Navigation Links
Bacteria 'launch a shield' to resist attack
Date:11/1/2009

Researchers from the University of Copenhagen and the Technical University of Denmark along with other collaborators in Denmark and the US found that the bacterium Pseudomonas aeruginosa can 'switch on' production of molecules that kill white blood cells preventing the bacteria being eliminated by the body's immune system.

P. aeruginosa is responsible for many hospital-acquired infections and also causes chronic infections in those with pre-existing medical conditions such as cystic fibrosis (CF). The bacteria cause persistent lung infections by clumping together to form a biofilm, which spreads over the lungs like a slime. Such biofilms are generally resistant to antibiotics as well as the host immune response.

The study showed that P. aeruginosa uses a well-studied communication system called quorum sensing (QS) to detect approaching white blood cells and warn other bacteria in the biofilm. In response to this signal, the bacteria increase their production of molecules called rhamnolipids. These molecules sit on the biofilm surface to form a shield that destroys any white blood cells that encounter it. Interrupting quorum sensing to halt the "launch a shield" response could be a way of treating these bacteria that can resist antibiotics as well as the host immune system.

Professor Michael Givskov from the University of Copenhagen who led the study believes there are significant clinical benefits to this research. "The ultimate goal [of this research] is to eradicate the present day's antibiotic-resistant bacteria that are involved in the bulk of chronic infections," he says. "Antibiotic resistance is one of the most serious emerging health problems in the world today. More than 70% of the disease-causing bacteria are resistant to at least one of the currently available antibiotics. Studying interactions between P. aeruginosa and the innate and adaptive immune response will provide valuable information
'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Boston University scientists first to see RNA network in live bacterial cells
2. Eating right, not supplements, is best at keeping your good bacteria healthy, dietitian says
3. Researchers discover RNA repair system in bacteria
4. Team finds a better way to watch bacteria swim
5. UT Knoxville and ORNL researchers reveal key to how bacteria clear mercury pollution
6. Taking sharper aim at stomach ulcer bacteria
7. Light, photosynthesis help bacteria invade fresh produce
8. Comprehensive understanding of bacteria could lead to new insights into many organisms
9. Yale engineers track bacterias kayak paddle-like motion for first time
10. Caltech scientists get detailed glimpse of chemoreceptor architecture in bacterial cells
11. U of C alumnus finds high numbers of heat-loving bacteria in cold Arctic Ocean
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... , Mar. 26, 2015 Research and Markets ... the "Global Gesture Recognition Market in Automotive Sector ... analysts forecast the Global Gesture Recognition market in Automotive ... the period 2013-2018. Gesture recognition is the ... different gestures of an individual. Gesture recognition technology can ...
(Date:3/24/2015)... GARDENS, Fla. , March 24, 2015 /PRNewswire/ ... identity management solutions, today announced that its U.are.U ... clothing accessory retailer Goorin Bros . to ... Crossmatch biometrics-based solution secures access to the POS ... the increased risk of data breaches. ...
(Date:3/20/2015)... DUBLIN , Mar. 20, 2015 Research ... announced the addition of the "India Sensors ... their offering. The sensor market is ... through 2020 Consumer electronics, automotive, industrial ... for sensors in the country. In addition, adoption ...
Breaking Biology News(10 mins):Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3
... Ill. (September 25, 2008) A light-transmitting compound that ... and in sensors to detect biological and chemical weapons ... its structure was too difficult to examine. Luckily, ... and Northwestern University were able to determine the structure ...
... global scientific community will gather in Maputo, Mozambique, 21-24 ... International Council for Science (ICSU)the first time an ICSU ... than 250 leading scientists from around the world will ... address how science can contribute to solving some of ...
... green may be heart healthy if the green ... at Penn State who conducted the first study ... "We investigated mechanisms of action to explain the ... K. Gebauer, recent Penn State Ph.D. recipient, currently ...
Cached Biology News:Argonne scientists peer into heart of compound that may detect chemical, biological weapons 2Global science community to gather in Mozambique 2Researchers study how pistachios may improve heart health 2
(Date:5/4/2015)... 4, 2015 /PRNewswire/ - Fluorinov Pharma (Fluorinov), a ... appointment of Dr. Roger J Garceau, to its ... companies in matters including corporate development and clinical ... adds significant regulatory expertise as Fluorinov transitions to ... 30 years of pharmaceutical development experience to Fluorinov ...
(Date:5/4/2015)... PRINCETON, N.J. , May 4, 2015  Soligenix, ... biopharmaceutical company developing products that address unmet medical needs ... today that it will be presenting preclinical data from ... and Biological Defense Science and Technology Conference on May ... Convention Complex at 701 Convention Plaza, St. ...
(Date:5/4/2015)... VIEJO, Calif. , May 4, 2015   ... eliminate preventable hospitalizations, has teamed with the Scripps ... of Sentrian technology on 1,000 patients with chronic obstructive ... 13 million Americans and is the nation,s third leading ... members of CareMore Health System , a wholly ...
(Date:5/1/2015)... , May 1, 2015 Pfenex ... engaged in the development of biosimilar therapeutics including ... today that its first quarter 2015 financial results ... before the open of market. At 8:30 am Eastern ... to discuss the financial results and provide a ...
Breaking Biology Technology:Roger J Garceau joins Fluorinov board, adds clinical expertise to bromodomain program and oncology pipeline 2Roger J Garceau joins Fluorinov board, adds clinical expertise to bromodomain program and oncology pipeline 3Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 2Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 3Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 4Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 5Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 6Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 7Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 8Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 9Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 10Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 11Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 12CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 2CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 3CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 4CareMore, Scripps Translational Science Institute, and Sentrian Launch Landmark Study of Remote Patient Monitoring for COPD Population 5Pfenex To Report First Quarter 2015 Results and Provide Business Update on Thursday, May 14, 2015 2
... of the U.S. Department of Energy (DOE),s Lawrence ... of California (UC) Berkeley,s Larry and Diane Bock ... Foundation Prize in Chemistry for 2012. Alivisatos is ... pioneer in the synthesis of semiconductor quantum dots ...
... LCAV ), a leading provider of laser vision ... that management will present at the Noble Financial Eighth Annual ... 3:00 p.m. Eastern time.  A live and archived webcast of ... of LCA-Vision,s website at www.lasikplus.com . The conference is ...
... Oxford BioTherapeutics (OBT) today announces that it ... and non-executive director.  Dr Begley, who was the Vice President ... will take on a key role in helping shape and ... pipeline of oncology antibody-based drugs into clinical development. ...
Cached Biology Technology:Berkeley Lab Director Paul Alivisatos wins Wolf Prize in Chemistry 2Berkeley Lab Director Paul Alivisatos wins Wolf Prize in Chemistry 3Oxford BioTherapeutics Appoints C. Glenn Begley as a Senior Clinical Advisor and Non-executive Director 2Oxford BioTherapeutics Appoints C. Glenn Begley as a Senior Clinical Advisor and Non-executive Director 3
Perm/Wash Buffer 250 Tests...
Mouse monoclonal to OCIL ( Abpromise for all tested applications)....
... Large T antigen initiates replication ... replication in the presence of ... product can be used in ... Replication Kit cat. no. 8050. ...
NuParaffin Kit Application: Flow Cytometry Reactivity: Human...
Biology Products: