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Baffling blood problem explained
Date:3/20/2013

SMIM1.

Next, Arnaud's team in France tested seventy people known to be Vel-negative. In every case, they found a deletiona tiny missing chunk of DNAin the gene that instructs cells on how to manufacture SMIM1. This was the final proof the scientists needed to show that the Vel-negative blood type is caused by a lack of the SMIM1 protein on a patient's red blood cells.

Today, personalized medicine where doctors treat us based on our unique biological makeupis a hot trend. "The science of blood transfusion has been attempting personalized medicine since its inception," Ballif notes, "given that its goal is to personalize a transfusion by making the best match possible between donor and recipient."

"Identifying and making available rare blood types such as Vel-negative blood brings us closer to a goal of personalized medicine," he says. "Even if you are that rare one person out of 2,500 that is Vel-negative, we now know how to rapidly type your blood and find blood for youshould you need a transfusion."


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Contact: Joshua Brown
joshua.e.brown@uvm.edu
802-656-3039
University of Vermont
Source:Eurekalert  

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