Navigation Links
Barrow researcher finds natural hydrogel helps heal spinal cord
Date:9/17/2009

Research led by a scientist at the Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has shown injecting biomaterial gel into a spinal cord injury site provides significantly improved healing. The project that also included researchers from Purdue University and Arizona State University indicates that a "practical path" to treatment may be found for spinal injury patients.

The research led by the Mark Preul, MD of Barrow and Alyssa Panitch, PhD of Purdue was published in the Journal of Neurosurgery. Their study found that injection of an engineered hydrogel made up mainly of hyaluronic acid (a naturally-occurring body substance) into the spinal cord injury site decreases scarring and promotes a realignment of the spinal cord fibers around the injury site.

The hyaluronic acid which forms a scaffold-like configuration may help to structurally stabilize the spinal cord injury site. Tracing of cells in the brain stem after injury showed much higher levels in the hydrogel treated animals compared to animals which did not receive the treatment, and approached nearly normal levels. Treated animals had higher functional scores than non-treated animals.

The work was presented at the Annual Meeting of the American Association of Neurological Surgeons in San Diego where it won the Synthes Prize for Spine Research.

"Spinal cord injury is devastating to civilian and military populations especially to the young. There has been little progress toward paradigms of regeneration and few results that show real, sustained functional recovery," says Dr. Preul. "We've been so pre-occupied with regeneration, but that is a highly complicated and difficult to define goal. This project is a synergy of neurosurgeons and bioengineers that attempts repair of the SCI lesion cavity using a tissue-engineering biomaterials approach."

Dr. Preul says his team's goal is to find ways to structurally allow the body to better heal itself. "In this project we did not add anything to the hyaluronic acid. It may be that adding growth factors or cells into the gel matrix may allow even better results."

Although clinical trials are likely years off, Dr. Preul says these results show "we may be on a practical path that can give hope to the many people who suffer this sort of injury."


'/>"/>

Contact: Lynne Reaves
lreaves@chw.edu
602-406-4734
St. Joseph's Hospital and Medical Center
Source:Eurekalert

Related biology news :

1. Barrow scientists solve 200-year-old scientific debate involving visual illusions
2. Barrow scientist awarded $400,000 grant to study cell associated with intuition and autism
3. Researchers identify proteins involved in new neurodegenerative syndrome
4. Texas researchers and educators head for Antarctica
5. MGH researchers describe new way to identify, evolve novel enzymes
6. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
7. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
8. U of MN researchers discover noninvasive diagnostic tool for brain diseases
9. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
10. Researchers discover new strategies for antibiotic resistance
11. Researchers find new taste in fruit flies: carbonated water
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2016)... 20, 2016  Synaptics Incorporated (NASDAQ: SYNA ... today announced sampling of S1423, its newest ClearPad ... small screen applications including smartwatches, fitness trackers, and ... and rectangular shapes, as well as thick and ... moisture on screen, while wearing gloves, and supports ...
(Date:1/15/2016)... , Jan. 15, 2016 Recent publicized ... small to find new ways to ensure data security ... iOS and Android that ties ... biometrics, transforming it into a hardware authorization token. Customer ... swipe their fingerprint on their KodeKey enabled device to ...
(Date:1/13/2016)... , January 13, 2016 /PRNewswire/ ... announced the addition of the  "India ... Estimation & Forecast (2015-2020)"  report ... http://www.researchandmarkets.com/research/7h6hnn/india_biometrics ) has announced the addition ... Identification Market - Estimation & Forecast ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... Information Management ... Web product. The upgrade represents a completely new technical foundation and is so ... offer a responsive design interface, significantly increased speed for search results, a streamlined layout ...
(Date:2/8/2016)... Feb. 8, 2016  Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today that its new website has ... resource–user-centric, story-driven, knowledge-based and mobile-friendly. Visit the new ... ... ... "The goal was to reimagine ...
(Date:2/5/2016)... , Feb. 5, 2016  In the pharmaceutical ... for a host of launch activities including the identification ... this launch activity is especially high in the oncology ... Best Practices and the Role of Medical Affairs ... companies focused on oncology therapies find better ways to ...
(Date:2/4/2016)... - New FDA action date of July 22, ... July 22, 2016   --> - ...   - Lifitegrast has the potential to be the ... signs and symptoms of dry eye disease in adults ... product approved in the U.S. in the past decade indicated for the treatment of ...
Breaking Biology Technology: