Navigation Links
'Beating' heart machine expedites research and development of new surgical tools, techniques
Date:5/12/2009

A new machine developed at North Carolina State University makes an animal heart pump much like a live heart after it has been removed from the animal's body, allowing researchers to expedite the development of new tools and techniques for heart surgery. The machine saves researchers time and money by allowing them to test and refine their technologies in a realistic surgical environment, without the cost and time associated with animal or clinical trials.

Currently, most medical device prototypes designed for use in heart surgery are tested on live pigs, which have heart valves that are anatomically similar to human heart valves. However, these tests are both expensive and time-consuming, and involve a lengthy permission process to ensure that the use of live animals is necessary. So, researchers at NC State have developed a "dynamic heart system" a machine that pumps fluid through a pig heart so that it functions in a very realistic way. "Researchers can obtain pig hearts from a pork processing facility and use the system to test their prototypes or practice new surgical procedures," says Andrew Richards, a Ph. D. student in mechanical engineering at NC State who designed the heart machine.

The computer-controlled machine, which operates using pressurized saline solution, also allows researchers to film the interior workings of the pumping heart enabling them to ascertain exactly which surgical technologies and techniques perform best for repairing heart valves.

By using the machine, researchers can determine if concepts for new surgical tools are viable before evaluating them on live animals. They can also identify and address any functional problems with new technological tools. "There will still be a need for testing in live animal models," says Dr. Greg Buckner, who directed the project, "but this system creates an intermediate stage of testing that did not exist before. It allows researchers to do 'proof of concept' evaluations, and refine the designs, before operating on live animals." Buckner is an associate professor of mechanical and aerospace engineering at NC State.

Using the system could also save researchers a great deal of money. Once the machine is purchased and set up, the cost of running experiments is orders of magnitude less expensive than using live animals. "It costs approximately $25 to run an experiment on the machine," says Richards, "whereas a similar experiment using a live animal costs approximately $2,500."


'/>"/>

Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University
Source:Eurekalert  

Related biology news :

1. Study offers clues to beating hearing loss
2. Building disease-beating wheat
3. Heart protein regulates blood vessel maintenance
4. Chemical found in medical devices impairs heart function
5. Heart attacks: The tipping point
6. Gladstone scientists identify key factors in heart cell creation
7. Eating fatty fish once a week reduces mens risk of heart failure
8. A missing enzyme conveys major heart protection in pre-clinical work
9. Inhaling a heart attack: How air pollution can cause heart disease
10. Simple test helps predict heart attack risk
11. Why lazy Susan has a weak heart
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Beating' heart machine expedites research and development of new surgical tools, techniques
(Date:6/3/2016)... , June 3, 2016 ... von Nepal hat ... Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung ... in der Produktion und Implementierung von Identitätsmanagementlösungen. ... Ausschreibung im Januar teilgenommen, aber Decatur wurde ...
(Date:6/1/2016)... NEW YORK , June 1, 2016 ... Biometric Technology in Election Administration and Criminal Identification to ... According to a recently released TechSci Research report, " ... Sector, By Region, Competition Forecast and Opportunities, 2011 - ... $ 24.8 billion by 2021, on account of growing ...
(Date:5/12/2016)... May 12, 2016 WearablesResearch.com , a ... the overview results from the Q1 wave of its ... wave was consumers, receptivity to a program where they ... a health insurance company. "We were surprised ... says Michael LaColla , CEO of Troubadour Research, ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016   EpiBiome , ... secured $1 million in debt financing from Silicon Valley ... up automation and to advance its drug development efforts, ... new facility. "SVB has been an incredible ... the services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample tracking software company, ... Crime Laboratory, has joined STACS DNA as a Field Application Specialist. , “I ... President and COO of STACS DNA. “In further expanding our capacity as a scientific ...
(Date:6/23/2016)... 2016 Apellis Pharmaceuticals, Inc. today announced ... of its complement C3 inhibitor, APL-2. The trials ... dose studies designed to assess the safety, tolerability, ... in healthy adult volunteers. Forty subjects ... single dose (ranging from 45 to 1,440mg) or ...
(Date:6/23/2016)... 23, 2016 Andrew ... http://doi.org/10.17925/OHR.2016.12.01.22 Published recently in ... journal from touchONCOLOGY, Andrew D Zelenetz , ... cancer care is placing an increasing burden on ... biologic therapies. With the patents on many biologics ...
Breaking Biology Technology: