Navigation Links
Bacterial slime helps cause serious disease
Date:5/4/2008

Leptospirosis is a serious but neglected emerging disease that infects humans through contaminated water. Now research published in the May issue of the journal Microbiology shows for the first time how bacteria that cause the disease survive in the environment.

Leptospirosis is a major public health problem in South East Asia and South America, with over 500,000 severe cases every year. Between 5% and 20% of these cases are fatal. Rats and other mammals carry the disease-causing pathogen Leptospira interrogans in their kidneys. When they urinate, they contaminate surface water with the bacteria, which can survive in the environment for long periods.

This led us to see if the bacteria build a protective casing around themselves for protection, said Professor Mathieu Picardeau from the Institut Pasteur in Paris, France. Previously, scientists believed the bacteria were planktonic, living freely in the water. But Professor Picardeau and his team have shown that L. interrogans can make biofilms, which could be one of the main factors controlling survival and disease transmission.

Many different bacteria make biofilms, which protect them against harsh conditions and make them more resistant to antibiotics. They do this by producing a slime, in which the colony can grow unharmed. 90% of the species of Leptospira we tested could form biofilms. It takes L. interrogans an average of 20 days to make a biofilm, said Professor Picardeau.

This ability may contribute to the long-term survival of the bacteria in environmental water and even help them cause disease in humans. Biofilm formation might also play an important role in keeping the bacteria alive in the kidneys of animals such as rats without causing disease.

This finding is a step forward in our understanding of Leptospirosis. We now need to study the mechanism of biofilm formation in both fresh water and renal tubules in animal kidneys, said Professor Picardeau. We hope our research will lead to the identification of new strategies to diagnose and prevent this neglected emerging disease.


'/>"/>

Contact: Lucy Goodchild
l.goodchild@sgm.ac.uk
44-011-898-81843
Society for General Microbiology
Source:Eurekalert

Related biology news :

1. Tomato pathogen genome may offer clues about bacterial evolution
2. Biologists surprised to find parochial bacterial viruses
3. Biochemists reveal details of mysterious bacterial microcompartments
4. Tomato pathogen genome may offer clues about bacterial evolution at dawn of agriculture
5. Bacterial infections in premature babies more common than previously realized
6. New drug targets may fight tuberculosis and other bacterial infections in novel way
7. Small RNA plays parallel roles in bacterial metabolism
8. Scripps research team blocks bacterial communication system to prevent deadly staph infections
9. Legionnaires bacterial proteins work together to survive
10. Deadly dose: Rensselaer heparin expert helps uncover source of lethal contamination
11. Underwater microscope helps prevent shellfish poisoning along Gulf Coast of Texas
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/2/2016)... VIEW, Calif. , Feb. 2, 2016 /PRNewswire/ ... retinopathy market, Frost & Sullivan recognizes US-based Intelligent ... America Frost & Sullivan Award for New Product ... provider in North America , ... in the rapidly growing diabetic retinopathy market. The ...
(Date:1/27/2016)...  Rite Track, Inc. a leading semiconductor equipment and ... Ohio announced today the acquisition of PLUS LLC. ... Austin, Texas , will significantly bolster ... installations and technical support offerings for TEL Track Systems. ... "PLUS has provided world class service including refurbishment, enhancements ...
(Date:1/21/2016)... 21, 2016 --> ... market research report "Emotion Detection and Recognition Market by Technology ... (Facial Expression, Voice Recognition and Others), Services, Application ... to 2020", published by MarketsandMarkets, the global Emotion ... USD 22.65 Billion by 2020, at a CAGR ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... (PRWEB) , ... February 10, ... ... REGN) today announced that it has joined the Human Vaccines Project, a ... infectious diseases and cancer. , The Human Vaccines Project brings together ...
(Date:2/10/2016)... plc (NYSE: AGN ) a leading global pharmaceutical ... CEO and President, will be featured as the keynote ... Capital Markets Healthcare Conference on Tuesday, February 23, 2016 ... Hotel in New York, NY . ... accessed on Allergan,s Investor Relations web site at ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... announced today the promotion of two long-standing principal investigators (PI) to the roles ... Clinical Research and Development. , Dr. Laurence Chu, a Benchmark Research PI in ...
(Date:2/10/2016)... ... February 10, 2016 , ... LATHAM, NEW YORK... Marktech Optoelectronics ... West conference in San Francisco’s Moscone Center from February 16-18, 2016, and at ... , These latest InGaAs PIN diode standard packages feature a TO-46 metal can with ...
Breaking Biology Technology: