Navigation Links
Barrow scientist receives $450K MDA grant
Date:4/5/2010

(April 5, 2010) -- A scientist at Barrow Neurological Institute in Phoenix has been awarded a major grant from the Muscular Dystrophy Association (MDA) to continue his groundbreaking work in the disease of myasthenia gravis.

The $450,000 grant is part of MDA's ongoing commitment to fund neuromuscular research that may eventually lead to treatments and cures for muscular dystrophy and related diseases. Including this funding, the MDA has awarded Fu-Dong Shi more than $1.1 million since 2001.

"Dr. Shi is an outstanding scientist and Fu-Dong's contributions to the field of neuromuscular disease research continue to be impressive," said R. Rodney Howell, MD, Chairman of the MDA Board of Directors.

In myasthenia gravis, the body's own immune system mistakenly attacks the place where nerve signals normally reach muscle fibers, leading to fatigue and muscle weakness.

This "autoimmune" disease can be treated by general suppression of the immune system and other therapies. However, a treatment that specifically targets only the actions of the immune system that causes the disease would be highly desirable.

Shi and his colleagues at Barrow, which is part of St. Joseph's Hospital and Medical Center, will now focus on Th17 cells; recent research has shown they may play a key role in causing or intensifying autoimmunity.

"The advancement of biology and immunology in recent years now allows us to tackle very specific elements of our immune system (for example, Th-17 cells, regulatory T cells, etc.) and make corrections and adjustments, so that production of disease-causing antibodies can be reduced or eliminated," said Shi. "For several years, our group has been focusing on these targeted therapies. We feel now that we are closer than ever to achieving this goal."

Shi was one of 42 medical researchers and their labs who received awards totaling over $21 million by the Muscular Dystrophy Association to continue critical neuromuscular research. Many of the grants are multi-year awards to be dispersed over the next three years.


'/>"/>

Contact: Lynne Reaves
lynne.reaves@chw.edu
602-406-4734
St. Joseph's Hospital and Medical Center
Source:Eurekalert

Related biology news :

1. New era of pain drugs advanced by Barrow researcher
2. Barrow researcher finds natural hydrogel helps heal spinal cord
3. Barrow scientist awarded $400,000 grant to study cell associated with intuition and autism
4. Barrow scientists solve 200-year-old scientific debate involving visual illusions
5. International team of scientists describe first Cretaceous African amber deposit
6. Leading conservation scientists awarded prestigious 2010 Tyler Environmental Prize
7. Tiny gold probes give scientists a sense of how disease develops
8. Scientists link climate change and Atlantic croaker fishery
9. Queens scientists boost endangered freshwater mussels population
10. US women and minority scientists discouraged from pursuing STEM careers, national survey shows
11. Fishing discard ban could damage sea bird success, scientists warn
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2016)... WARSAW, Poland , Nov. 30, 2016 Not many of us ... most crucial aspects of recovery so we need to do it well. Inadequate sleep ... heart problems, high blood pressure, stroke, diabetes, and even cancer. Maybe now ... a Christmas present that could help them to manage their sleep quality? ... ...
(Date:11/29/2016)... VILNIUS, Lithuania , Nov. 29, 2016 ... high-precision biometric identification and object recognition technologies, ... kit (SDK) for fingerprint recognition solutions that ... extract a fingerprint template using less than ... used in compact devices that have limited ...
(Date:11/24/2016)... Cercacor today introduced Ember TM Sport ... non-invasively measure hemoglobin, Oxygen Content, Oxygen Saturation, Perfusion ... in approximately 30 seconds. Smaller than a smartphone, using ... to key data about their bodies to help monitor ... Hemoglobin carries oxygen to muscles. When hemoglobin ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... Dec. 8, 2016  Biotheranostics today announced that ... of the Breast Cancer Index (BCI) in identifying ... are most at-risk for disease recurrence and might ... from three studies advancing the understanding of the ... tumor biology and inform decisions related to patient ...
(Date:12/8/2016)... ... December 08, 2016 , ... Opal Kelly, a leading ... interconnect using USB or PCI Express, announced the FOMD-ACV-A4, the company's first FPGA-on-Module ... small, thin, SODIMM-style module that fits a standard 204-pin SODIMM socket for low-cost ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... ... data bioInformatics portal. In response to client demand KbioBox developed a sophisticated “3 ... biodesign program. Both are accessible from KBioBox’s new website, https://www.kbiobox.com/ ...
(Date:12/8/2016)... N.J. , Dec. 8, 2016  Soligenix, ... late-stage biopharmaceutical company focused on developing and commercializing ... an unmet medical need, announced today the long-term ... with SGX942 (dusquetide), a first-in-class Innate Defense Regulator ... in head and neck cancer patients undergoing chemoradiation ...
Breaking Biology Technology: