Navigation Links
BWH researchers develop a vaccine prototype stronger than traditional vaccines
Date:11/28/2011

BWH's Channing Laboratory. "So these may be the first true carbohydrate-specific T-cells found."

The understanding that it was not only proteins, but also carbohydrates that were being recognized by cells led researchers to design a vaccine that yielded many carbohydrate particles when processed by the immune systemin turn creating a vaccine that generated a stronger immune response. Researchers believe that the more effective vaccine prototype they designed may one day assist in protecting high-risk populations susceptible of disease.

"For example, pneumococcal conjugate vaccines are good in children, but are not effective in protecting the elderly," explained Kasper. So we are hopeful that by designing vaccines like this, you'll make better vaccines that will be effective in all the at-risk populations."

Fikri Avci, PhD, lead study author and instructor in the Department of Medicine at BWH and Harvard Medical School adds that the findings on how the body's immune cells interact with carbohydrates will also lead to more effective vaccines in the future.

"Carbohydrates are among the most abundant and structurally diverse molecules in nature," said Avci. "They are extremely important in many biological functions. A better understanding of carbohydrate interaction is crucial. We are hoping that our findings will provide a framework for production of new-generation therapeutics and preventive medicines not only against bacterial infections, but also for cancer and viral diseases."


'/>"/>

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
Source:Eurekalert

Page: 1 2

Related biology news :

1. NC State researchers get to root of parasite genome
2. Researchers find animal with ability to survive climate change
3. Researchers find an essential gene for forming ears of corn
4. Researchers note differences between people and animals on calorie restriction
5. Researchers study acoustic communication in deep-sea fish
6. Researchers discover that growing up too fast may mean dying young in honey bees
7. Researchers study how pistachios may improve heart health
8. UI researchers find potentially toxic substance present in Chicago air
9. Researchers develop new self-training gene prediction program for fungi
10. Case Western Reserve University researchers track Chernobyl fallout
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/10/2015)... 2015 Fingerprint Cards (FPC) has received ... from the distributor World Peace Industrial Group (WPI), part of ... Asia . Deliveries are planned to take place ... smartphone manufacturers in China . The order ... guidance of + 1 000 MSEK for 2015.   ...
(Date:5/5/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... market, reminds investors and media that  Mr. David Tunnell ... SECURE CONNEXIONS AMERICA 2015, held in Washington DC ... conference is organized into a series of nine session tracks. ... Fraud: Where is the Trust in Cyberspace? and will ...
(Date:4/21/2015)... , April 21, 2015 ... evolving government policies are boosting access control systems market ... According to a recently published report by TechSci ... 2020 ", the access control systems market in ... USD1.2 billion by 2020.The access control systems market in ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 235 Million 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3
... at the University of Virginia have discovered a new ... storage and transportation of energy much more efficient ... Bellave S. Shivaram and Adam B. Phillips, the U.Va. ... finding at 8 p.m., Monday, Nov. 12, at the ...
... study led by researchers at the University of Southern California ... distinct changes in the density of nucleosomes within the cells. ... the journal Cancer Cell, will enable researchers to explore new ... to novel treatments for human cancers, says study lead author ...
... On September 10, 2007, ConsumerLab.com issued ... contain label amounts of folic acid. One of these ... part of U. S. Pharmacopeias (USP) Dietary Supplement Verification ... to the report, USP studied the verified product to ...
Cached Biology News:Scientists discover record-breaking hydrogen storage materials for use in fuel cells 2Market testing of dietary supplements and drugs underscores value of USP's public health programs 2
(Date:6/2/2015)... AKRON, Ohio , June 2, 2015 ... today pledged its commitment to antibiotic stewardship at the ... and human and animal health organizations and stakeholders at ... next five years to slow the emergence of antibiotic-resistant ... existing antibiotics, and prevent the spread of resistant infections. ...
(Date:6/1/2015)... (PRWEB) June 02, 2015 Chosen ... health care, Jack Uldrich has been selected as ... New York today. He will deliver his keynote: ... Uldrich has delivered presentations to the American Medical ... Audiology and Neurology, Alcetel-Lucent/Verizon Forum on Wireless Healthcare, ...
(Date:6/1/2015)... GenomeDx Biosciences today announced that ... classified various subtypes of bladder cancer based ... including one type associated with resistance to ... has potential as a tool to predict ... with muscle-invasive bladder cancers (MIBC). The study ...
(Date:6/1/2015)... BAY HEAD, N.J. , June 1, 2015 /PRNewswire/ ... to launch a national innovative science curriculum for high ... announcement at the 16 th annual LIFE Event ... held at Mountain Ridge Country Club in ... some of the LPGA,s biggest stars raised more than ...
Breaking Biology Technology:GOJO Among Leaders At The White House Forum On Antibiotic Stewardship 2GOJO Among Leaders At The White House Forum On Antibiotic Stewardship 3GOJO Among Leaders At The White House Forum On Antibiotic Stewardship 4Futurist Jack Uldrich to Address the Future of Pharmaceuticals 2GenomeDx's Decipher Platform Validates Genomic Signature that may Predict Resistance to Chemotherapy in Bladder Cancer Patients in Study Presented at ASCO 2015 Annual Meeting 2GenomeDx's Decipher Platform Validates Genomic Signature that may Predict Resistance to Chemotherapy in Bladder Cancer Patients in Study Presented at ASCO 2015 Annual Meeting 3GenomeDx's Decipher Platform Validates Genomic Signature that may Predict Resistance to Chemotherapy in Bladder Cancer Patients in Study Presented at ASCO 2015 Annual Meeting 4Val Skinner Foundation Announces Partnership With Discovery Education 2
... Inc. (Nasdaq: GHDX ) today announced that ... will present at the JMP,Securities Healthcare Focus Conference ... 10:00 a.m. ET., To access the live ... Investor Relations section of Genomic Health,s,website at ...
... Sept. 30 Cell Therapeutics, Inc.,(CTI) (Nasdaq and MTA: ... Milan,Italy on October 3, 2008. The investor day will ... and regulatory milestones,for the Company. Additionally, Alessandro Gianni, M.D., ... the University of Milan,who has authored over 300 publications ...
... (Nasdaq: SGMO ) announced today that Edward Lanphier,Sangamo,s ... progress of,Sangamo,s ZFP Therapeutic development programs and an overview ... Monday, October 6, 2008,at the 2008 JMP Securities Healthcare ... 7, 2008 at the William Blair Small Cap Conference.,Both ...
Cached Biology Technology:Cell Therapeutics Provides Details on Investor & Media Day to be Held in Milan, Italy on Friday, October 3, 2008 2Sangamo BioSciences to Present at Two Upcoming Investor Conferences 2
The ELISA Kit for Hepatitis B Surface Antigen (HBsAg) is an in vitro enzyme immunoassay for the detection of HBsAg in human serum or plasma....
2,4-Dinitrophenyl hapten is conjugated to Keyhole Limpet (KLH) protein through lysine....
Alexa Fluor 350/488/594 Filter Set (Semrock Brightline) *mounted* *Zeiss Axio AF...
IC50: 3 ng/ml · Limit of detection: 0.5 ng/ml...
Biology Products: