Navigation Links
Bacteria from sponges make new pharmaceuticals
Date:9/3/2007

Thousands of interesting new compounds have been discovered inside the bodies of marine sponges according to scientists speaking today (Tuesday 4 September 2007) at the Society for General Microbiologys 161st Meeting at the University of Edinburgh, UK, which runs from 3-6 September 2007.

Over half of the bodyweight of living sea sponges including the sort that we use in our baths is made up of the many different bacteria that live inside them, in the same way that we all have bacteria living in our guts which help us to digest our food.

Marine sponges are the most prolific and important source of new active compounds discovered in the last twenty or thirty years in our seas. We thought it likely that many of the interesting new compounds we were discovering inside sea sponges were actually being made by the bacteria inside their bodies, not the sponges themselves, says Dr Detmer Sipkema of University College Berkeley, in California, USA.

Unfortunately the scientists discovered that it is very difficult to grow these bacteria in the laboratory, as the environment inside a sponge is significantly different from conditions in the surrounding seawater. Currently, only between one in a hundred and one in a thousand types of bacteria can be cultured artificially.

We are trying to culture the other 99% by simulating the microenvironment in the sponge where the bacteria live, says Dr Sipkema. The next step will be to identify which bacteria are responsible for the production of the most medically interesting compounds and try to culture these on a larger scale. Most attempts to properly test these important bioactive compounds in hospital patients have failed because doctors simply cannot get enough of the products to prove that the clinical trials are effective or safe.

So far, by trying a lot of different cultivation methods, the scientists have been successful in culturing about 10% of the different sorts of bacteria that live in the sponges.

As well as their attempt to produce useful pharmaceutical compounds on a commercial scale, the researchers believe that successfully culturing these little known bacteria will give new insights into evolution.

Marine sponges were the first multicellular organisms to evolve on earth that are still alive. This implies that the relationship between the sponge and its bacterial inhabitants may also be very old, says Dr Detmer Sipkema. Therefore sponges are interesting to study the evolution of symbiosis, teaching us about the way different organisms have developed their mutual relationships.


'/>"/>
Contact: Lucy Goodchild
l.goodchild@sgm.ac.uk
44-011-898-81843
Society for General Microbiology
Source:Eurekalert

Related biology news :

1. Anti-bacterial additive widespread in U.S. waterways
2. Bacteria collection sheds light on urinary tract infections
3. A bacterial genome reveals new targets to combat infectious disease
4. Solution to Pollution: New Bacteria Eats Toxic Waste
5. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
6. The Bacterias guide to survival
7. Scientists discover that host cell lipids facilitate bacterial movement
8. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
9. Family trees of ancient bacteria reveal evolutionary moves
10. Drug-resistant bacteria on poultry products differ by brand
11. Programmable cells: Engineer turns bacteria into living computers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... 28, 2017 The report "Video ... Monitors, Servers, Storage Devices), Software (Video Analytics, VMS), and ... Global Forecast to 2022", published by MarketsandMarkets, the market ... is projected to reach USD 75.64 Billion by 2022, ... The base year considered for the study is 2016 ...
(Date:3/23/2017)... , Mar. 23, 2017 Research and Markets ... Market Analysis & Trends - Industry Forecast to 2025" report ... ... at a CAGR of around 8.8% over the next decade to ... report analyzes the market estimates and forecasts for all the given ...
(Date:3/20/2017)... March 20, 2017 PMD Healthcare announces the ... and Wellness Management System (WMS), a remote, real-time lung ... 2010, PMD Healthcare is a Medical Device, Digital Health, ... dedicated to creating innovative solutions that empower people to ... intent focus, PMD developed the first ever personal spirometer, ...
Breaking Biology News(10 mins):
(Date:5/26/2017)... ... ... LabRoots , the leading provider of scientific trending news and interactive ... a new textbook scholarship, the second scholarship in the LabRoots program. , This ... pursuing a degree in one of the life sciences. The scholarship will provide one ...
(Date:5/24/2017)... ... May 24, 2017 , ... Patient Monitoring ... with Wi-Fi connectivity to reduce the amount of wiring in a healthcare facility ... compact mobile devices including infusion pumps, heart and hypertension monitoring, glucose monitoring, and ...
(Date:5/23/2017)... ... May 23, 2017 , ... Genedata, a leading provider of ... occasion with a strong presence at Bio-IT World Conference & Expo 2017 in ... invitation to all attendees to view posters on the entire range of ...
(Date:5/23/2017)... ... 23, 2017 , ... Kathy Goin is joining myClin ... brings years of expertise in establishing and leading clinical operations at Sponsors including ... occupational therapist, through a variety of leadership roles in Clinical Operations, to her ...
Breaking Biology Technology: