Navigation Links
Bacteria in mouth may diagnose pancreatic cancer
Date:5/18/2014

Patients with pancreatic cancer have a different and distinct profile of specific bacteria in their saliva compared to healthy controls and even patients with other cancers or pancreatic diseases, according to research presented today at the annual meeting of the American Society for Microbiology. These findings could form the basis for a test to diagnose the disease in its early stages.

"Our studies suggest that ratios of particular types of bacteria found in saliva may be indicative of pancreatic cancer," says Pedro Torres of San Diego State University who presented the research.

In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagnosed in the early stages of pancreatic cancer have a 5-year survival rate of 21.5%. Unfortunately symptoms do not appear until after the cancer has become untreatable in the vast majority of cases, says Torres.

In the study, Torres and his colleagues compared the diversity of saliva bacteria across 131 patients, 63 female and 68 male, being treated at the University of California, San Diego (UCSD) Moores Cancer Center. Of these patients, 14 had been diagnosed with pancreatic cancer, 13 with pancreatic disease, 22 with other forms of cancer and 10 disease free. Results showed that patients diagnosed with pancreatic cancer had higher levels of two particular oral bacteria, Leptotrichia and Campylobacter, when compared to any other healthy or diseased state including non-cancerous pancreatic disease. Those with pancreatic cancer also had lower levels of Streptococcus, Treponema and Veillonella.

"Our results suggest the presence of a consistently distinct microbial profile for pancreatic cancer," says Torres. "We may be able to detect pancreatic cancer at its early stages by taking individuals' saliva and looking at the ratios of these bacteria."


'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Related biology news :

1. Bacteria in urine could contribute to overactive bladder
2. Chemists design molecules for controlling bacterial behavior
3. No bioengineered gut bacteria, no glory
4. Hijacking bacterias natural defences to trap and reveal pathogens
5. Galectins direct immunity against bacteria that employ camouflage
6. IU biologists receive $6.2 million to advance research on bacterial evolution
7. Immune cells outsmart bacterial infection by dying, Penn Vet study shows
8. Undersea warfare: Viruses hijack deep-sea bacteria at hydrothermal vents
9. Lonely bacteria increase risk of antibiotic resistance
10. Plants send out signals attracting harmful bacteria, MU study finds
11. How a plant beckons the bacteria that will do it harm
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... , Mar 24, 2017 Research and Markets ... System Market Analysis & Trends - Industry Forecast to 2025" ... ... grow at a CAGR of around 15.1% over the next decade ... industry report analyzes the market estimates and forecasts for all the ...
(Date:3/22/2017)... 21, 2017   Neurotechnology , a provider ... today announced the release of the SentiVeillance ... improved facial recognition using up to 10 surveillance, ... computer. The new version uses deep neural-network-based facial ... it utilizes a Graphing Processing Unit (GPU) for ...
(Date:3/20/2017)... At this year,s CeBIT Chancellor Dr. Angela Merkel visited the ... the DERMALOG stand together with the Japanese Prime Minster Shinzo Abe. ... largest German biometrics company the two government leaders could see the three ... as DERMALOG´s multi-biometrics system.   Continue Reading ... ...
Breaking Biology News(10 mins):
(Date:7/26/2017)... , ... July 25, 2017 , ... ... media and software solutions that enable short-run digital printing, is proud to announce ... and its free GHS Wizard online software available at avery.com/GHS . The ...
(Date:7/26/2017)... ... 2017 , ... Provia Laboratories announces the launch ... and development of human cells and tissues for therapeutic use. Provia’s state of ... Administration’s (FDA) Current Good Manufacturing Practices (cGMP) guidelines and provides contract services related ...
(Date:7/26/2017)... ... July 26, 2017 , ... ... for the improvement of crop productivity and economics for the food, feed and ... scope of the agreement includes the research and development of microbiome-based seed treatments ...
(Date:7/25/2017)... ... July 25, 2017 , ... ... and improve efficiency of livestock farming while reducing the use of antibiotics and ... intellectual property from Cornell University. , These new proprietary technologies expand the ...
Breaking Biology Technology: