Navigation Links
Barrow researcher finds natural hydrogel helps heal spinal cord
Date:9/17/2009

Research led by a scientist at the Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has shown injecting biomaterial gel into a spinal cord injury site provides significantly improved healing. The project that also included researchers from Purdue University and Arizona State University indicates that a "practical path" to treatment may be found for spinal injury patients.

The research led by the Mark Preul, MD of Barrow and Alyssa Panitch, PhD of Purdue was published in the Journal of Neurosurgery. Their study found that injection of an engineered hydrogel made up mainly of hyaluronic acid (a naturally-occurring body substance) into the spinal cord injury site decreases scarring and promotes a realignment of the spinal cord fibers around the injury site.

The hyaluronic acid which forms a scaffold-like configuration may help to structurally stabilize the spinal cord injury site. Tracing of cells in the brain stem after injury showed much higher levels in the hydrogel treated animals compared to animals which did not receive the treatment, and approached nearly normal levels. Treated animals had higher functional scores than non-treated animals.

The work was presented at the Annual Meeting of the American Association of Neurological Surgeons in San Diego where it won the Synthes Prize for Spine Research.

"Spinal cord injury is devastating to civilian and military populations especially to the young. There has been little progress toward paradigms of regeneration and few results that show real, sustained functional recovery," says Dr. Preul. "We've been so pre-occupied with regeneration, but that is a highly complicated and difficult to define goal. This project is a synergy of neurosurgeons and bioengineers that attempts repair of the SCI lesion cavity using a tissue-engineering biomaterials approach."

Dr. Preul says his team's goal is to find ways to structurally allow the body to better heal itself. "In this project we did not add anything to the hyaluronic acid. It may be that adding growth factors or cells into the gel matrix may allow even better results."

Although clinical trials are likely years off, Dr. Preul says these results show "we may be on a practical path that can give hope to the many people who suffer this sort of injury."


'/>"/>

Contact: Lynne Reaves
lreaves@chw.edu
602-406-4734
St. Joseph's Hospital and Medical Center
Source:Eurekalert

Related biology news :

1. Barrow scientists solve 200-year-old scientific debate involving visual illusions
2. Barrow scientist awarded $400,000 grant to study cell associated with intuition and autism
3. Researchers identify proteins involved in new neurodegenerative syndrome
4. Texas researchers and educators head for Antarctica
5. MGH researchers describe new way to identify, evolve novel enzymes
6. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
7. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
8. U of MN researchers discover noninvasive diagnostic tool for brain diseases
9. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
10. Researchers discover new strategies for antibiotic resistance
11. Researchers find new taste in fruit flies: carbonated water
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... ANGELES , June 22, 2016 /PRNewswire/ ... identity management and verification solutions, has partnered ... edge software solutions for Visitor Management, Self-Service ... provides products that add functional enhancements ... partnership provides corporations and venues with an ...
(Date:6/21/2016)... British Columbia , June 21, 2016 /PRNewswire/ ... appointed to the new role of principal product ... been named the director of customer development. Both ... NuData,s chief technical officer. The moves reflect NuData,s ... teams in response to high customer demand and ...
(Date:6/16/2016)... 16, 2016 The global ... to reach USD 1.83 billion by 2024, according ... Inc. Technological proliferation and increasing demand in commercial ... to drive the market growth.      ... The development of advanced multimodal techniques for biometric ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension of ... higher end machines that use the more unconventional z-dimension of 20mm. Z-dimension ... of the cuvette holder. , FireflySci has developed several Agilent flow cell product ...
(Date:6/23/2016)... Seattle, WA (PRWEB) , ... June 23, 2016 ... ... technology, announces the release of its second eBook, “Clinical Trials Patient Recruitment and ... patient recruitment and retention in this eBook by providing practical tips, tools, and ...
(Date:6/23/2016)... CAMBRIDGE, Mass. , June 23, 2016 /PRNewswire/ ... the development of novel compounds designed to target ... compound, napabucasin, has been granted Orphan Drug Designation ... in the treatment of gastric cancer, including gastroesophageal ... cancer stemness inhibitor designed to inhibit cancer stemness ...
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
Breaking Biology Technology: