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Baylor, DNAnexus, Amazon Web Services collaboration enables largest-ever cloud-based analysis of genomic data
Date:10/25/2013

HOUSTON (Oct. 25, 2013) With their participation in the completion of the largest cloud-based analysis of genome sequence data, researchers from the Baylor College of Medicine Human Genome Sequencing Center are helping to usher genomic scientists and clinicians around the world into a new era of high-level data analysis. (A "cloud" is a virtual network of remote internet servers used to store, manage and process information.)

"The mission of the Baylor Human Genome Sequencing Center is to drive genomics and genomic analysis to be at the leading edge of everything in the field," said Dr. Jeffrey Reid, assistant professor in the Human Genome Sequencing Center at BCM, who led the BCM portion of the project. "In terms of analysis, the future of genomic research and genomic medicine is in the cloud. We are very much going towards more computing and not less."

Together with the Platform-as-a-Service company DNAnexus and Amazon Web Services, the largest provider of cloud computing, BCM sequenced the DNA of more than 14,000 individuals -- 3,751 whole genomes and 10,771 whole exomes using next generation sequencing. (An exome contains all the genes in a genome and are the part of the genome that provides the blueprints for proteins.) The individuals whose genetic material was sequenced are part of the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium or CHARGE project aimed at advancing understanding of human genetics and the contributions to heart disease and aging.

Reid gave a presentation on the project today (Oct. 25) at the American Society of Human Genetics annual meeting in Boston.

The BCM Human Genome Sequencing Center-developed Mercury pipeline, a semi-automated and modular set of tools for the analysis of next generation sequencing data in both re
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Contact: Glenna Picton
picton@bcm.edu
713-798-4710
Baylor College of Medicine
Source:Eurekalert

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