Navigation Links
Baby's obesity risk: What's the mother's influence?
Date:3/15/2010

This release is available in Spanish.

Aspiring moms may be advised to achieve a healthy weight before they become pregnant, and to gain only the recommended amount of weight during their pregnancy. Now ongoing studies by Agricultural Research Service (ARS)-funded investigator Kartik Shankar and colleagues could provide new insights into those recommendations.

Shankar is taking a new, closer look at how influences that occur in the womband perhaps during the first few months of lifemight affect development of a child's ability to regulate his or her weight later in life.

In fact, the child's body-weight-regulating mechanisms might be permanently altered by maternal signals associated with the mother's own overweight, according to Shankar. Such maternal programming of the unborn child could increase the risk that the child would become an overweight or obese adult and would have a higher risk of obesity-related afflictions.

A preliminary study that Shankar and his group published in the American Journal of Physiology--Regulatory, Integrative and Comparative Physiology several years ago has led to follow-up investigations now under way in his laboratory. He is based at the ARS Arkansas Children's Nutrition Center in Little Rock, Ark., where he is also an assistant professor of pediatrics at the University of Arkansas for Medical Sciences.

Shankar looked at weight gains among rat pups whose dads were lean and whose mothers, called "dams," were either lean or overweight (from overfeeding) before conception and throughout pregnancy.

All offspring were of normal weight at birth and at weaning. However, when the weaned offspring were given free access to an unlimited amount of high-fat rations, the offspring of overweight dams showed remarkable sensitivity to the high-fat rations. They gained significantly more weight, and more of that weight as fat mass, than did the offspring of lean dams.

The study strongly suggests that exposure to the mother's obesity while in the womb results in programming of the offspring's metabolism and body-weight-control mechanisms. The dams' obesity alone was sufficient to significantly increase the pups' susceptibility to obesity.


'/>"/>

Contact: Marcia Wood
Marcia.Wood@ars.usda.gov
301-504-1662
United States Department of Agriculture-Research, Education, and Economics
Source:Eurekalert

Related biology news :

1. Male dinosaurs may have been prehistoric babysitters, study shows
2. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
3. Obesity and lack of exercise could enhance the risk of pancreatic cancer
4. Obesity and the central nervous system -- the state of the art
5. Obesity-related hormone is higher in children with Down syndrome
6. Australian researchers develop treatment to treat obesity
7. Study suggests link between obesity, poor bone health
8. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
9. Overeating and obesity triggered by lack of BDNF
10. Human hormone blocker found to help prevent obesity and diabetes: study
11. Moms obesity during conception phase may set the stage for offsprings obesity risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2016)... NEW YORK , May 16, 2016   ... authentication solutions, today announced the opening of an IoT ... to strengthen and expand the development of embedded ... provides an unprecedented level of convenience and security with ... to authenticate one,s identity aside from DNA. EyeLock,s platform ...
(Date:5/9/2016)... Elevay is currently known as ... for high net worth professionals seeking travel for work ... world, there is still no substitute for a face-to-face ... your deal with a firm handshake. This is why ... of citizenship via investment programs like those offered by ...
(Date:4/28/2016)... SAN FRANCISCO and BANGALORE, India ... part of EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... service provider, today announced a global partnership that ... convenient way to use mobile banking and payment services. ... Mobility is a key innovation area for financial services, but ...
Breaking Biology News(10 mins):
(Date:5/19/2016)... There is no saying when ... relentless pressures in pricing and lack in consumer confidence. ... though - numerous opportunities are up for grabs but ... presents four names in this sector: Portola Pharmaceuticals Inc. ... VTAE ), Anthera Pharmaceuticals Inc. (NASDAQ: ...
(Date:5/19/2016)... DIEGO , May 19, 2016 ... (OTC PINK: RGBP) and (OTC PINK: RGBPP) announced today ... creating the first cord blood based cancer immunotherapeutic ... provisional patent application, Regen described a generation of ... was potentiated by gene silencing.  The product in ...
(Date:5/18/2016)... ... 2016 , ... Tech Coast Angels (TCA) today announced that the ... the annual ACA Summit last week in Philadelphia. , The award recognizes ... angel groups. It is the highest honor available for an early-stage company to receive ...
(Date:5/18/2016)... , May 18, 2016 The Biotech ... does not mean that there are no opportunities ahead. Today, ... Inc. (NASDAQ: THLD ), Seattle Genetics Inc. (NASDAQ: ... ), and Ophthotech Corp. (NASDAQ: OPHT ). Sign ... at: http://www.activewallst.com/ Threshold Pharmaceuticals ...
Breaking Biology Technology: