservation
9. NOAA scholarship awarded to Jan Vicente to study the impact of ocean acidification on marine sponges
10. VESAG mHealth watch awarded CE, ROHS and SAR certifications
11. Danforth Center awarded $12 million to study drought
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology: