Navigation Links
Backstabbing bacteria: A new treatment for infection?
Date:9/5/2010

Selfish bacterial cells that act in their own interests and do not cooperate with their infection-causing colleagues can actually reduce the severity of infection.

The selfish behaviour of these uncooperative bacteria could be exploited to treat antibiotic-resistant infections, according to research being presented at the Society for General Microbiology's autumn meeting today.

Bacteria work together by using a well-studied communication system called Quorum Sensing (QS). During infection, bacteria talk to each other using QS to coordinate the release of toxins.

Researchers at the University of Nottingham have discovered that in Staphylococcus aureus infections, bacteria defective in QS can benefit from 'opting out' of toxin production. By doing so, they can invest more energy in reproducing whilst taking advantage of the nutrient-rich infection that is maintained by their neighbours.

By looking after themselves in this way, QS-deficient bacteria are quickly able to outnumber other bacteria that are busy producing toxins. As a result the overall severity of infection is reduced as fewer toxins are produced. "This opens up the interesting possibility of using these uncooperative bacteria to treat infection," said Mr Eric Pollitt who is presenting the study.

The group tested the theory by introducing S. aureus into waxworms that subsequently developed infections. "We found that the QS-deficient bacteria could not only outgrow normal bacteria in the same population, but that they could also invade other cooperating populations to reduce the severity of infection," explained Mr Pollitt. "This means that we could potentially isolate QS-deficient bacteria and use them to treat clinical S. aureus infections."

New approaches for the treatment of S. aureus infections are desperately needed as many strains of the bacterium, such as Meticillin-resistant Staphylococcus aureus (MRSA),
'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Breast cancer treatment resistance linked to signaling pathway
2. The dietary supplement genistein can undermine breast cancer treatment
3. Coming soon: Self-guided, computer-based depression treatment
4. Nanodiamond drug device could transform cancer treatment
5. Disinfectants can make bacteria resistant to treatment
6. Scientists from Granada find a potential treatment to prevent diabetes and obesity
7. FSU researchers discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
8. Researchers at National Jewish Health evaluating a treatment
9. National Jewish Health researchers evaluating treatment to help emphysema sufferers breathe easier
10. First comprehensive genomic study of common cold reveals new treatment targets
11. Iowa State researcher develops new treatment method for canine eye diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... to undertake jaunts into the countryside each year could come ... century, according to new research. , Climate change could postpone ... as summer temperatures linger later into the year, Princeton University ... . For instance, the paper birch a popular foliage ... could change color one to three weeks later by the ...
(Date:9/18/2014)... 18, 2014 -- Arizona turned its newborn screening program into ... short months, earning it the first-ever Newborn Screening Quality Award ... Dimes presented Will Humble, M.P.H., Arizona,s Department of Health Services ... Mr. Humble established a policy of full transparency for the ... blood samples to the lab for analysis, and set a ...
(Date:9/18/2014)... The tropical rabbitfish which have devastated algal forests in ... the entire Mediterranean basin if their distribution continues to ... The study, by an international team of researchers led ... Fiona Tomas of the Mediterranean Institute for Advanced Studies ... Ecology ., Members of the team surveyed more than ...
Breaking Biology News(10 mins):Fall foliage season may be later, but longer on warmer Earth 2Fall foliage season may be later, but longer on warmer Earth 3Fall foliage season may be later, but longer on warmer Earth 4March of Dimes honors Arizona with first-ever newborn screening award 2March of Dimes honors Arizona with first-ever newborn screening award 3Tropical fish a threat to Mediterranean Sea ecosystems 2
... has landed a University of Central Florida scientist more ... could have profound benefits in the search for cures ... Annette Khaled is conducting research into what triggers the ... surrounding cells. If its secrets could be unlocked and ...
... Contaminated seaweeds in Sydney Harbour could be threatening the small ... revealing that the harbour,s seaweeds have the world,s highest levels ... of the offspring of small crustaceans that feed on a ... exposed to copper at levels found in some parts of ...
... early diagnosis of Alzheimers, Parkinsons and other diseases has ... Jersey Technology Council competition. Based at NJITs business ... , a start-up company, was named most likely to ... entrepreneurs and investors. NeuroTrax develops ...
Cached Biology News:'Death protein' research secures funding for UCF scientists 2Sydney harbors deadly diet for sea creatures 2NJIT start-up company NeuroTrax named best in show 2
(Date:9/19/2014)... -- , The first grants awarded to ... (ESPE) Meeting  Investment supports innovative projects for ... field of growth  , EMD Serono, a ... , today announced the first recipients of the Grant ... announced during a Satellite Symposium organized by EMD Serono ...
(Date:9/18/2014)... About POCT POCT, ... clinical laboratory. It helps in making fast clinical ... medication. POCT is gaining popularity due to the ... as diabetes, heart disease, and obesity. It is ... to minimize errors during the diagnosis of patients. ...
(Date:9/18/2014)... September 18, 2014 ... http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has announced the addition ... Global Strategic Business Report" report ... ,This report analyzes the worldwide markets ... by the following Product Segments: Polymeric ...
(Date:9/18/2014)... -- Research and Markets has announced ... Report 2014" report to their offering. ... is a professional and in-depth study on the ... The report provides a basic overview of ... chain structure. The N-acetylcysteine market analysis is provided ...
Breaking Biology Technology:EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3POCT Market in China 2014-2018 2Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3Global N-acetylcysteine Industry Report 2014 2
... EU Citizens (6%) Have Liver Diseases, 5th Most Common Cause of ... ... Abuse Takes 13,000,Number With Fatty Liver Disease Stable or Growing; Viral Hepatitis Declines, ... world gathered today in this historic Italian,city to attend the opening sessions of ...
... one for analyzing tumors , Doctors treating individuals with ... oxygen in a tumor very useful, because low levels of oxygen ... new method to do this and to image the surrounding organs ... to image tumors in mice by Murali Krishna and colleagues, at ...
... the biggest-selling,biologics developed during the boom years in biotech ... have lost patent,protection in the U.S. in 2007 or ... This opens up a huge potential market for biosimilars, ... report by Kalorama,Information, Biogenerics: the World Market for Biosimilars., ...
Cached Biology Technology:Liver Diseases: A Huge European Health Burden, But Some Trends are Positive 2Liver Diseases: A Huge European Health Burden, But Some Trends are Positive 3JCI table of contents: April 22, 2008 2JCI table of contents: April 22, 2008 3JCI table of contents: April 22, 2008 4JCI table of contents: April 22, 2008 5JCI table of contents: April 22, 2008 6JCI table of contents: April 22, 2008 7JCI table of contents: April 22, 2008 8JCI table of contents: April 22, 2008 9JCI table of contents: April 22, 2008 10JCI table of contents: April 22, 2008 11JCI table of contents: April 22, 2008 12Huge Potential in Biosimilars if Generic Providers Overcome Regulatory Hurdles 2
...
... Kit Components , 25 g Blocking Reagent , ... 10 ml T7 Elution Buffer , 0.2 ml BL21 ... 0.2 ml BLT5615 glycerol stock , 1010 pfu ... Control Lysate , 50 l S-protein HRP Conjugate , ...
Mouse monoclonal [7A6] to NFAT2 ( Abpromise for all tested applications). entrezGeneID: 4772 SwissProtID: O95644...
... are designed for ultra-sensitive detection of ... PVDF membranes. Since all necessary reagents ... antibodies), the WesternBreeze Kits save you ... and getting your final results. Solutions ...
Biology Products: