Navigation Links
Bacteria in mouth may diagnose pancreatic cancer
Date:5/18/2014

Patients with pancreatic cancer have a different and distinct profile of specific bacteria in their saliva compared to healthy controls and even patients with other cancers or pancreatic diseases, according to research presented today at the annual meeting of the American Society for Microbiology. These findings could form the basis for a test to diagnose the disease in its early stages.

"Our studies suggest that ratios of particular types of bacteria found in saliva may be indicative of pancreatic cancer," says Pedro Torres of San Diego State University who presented the research.

In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagnosed in the early stages of pancreatic cancer have a 5-year survival rate of 21.5%. Unfortunately symptoms do not appear until after the cancer has become untreatable in the vast majority of cases, says Torres.

In the study, Torres and his colleagues compared the diversity of saliva bacteria across 131 patients, 63 female and 68 male, being treated at the University of California, San Diego (UCSD) Moores Cancer Center. Of these patients, 14 had been diagnosed with pancreatic cancer, 13 with pancreatic disease, 22 with other forms of cancer and 10 disease free. Results showed that patients diagnosed with pancreatic cancer had higher levels of two particular oral bacteria, Leptotrichia and Campylobacter, when compared to any other healthy or diseased state including non-cancerous pancreatic disease. Those with pancreatic cancer also had lower levels of Streptococcus, Treponema and Veillonella.

"Our results suggest the presence of a consistently distinct microbial profile for pancreatic cancer," says Torres. "We may be able to detect pancreatic cancer at its early stages by taking individuals' saliva and looking at the ratios of these bacteria."


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Related biology news :

1. Bacteria in urine could contribute to overactive bladder
2. Chemists design molecules for controlling bacterial behavior
3. No bioengineered gut bacteria, no glory
4. Hijacking bacterias natural defences to trap and reveal pathogens
5. Galectins direct immunity against bacteria that employ camouflage
6. IU biologists receive $6.2 million to advance research on bacterial evolution
7. Immune cells outsmart bacterial infection by dying, Penn Vet study shows
8. Undersea warfare: Viruses hijack deep-sea bacteria at hydrothermal vents
9. Lonely bacteria increase risk of antibiotic resistance
10. Plants send out signals attracting harmful bacteria, MU study finds
11. How a plant beckons the bacteria that will do it harm
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... NEW YORK , March 21, 2017 /PRNewswire/ ... Customer Marketing Cloud used by retailers such as ... in its platform — Product Recommendations and Replenishment. Using ... to give more personalized product and replenishment recommendations ... purchases, but also on predictions of customer intent ...
(Date:3/20/2017)... March 20, 2017 At this year,s CeBIT Chancellor ... biometrics manufacturer DERMALOG. The Chancellor came to the DERMALOG stand together with ... this year,s CeBIT partner country. At the largest German biometrics company the ... fingerprint, face and iris recognition as well as DERMALOG´s multi-biometrics system.   ... ...
(Date:3/16/2017)... , March 16, 2017 CeBIT 2017 - Against identity fraud with ... Reading ... Used combined in one project, multi-biometric solutions provide a crucial ... Used combined in ... ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... Mar 23, 2017 Research and Markets ... Markets" report to their offering. ... The Global Market for ... in 2016 at a CAGR of 8.9%, ... non-energetic bioproducts into seven major product segments: bio-derived chemicals, biofuels, ...
(Date:3/23/2017)... ... March 23, 2017 , ... Ellen ... the Connecticut Technology Council (CTC) as a 2017 Women of Innovation® finalist. Matloff ... of Innovation Awards Dinner. , The dinner recognizes women accomplished in science, technology, ...
(Date:3/23/2017)... -- In today,s pre-market research, Stock-Callers.com takes ... industry: Sangamo Therapeutics Inc. (NASDAQ: SGMO), Eyegate Pharmaceuticals Inc. ... Regulus Therapeutics Inc. (NASDAQ: RGLS ). On ... rating on Pharmaceuticals/Biotechnology to "Overweight" from "Market Weight." Learn more about ... ...
(Date:3/22/2017)... Calif. , March 22, 2017  UBM ... proud to announce their extended partnership and the ... be headlined by the 21 st Annual ... Boston, taking place May 3-4, 2017. ... Medical Technology Association (ADVAMED) President and CEO, ...
Breaking Biology Technology: