Navigation Links
'Beating' heart machine expedites research and development of new surgical tools, techniques

A new machine developed at North Carolina State University makes an animal heart pump much like a live heart after it has been removed from the animal's body, allowing researchers to expedite the development of new tools and techniques for heart surgery. The machine saves researchers time and money by allowing them to test and refine their technologies in a realistic surgical environment, without the cost and time associated with animal or clinical trials.

Currently, most medical device prototypes designed for use in heart surgery are tested on live pigs, which have heart valves that are anatomically similar to human heart valves. However, these tests are both expensive and time-consuming, and involve a lengthy permission process to ensure that the use of live animals is necessary. So, researchers at NC State have developed a "dynamic heart system" a machine that pumps fluid through a pig heart so that it functions in a very realistic way. "Researchers can obtain pig hearts from a pork processing facility and use the system to test their prototypes or practice new surgical procedures," says Andrew Richards, a Ph. D. student in mechanical engineering at NC State who designed the heart machine.

The computer-controlled machine, which operates using pressurized saline solution, also allows researchers to film the interior workings of the pumping heart enabling them to ascertain exactly which surgical technologies and techniques perform best for repairing heart valves.

By using the machine, researchers can determine if concepts for new surgical tools are viable before evaluating them on live animals. They can also identify and address any functional problems with new technological tools. "There will still be a need for testing in live animal models," says Dr. Greg Buckner, who directed the project, "but this system creates an intermediate stage of testing that did not exist before. It allows researchers to do 'proof of concept' evaluations, and refine the designs, before operating on live animals." Buckner is an associate professor of mechanical and aerospace engineering at NC State.

Using the system could also save researchers a great deal of money. Once the machine is purchased and set up, the cost of running experiments is orders of magnitude less expensive than using live animals. "It costs approximately $25 to run an experiment on the machine," says Richards, "whereas a similar experiment using a live animal costs approximately $2,500."


Contact: Matt Shipman
North Carolina State University

Related biology news :

1. Study offers clues to beating hearing loss
2. Building disease-beating wheat
3. Heart protein regulates blood vessel maintenance
4. Chemical found in medical devices impairs heart function
5. Heart attacks: The tipping point
6. Gladstone scientists identify key factors in heart cell creation
7. Eating fatty fish once a week reduces mens risk of heart failure
8. A missing enzyme conveys major heart protection in pre-clinical work
9. Inhaling a heart attack: How air pollution can cause heart disease
10. Simple test helps predict heart attack risk
11. Why lazy Susan has a weak heart
Post Your Comments:
Related Image:
'Beating' heart machine expedites research and development of new surgical tools, techniques
(Date:11/17/2015)... 17, 2015  Vigilant Solutions announces today that Mr. ... of Directors. --> --> ... from the partnership at TPG Capital, one of the ... $140 Billion in revenue.  He founded and led TPG,s ... TPG companies, from 1997 to 2013.  In his first ...
(Date:11/16/2015)... JOSE, Calif. , Nov 16, 2015 /PRNewswire/ ... developer of human interface solutions, today announced expansion ... Synaptics TouchView ™ touch controller and display ... architectural revolution of smartphones. These new TDDI products ... include TD4100 (HD resolution), TD4302 (WQHD resolution), and ...
(Date:11/12/2015)...  Arxspan has entered into an agreement with ... use of its ArxLab cloud-based suite of biological ... will support the institute,s efforts to electronically manage ... internally and with external collaborators. The ArxLab suite ... Institute,s electronic laboratory notebook, compound and assay registration, ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... TEL AVIV, Israel , Nov. 24, 2015  Tikcro Technologies Ltd. ... be held on December 29, 2015 at 11:00 a.m. Israel ... & Co., Electra Tower, 98 Yigal Allon Street, 36 th Floor, ... , election of Eric Paneth and Izhak Tamir ... and Rami Skaliter as external directors; , approval of an ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... InSphero AG, ... 3D cell culture models, has promoted Melanie Aregger to serve as Chief Operating Officer. ... Aregger served on the management team and was promoted to Head of ...
(Date:11/24/2015)... 24, 2015 HemoShear Therapeutics, LLC, a ... for metabolic disorders, announced today the appointment of ... of Directors (BOD). Mr. Watkins is the former ... Sciences (HGS), and also served as the chairman ... Powers , Chairman and CEO of HemoShear Therapeutics. ...
(Date:11/24/2015)... NEW YORK , Nov. 24, 2015 According ... today than in 2005. This is something that many doctors, ... long time. One questions remains: with fewer PSA tests being ... cancer ? Dr. David Samadi, "Despite ... cancer, the disease remains the second leading cancer cause of ...
Breaking Biology Technology: