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BUSM researchers identify novel approach to study COPD and treatment efficacy
Date:4/11/2013

D patients before and after they started steroid therapy. They found that the expression of some genes that changed due to COPD reversed their expression after treatment and started to look more like the levels seen in current or former smokers without COPD.

"Part of the COPD 'signature' reverses with therapy, suggesting that examining airway cells might be a minimally invasive tool for monitoring the disease and evaluating the response to therapy more quickly in order to determine the best course of treatment for each individual patient," said Marc Lenburg, PhD, associate professor in computational biomedicine and bioinformatics at BUSM and the study's other senior co-author.

"Studying COPD using the large airway opens up some really exciting new avenues of research that could also improve care for patients with COPD," said Spira. "While we are still at an early stage, I envision being able to examine airway cells from my patients with COPD to determine what is causing the disease and, from that information, recommend a more specific and effective treatment."


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Contact: Jenny Eriksen
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

Page: 1 2 3

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