Navigation Links
BUSM researchers find potential key to halt progression, reverse damage from emphysema
Date:8/31/2012

the structure of their actin cytoskeleton and in cell adhesion, especially to collagen," said James Hogg, MD, from the University of British Columbia and one of the study's senior authors. "GHK also restored the ability of cells to reorganize themselves to repair wounds and construct the contractile filaments essential for alveolar tissue repair."

GHK is a natural peptide found in human plasma, but the amount present decreases with age. While more testing needs to be done on its effects in COPD, these early results are very promising. Therapeutic studies with GHK in animal models of COPD are now underway with the ultimate goal of moving this compound into clinical trials. As more gene activity signatures are discovered, this method of matching drug to disease may provide a rapid method for discovering potential uses for existing drugs and compounds.

"Beyond the identification of a potential new COPD drug, the research team developed a cost-effective approach to study COPD at the molecular level across the entire lung, and then screen potential drug candidates," said James Kiley, PhD, director of the NHLBI's Division of Lung Diseases, who supported this work. "This work demonstrates the potential of using genomics data to drive clinical research."


'/>"/>

Contact: Jenny Eriksen
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Researchers launch new Rust-Tracker to monitor deadly wheat fungus in 27 nations
2. University of Tennessee Space Institute researchers make clinical trials a virtual reality
3. New equipment is breath of fresh air for childrens lung researchers
4. Mount Sinai researchers solve mystery surrounding the death of two sisters nearly 50 years ago
5. Stanford researchers discover the anternet
6. By detecting smallest virus, researchers open possibilities for early disease detection
7. Behind closed doors: Researchers show how probiotics boost plant immunity
8. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
9. University of Minnesota engineering researchers discover new non-invasive method for diagnosing epilepsy
10. Researchers describe new molecular interactions behind the inhibition of TGF beta-signaling
11. U of M researchers: Newly discovered genetic markers could signal colon cancer development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/17/2013)... Research Foundation and Horizon Pharma further establish their commitment ... 2013 AGA-Horizon Pharma Fellow Abstract Prizes and the 2013 ... year, this competition continues to grow in popularity among ... basic and clinical research," said Nicholas F. LaRusso, MD, ... extremely proud of all that these fellows and students ...
(Date:6/17/2013)... of mining shale gas, is widespread across Pennsylvania, covering ... research in the Annals of the New York ... biodiversity including pollution from toxic chemicals, the building of ... "Shale gas has engendered a great deal of controversy, ... effects on biological diversity and resources have scarcely been ...
(Date:6/16/2013)... (June 16, 2013)Male mice who were fed a high-fat ... offspring who also had higher levels of body fat, ... was observed primarily in male offspring, despite their consumption ... annual meeting of The Endocrine Society in San Francisco, ... may affect metabolism and behavior of offspring dependent on ...
Breaking Biology News(10 mins):Horizon Pharma Abstract Prizes recognize promising fellows and students 2Obese male mice father offspring with higher levels of body fat 2
... making a sentence sound like a question? But actually, being ... may be a sign of superior empathy? A new study ... the same brain regions to produce and understand intonation in speech. ... mirror neurons. This study shows for the first time that prosody ...
... Nanyang Technological University (NTU) and Rice University ... agreed to jointly establish the Institute of Sustainable ... the multidisciplinary bi-national institute will create new science ... systems and other radical new information technologies that ...
... and respond to electric fields is the aim of ... to Min Zhao, professor of dermatology and ophthalmology at ... Living cells are already known to respond to ... light, temperature and chemical signals. Understanding this mechanism would ...
Cached Biology News:Music in speech equals empathy in heart? 2NTU, Rice establish infodynamics institute 2NTU, Rice establish infodynamics institute 3
(Date:6/18/2013)... The human skin is the largest organ, ... human body part. Similar to the liver, or heart, the ... repair and grow. Recent reports from the mankatofreepress.com explained how ... as important as other life supporting organs. The article suggests ... cell reproduction, increase the appearance of skin, and fight off ...
(Date:6/18/2013)... Nasseo, Inc. today announces that it ... of hundreds of applicants by the Arizona Commerce ... Challenge . The Arizona Innovation Challenge (AIC) awards the ... challenge, granting a financial award to what it deems ... state of the art dental and orthopedic implant surface ...
(Date:6/18/2013)... June 18, 2013 The ... of the HELM biomolecular representation standard software toolkit ... licence. HELM (Hierarchical Editing Language for ... of biomolecules (e.g. proteins, nucleotides, antibody drug conjugates) ... sequence-based informatics methodologies impractical or unusable. HELM solves ...
(Date:6/18/2013)... LONDON , June 18, 2013 /PRNewswire/ ... leading international investment research firm, announces the ... (BIO.PA), a French biopharmaceutical company developing and ... supportive care indications.      (Logo: ... a comprehensive report examining the investment merits ...
Breaking Biology Technology:Natural Acne Remedies Through Diet, Probiotic Action Shares New Insight on What Foods May Help Lead to Clear Skin 2Nasseo Named 2013 Innovation Challenge Winner by Arizona Commerce Authority 2The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools 2Edison Expands French Healthcare Sector Coverage With Initiation of Coverage on BioAlliance Pharma 2Edison Expands French Healthcare Sector Coverage With Initiation of Coverage on BioAlliance Pharma 3
... , ... for spaces leased to biotech, pharma and medical devices tenants are faring better in some ... ... the recession, the credit crunch, pharmaceuticals industry mergers and an overall slump in the commercial ...
... MUMBAI, July 24 , ... Annual Executive,MindXchange on Biotechnology Applications in the Food & Beverage ... food processing industry has seen some spectacular product,developments such as ... A lot more has to be achieved through cutting,edge R&D ...
... Open Monoclonal Technology, Inc. (OMT), in collaboration with ... The Medical College of Wisconsin, and INSERM, today announced ... detailed in "Knockout Rats Produced via Embryo Microinjection of ... issue of Science . The creation of ...
Cached Biology Technology:Life Sciences Real Estate Outperforming Other Sectors 2Life Sciences Real Estate Outperforming Other Sectors 3Growing Awareness and Increased Investments Lead to Growth of Biotechnology Applications in the Food & Beverage and Dietary Supplements Sector, Reveals Frost & Sullivan 2Growing Awareness and Increased Investments Lead to Growth of Biotechnology Applications in the Food & Beverage and Dietary Supplements Sector, Reveals Frost & Sullivan 3Growing Awareness and Increased Investments Lead to Growth of Biotechnology Applications in the Food & Beverage and Dietary Supplements Sector, Reveals Frost & Sullivan 4OMT announces a breakthrough in the development of a novel human antibody platform 2
... The kit for stabilizing 50g of purified ... StabMRT Plus Kit delivers all of the advantages ... but in addition the RNA can be used ... , This product has been optimised for the ...
Puromycin resistance gene (pac), provided in a pORF plasmid. pORF is an expression plasmid selectable with Ampicillin....
...
Hygromycin resistance gene (hph), provided in a pORF plasmid. pORF is an expression plasmid selectable with Ampicillin....
Biology Products: