Navigation Links
Baby's obesity risk: What's the mother's influence?
Date:3/15/2010

This release is available in Spanish.

Aspiring moms may be advised to achieve a healthy weight before they become pregnant, and to gain only the recommended amount of weight during their pregnancy. Now ongoing studies by Agricultural Research Service (ARS)-funded investigator Kartik Shankar and colleagues could provide new insights into those recommendations.

Shankar is taking a new, closer look at how influences that occur in the womband perhaps during the first few months of lifemight affect development of a child's ability to regulate his or her weight later in life.

In fact, the child's body-weight-regulating mechanisms might be permanently altered by maternal signals associated with the mother's own overweight, according to Shankar. Such maternal programming of the unborn child could increase the risk that the child would become an overweight or obese adult and would have a higher risk of obesity-related afflictions.

A preliminary study that Shankar and his group published in the American Journal of Physiology--Regulatory, Integrative and Comparative Physiology several years ago has led to follow-up investigations now under way in his laboratory. He is based at the ARS Arkansas Children's Nutrition Center in Little Rock, Ark., where he is also an assistant professor of pediatrics at the University of Arkansas for Medical Sciences.

Shankar looked at weight gains among rat pups whose dads were lean and whose mothers, called "dams," were either lean or overweight (from overfeeding) before conception and throughout pregnancy.

All offspring were of normal weight at birth and at weaning. However, when the weaned offspring were given free access to an unlimited amount of high-fat rations, the offspring of overweight dams showed remarkable sensitivity to the high-fat rations. They gained significantly more weight, and more of that weight as fat mass, than did the offspring of lean dams.

The study strongly suggests that exposure to the mother's obesity while in the womb results in programming of the offspring's metabolism and body-weight-control mechanisms. The dams' obesity alone was sufficient to significantly increase the pups' susceptibility to obesity.


'/>"/>

Contact: Marcia Wood
Marcia.Wood@ars.usda.gov
301-504-1662
United States Department of Agriculture-Research, Education, and Economics
Source:Eurekalert

Related biology news :

1. Male dinosaurs may have been prehistoric babysitters, study shows
2. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
3. Obesity and lack of exercise could enhance the risk of pancreatic cancer
4. Obesity and the central nervous system -- the state of the art
5. Obesity-related hormone is higher in children with Down syndrome
6. Australian researchers develop treatment to treat obesity
7. Study suggests link between obesity, poor bone health
8. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
9. Overeating and obesity triggered by lack of BDNF
10. Human hormone blocker found to help prevent obesity and diabetes: study
11. Moms obesity during conception phase may set the stage for offsprings obesity risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/16/2016)... June 16, 2016 The ... expected to reach USD 1.83 billion by 2024, ... Research, Inc. Technological proliferation and increasing demand in ... expected to drive the market growth. ... The development of advanced multimodal techniques for ...
(Date:6/9/2016)... TURKU, Finland , June 9, 2016 ... French National Police deploy Teleste,s video security solution to ensure ... France during the major tournament ... and data communications systems and services, announced today that its ... Police Prefecture to back up public safety across ...
(Date:6/2/2016)... LONDON , June 2, 2016 ... has awarded the 44 million US Dollar project, ... Security Embossed Vehicle Plates including Personalization, Enrolment, and IT Infrastructure ... world leader in the production and implementation of Identity Management ... in January, however Decatur was selected ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... ... STACS DNA Inc., the sample tracking software company, today announced that Dr. ... STACS DNA as a Field Application Specialist. , “I am thrilled that Dr. ... STACS DNA. “In further expanding our capacity as a scientific integrator, Hays brings a ...
(Date:6/23/2016)... June 23, 2016 Apellis Pharmaceuticals, Inc. ... clinical trials of its complement C3 inhibitor, APL-2. ... multiple ascending dose studies designed to assess the ... subcutaneous injection in healthy adult volunteers. ... as a single dose (ranging from 45 to ...
(Date:6/23/2016)... Andrew D Zelenetz ... Published recently in Oncology ... touchONCOLOGY, Andrew D Zelenetz , discusses the ... is placing an increasing burden on healthcare systems ... With the patents on many biologics expiring, interest ...
(Date:6/23/2016)... ... June 23, 2016 , ... ClinCapture, the only free ... and will showcase its product’s latest features from June 26 to June 30, ... poster on Disrupting Clinical Trials in The Cloud during the conference. DIA ...
Breaking Biology Technology: